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Repetitive Testing of Anti-dsDNA Antibodies May Predict Flares in SLE
In abstract #0327 presented during the poster session on Saturday, Dr. Ai Li Yeo and colleagues investigated the usefulness of serial anti-dsDNA testing in predicting flares among SLE patients who have persistently positive anti-dsDNA titers.
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"Serum complement levels are the Rosetta Stone for understanding lupus activity in pregnancy." Dr. Stone @RheumNow #ACR22 https://t.co/4FbThAZyvq
Dr. Rachel Tate uptoTate ( View Tweet)
Raynaud's may not be first presenting symptom in SSc with RNA Pol3 antibodies. May be a mimic of early inflammatory arthritis. Implications for steroid use.
@RheumNow #ACR22 #Pearls https://t.co/FO8dtOTn9V
Julian Segan JulianSegan ( View Tweet)
How is BASDAI reflecting dis activity in pregnant women w/ AS?
Back pain and fatigue from 2nd sem onwards & BASDAI in 3rd sem = poor sens & spe.
Morning stiffness = highest classification value. https://t.co/pafKqpmZFq
Abstr #0374 #ACR22 @Rheumnow https://t.co/IJY0hm01GW
Aurelie Najm AurelieRheumo ( View Tweet)
“Not always bilateral symmetrical arthropathy”
Early RA also px
💥Asymmetric Oligoarthritis
OR
💥Migratory oligoarthritis
🔥not to miss in mig. oligoarthritis
👉ANCA - GPA /MPA
🦵LL>UL
✅GC response
#ACR22 @RheumNow #rheumpearls
Patricia Harkins DrTrishHarkins ( View Tweet)
Narain et al. SSA/SSB and RO52 abs in IIM with ILD. No difference with SSA/SSB+ . RO52+ lung function more likely to decline over time. FVC, p = 0.0117; FEV1, p = 0.0045; DLCO p = 0.0027 @rheumnow #ACR22 Abstr#0164 https://t.co/ixHOwPJAT2 https://t.co/sIkolMoVqk
Richard Conway RichardPAConway ( View Tweet)
Eshagh @TerrierBen et al. AAV in SSC patients. It does happen! 30 cases. More common in lcSSc, Scl70+, fibrosing ILD. Mostly MPA with +MPO and renal disease. @rheumnow #ACR22 Abstr#0435 https://t.co/Qa4LpbQxZX https://t.co/22L9zt8DOG
Richard Conway RichardPAConway ( View Tweet)
Fascinating. Folle et al. Using neural networks to distinguish seropositive RA, seronegative RA, and PsA based on MRI. Especially mind-blowing that can separate sero+ and sero- RA @rheumnow #ACR22 Abstr#242 https://t.co/GvVpzcGxxo https://t.co/jowHXIOF2v
Richard Conway RichardPAConway ( View Tweet)
#RheumPearl: "A creatinine 1.0 mg/dL is likely abnormal in a pregnant patient; pregnancy normally increase eGFR, normal Cr should be 0.4-0.7 mg/dL" - Dr. J Stone @rheumnow #ACR22 https://t.co/PcQGnRdMYZ
TheDaoIndex KDAO2011 ( View Tweet)
Review meds in someone with a flare of cutaneous lupus. These common meds can be culprits.
@RheumNow #ACR22 #Pearls https://t.co/IUer9OqA5W
Julian Segan JulianSegan ( View Tweet)
Abs 0381 at #ACR22 Suggests that ASDAS superior to BASDAI in clinical practice based on gender outcomes. Female gender assoc'd w/ less favorable outcomes across the SpA spectrum, except for CRP. What do you use in clinical practice? @RheumNow https://t.co/HzjPq9KbAH https://t.co/9MU93MkxFN
Dr. Rachel Tate uptoTate ( View Tweet)
Song et al. : cit-specific CD4+ T cells activated & expanded in CCP+ at-risk RA, CCP+ RA converters and early RA pts.
Circulating Ag specific CD4+ T cells < RA converters vs. at-risk pts. Could this be due to migration in the joints?
https://t.co/Vp0Rbwv6RB
#0498 #ACR22 @Rheumnow https://t.co/NoN1ocjC70
Aurelie Najm AurelieRheumo ( View Tweet)
45% of unselected idiopathic uveitis found to have underlying SpA. Don't stop thinking at the diagnosis of AAU.
@RheumNow #ACR22 #Pearls https://t.co/w9zXz6gzUX
Julian Segan JulianSegan ( View Tweet)
#RheumPearl: Pattern of uveitis differs in different SpA Dr. J Kolfenbach #ACR22 @rheumnow https://t.co/Au5zfX2Q5Z
TheDaoIndex KDAO2011 ( View Tweet)
In early hip OA, look for underlying FAI (amongst other secondary causes. Surgical intervention however is very controversial.
@RheumNow #ACR22 #Pearls https://t.co/Gg4EtbnGiT
Julian Segan JulianSegan ( View Tweet)
Aggarwal @docrota et al. TYK2/JAK1i brepoctinib in dermatomyositis. Supportive clinical and pharmacological evidence, plus efficacy of other JAK agents, likely to lead to a clinical trial. @rheumnow #ACR22 Abstr#0157 https://t.co/Tz6dHfyUmq https://t.co/0R0tcuCe6D
Richard Conway RichardPAConway ( View Tweet)
"Behind the difficult to treat RA is a person!" Dr. Iris Navarro-Millán, MD reminds us to treat the patient, not just the disease! #ACR22 @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
#RheumPearl FVC:DLCO ratio can be helpful to disting. b/t ILD and PAH. FVC:DLCO = 1 is seen in ILD. when the ratio > 1.6, typically assc with pulm vasc dz (e.g, PE, PAH) #ACR22 @rheumnow https://t.co/a7JJCLtv2N
TheDaoIndex KDAO2011 ( View Tweet)
🌟Subclinical GCA in PMR🌟
👉25pts PMR
👉US of TA and AX arteries
💥5(20%) US evidence of GCA (TA in 5/5, AX in 1/5)
💥1yr f/up -all 5 developed clinical GCA
❓Time to rethink our assessment of PMR pts ❓
Abst#0478
#ACR22 @RheumNow @colmkirby22
#ACRbest https://t.co/PynxF7wIck
Patricia Harkins DrTrishHarkins ( View Tweet)
Dr. Kolfenbach reminds us that scleritis isn't always red or painful! #ACR22 @RheumNow https://t.co/B5N0wE7LOL
Dr. Rachel Tate uptoTate ( View Tweet)