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Culerrier @AKronbichler @TerrierBen et al. AAV induced by anti-thyroid drugs. 45 cases. vs AAV - younger (45 vs 68) More skin (54 vs 25%) Less renal (38 vs 73%) Less severe (BVAS 9 vs 13) Less relapse (HR 0.07). Can rechallenge! @rheumnow #ACR22 Abstr#0436 https://t.co/0i7zj615N6 https://t.co/t7fWCOuUsJ
Richard Conway RichardPAConway ( View Tweet)
OPAL data is a gem! Large Australian data studying JAKi use in #rheumatoidarthritis N=5900 Switching JAKi~JAKi-common. As in TNFi 1st line Rx had longer retention & better efficacy than 2nd & subsequent. Median 1st advanced Rx - same in all JAKs 34 MOA @RheumNow #ACR22 abst0274 https://t.co/FQU4AKXwe9
Janet Pope Janetbirdope ( View Tweet)
Dey @DrMiniDey @ElenaNikiUK @docrota @LatikaGupta_ et al. COVID vaccination in IIM+multimorbidity. Adverse events more common, but still infrequent. Both multimorbidity and active IIM increased risk of AEs. @rheumnow #ACR22 Abstr#0177 https://t.co/HA5NaRrPYL https://t.co/TKtagwa0gG
Richard Conway RichardPAConway ( View Tweet)
Coming soon on #ACR22:
Stream session 12S119 on @ACRheum and @ACRheumDC advocacy
What is new on the Hill?
What are ACR priorities
How quickly can you send an email supporting rheumatologists (quicker than you think!)
@RheumNow
@AngusWorthing @BlairSolowM @LennMcD @LouisaZiglar https://t.co/sXSBGbCZyM
Eric Dein ericdeinmd ( View Tweet)
Froehlich et al. MRI superior to US in GCA. For all GCA sensitivity 73% vs 45%. For supra-aortic GCA sensitivity 73% vs 59%. Both 100% specificity. @rheumnow #ACR22 Abstr#0493 https://t.co/vf2r0h5zUd https://t.co/mlSCcpy2uK
Richard Conway RichardPAConway ( View Tweet)
Very complex conversation on why opioids are used...
Opioid use in patients with PsA and AS led to higher healthcare utilization and higher costs.
Opioid users - more co-morbidities, smokers, worse disease activity
Opioid users spent more on drug costs
Abs#0402 @RheumNow #ACR22 https://t.co/dbUPg5LGLy
Robert B Chao, MD doctorRBC ( View Tweet)
Rathmann et al. Incidence/Prevalence AAV in Sweden over time. Incidence stable. Prevalence increasing and higher in men. Incidence increases with age and commonest 70-84 years @rheumnow #ACR22 Abstr#0451 https://t.co/yCMOC7dAvq https://t.co/y0tqkaV8zX
Richard Conway RichardPAConway ( View Tweet)
#ACR22 Abstr#2081 What is the nature of breakthrough #COVID infection in #lupus patients in Omicron era? A cohort study in New York showed those receiving booster vac were less likely to develop infection vs receiving 2 vaccine doses. Only 2 hospitalised, no deaths @RheumNow https://t.co/6UaTMN5Dev
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Rooney et al. Seasonality of GCA in UK and Ireland - DCVAS/TABUL/local hospital combined dataset. 2 peaks - spring/early summer every year, and a second peak most years in autumn or winter. @rheumnow #ACR22 Abstr#0495 https://t.co/Trz8ou9xGh https://t.co/jcS3Z30nz8
Richard Conway RichardPAConway ( View Tweet)
Do you see #JAKis causing weight gain? 429 Pts BUT during #COVID19 - 68% gained wt in RA 1.5 Kg mean; and more in SpA 71% w 2.6 Kg. Was it Rx or COVID related? #ACR22 abst0291 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Ruiz et al. bDMARD/tsDMARD use in RA after breast cancer. Low use, 15.5% on bDMARD, 1.5% on tsDMARD. Stable use over last 10 years @rheumnow #ACR22 Abstr#0080 https://t.co/0L6uuVtQQw https://t.co/xBH1bUdeSD
Richard Conway RichardPAConway ( View Tweet)
#disparities study using admin data
- 580 pts with incidence childhood #SLE with LN
- LN codes before SLE codes - more likely publicly insured, rural area, Hispanic ethnicity, kidney transplant
- differential access!!
@RADoctor @rheumnow #ACR22 abst#0068 https://t.co/uryCZq94dX
Bella Mehta bella_mehta ( View Tweet)
Early Izokibep (IL17Ai) data demonstrated clinically meaningful, dose-dependent improvement across PROs, particularly sleep, pain, function ,+ SF36 and PsAID subdomains in PsA pts. Pts w/ baseline enthesitis had greater benefit. Abs 0199 #ACR22 @RheumNow https://t.co/sXVdwGPVnd https://t.co/Cxyfp6OXOY
Dr. Rachel Tate uptoTate ( View Tweet)
Did you get the updated #COVIDbooster before you arrived at #ACR22? Answers are anonymous @rheumnow
TheDaoIndex KDAO2011 ( View Tweet)
Use of AI to detect sacroilitis in axSpA and nr-axSpA.
Pre-trained AI neural network can detect sacroilitis, especially new data, similar to human radiology experts.
Abs#0383 @RheumNow #ACR22 https://t.co/5hdrKxT3HP
Robert B Chao, MD doctorRBC ( View Tweet)
‼️Frailty in Vasculitis‼️
👉VascStrong using VPPRN
✏️ FRAIL scale
👉 n=328
🌟21.6% frail
🌟42.1% pre frail
💥 frailty assoc ⬆️ pain, fatigue and ⬇️ mood and fn
💥⬆️ wt and females higher frailty
Abst0444
#ACR22 #GeriRheum @RheumNow @SattuiSEMD
Patricia Harkins DrTrishHarkins ( View Tweet)
Elderly onset #rheumatoid #arthritis does worse than younger people. Data from Japan - Benefit is less and side effects more. Less remission and worse HAQ scores. ?due to RA differences or changes due to age or both or neither? #ACR22 abst0244 @RheumNow @ACRheum https://t.co/FqvLA765Cu
Janet Pope Janetbirdope ( View Tweet)
Remuzgo-Martinez et al. Serum endothelin-1 in CTD-ILD. Significantly higher levels than healthy controls. No difference between CTD-ILD and IPF. @rheumnow #ACR22 Abstr#0123 https://t.co/Jf3AumSnjt https://t.co/Xki8LEEcnV
Richard Conway RichardPAConway ( View Tweet)
de Boysson et al. Beta-blockers may prevent aortic dilation in LVV GCA (0% vs 23%). 65 patients, retrospective , and patients were on beta-blockers for other reasons, but thought-provoking @rheumnow #ACR22 Abstr#0477 https://t.co/AVmIwCk3LV https://t.co/Plv5tcN5mR
Richard Conway RichardPAConway ( View Tweet)
Auroux et al report differential micro-RNA signatures in hand OA compared to controls (15 upregulated, 4 downregulated). No difference erosive vs non-erosive hand OA. May elucidate pathophys but also ?treatment target @rheumnow #ACR22 Abstr#0023 https://t.co/Kzv8WDmHRU https://t.co/4nCuTjvR6d
Richard Conway RichardPAConway ( View Tweet)