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Women with Rheumatic Disease (11.4.2022)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.com.  New regulatory decisions about JAK inhibitors and why do women with rheumatic diseases have unfair outcomes?

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Undiagnosed RA During the Pandemic

d EurekAlert!

The number of new diagnoses of rheumatoid arthritis fell by 20% in the first year of the COVID-19 pandemic, new research suggests.

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Target,T2T,bullseye

SLE T2T - Lupus Low Disease Activity State Predicts Outcomes

d Jack Cush, MD

Treat-to-target management of SLE has been shown to protect against organ damage and to improve quality of life. Now a prospective study shows that T2T with a goal of lupus low disease activity state and remission has been shown to improve mortality risk.

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2022 CDC Clinical Practice Guideline on Opioid Prescribing

d CDC

The CDC has updated its Guideline for Prescribing Opioids for Chronic Pain and includes recommendations for managing acute (duration of <1 month), subacute (duration of 1–3 months), and chronic (duration of >3 months) pain.

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DLE discoid lupus

ACR Promotes CME on Lupus Clinical Trials Racial Disparities

d ACR

The American College of Rheumatology (ACR) has released Continuing Medical Education (CME) for dermatologists and nephrologists to help them learn more about clinical trials for lupus patients in their respective treatment areas and the importance of getting more of their African American/Black p

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Can You Withdraw Ixekizumab in Stable Axial Spondyloarthritis?

d Jack Cush, MD

Remission often invites consideration of drug withdrawal in patients with axial spondyloarthritis (axSpA).

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“At the ACR I am looking forward to meeting colleagues in person, having some great food in Philadelphia and to learning alot as a RheumNow reporter!” Dr. Janet Pope is back for #ACR22 as a RheumNow reporter, sharing real-time coverage on many topics. Follow her @Janetbirdope https://t.co/ROD7oan4KZ
Dr. John Cush RheumNow ( View Tweet)
SLE T2T - Lupus Low Disease Activity State Predicts Outcomes A prospective study shows that T2T with a goal of LLDAS and remission has been shown to improve mortality risk. https://t.co/WRaqjdVi9G https://t.co/3guKt0Qby9

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Dr. John Cush RheumNow ( View Tweet)
2022 CDC Clinical Practice Guideline on Opioid Prescribing The CDC has updated its Guideline for Prescribing Opioids for Chronic Pain and includes recommendations for managing acute, subacute, and chronic pain. https://t.co/aFE4fUpIWn https://t.co/kG8QlVy2bG

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Dr. John Cush RheumNow ( View Tweet)
Population study shows among vaccinated gout pts, COVID breakthrough infection occurred in @ 4.68/1K Pt-mos vs 3.76/1K Pt-mos in non-Gout persons. Gout w/ Covid had More Hosp (aHR=1.30) & death (aHR=1.36), moreso in Women w/ gout (aHR 1.55 & 2.46) https://t.co/ViwiPzqTbZ https://t.co/BrXd6pbgRI

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Dr. John Cush RheumNow ( View Tweet)
Multinatinal cross-sectional survey of 2270 PsA pts shows despite comparable Dz duration, presentation, biologic use (54%), Women had worse QOL, more disability and work activity impairment (but less comorbidities) https://t.co/1KbDuxaMFf https://t.co/SsbSHQNsPV

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Dr. John Cush RheumNow ( View Tweet)
BIOBADASER registry study of 969 axSpA pts (315 females, 654 males; 2000-2019) who initiated a TNFi shows nonresponse (BASDAI50) was more likely in women (p=0.018), older age at the start of TNFi therapy. https://t.co/Zp7PWhEMav https://t.co/1XY0dC0QCW

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Dr. John Cush RheumNow ( View Tweet)
Single center study from UAB shows 72 gout pts treated & D/C from ED were Rx w/ steroids (64%), opioids (63%), NSAIDs (43%), colchicine (32%). But only 26/72 (36%) had subsequent outpatient clinic visit for gout. https://t.co/I8jjqIqJXd https://t.co/05YSibd6iz

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Dr. John Cush RheumNow ( View Tweet)
JAK inhibitor labeling in Canada updated to include risks of MACE, fatal VTE and cancer for tofacitinib (Xeljanz) (also applied to Cibinqo, Inrebic, Jakavi, Olumiant, Rinvoq Xeljanz) https://t.co/FEbHE4wN3I https://t.co/EN80i9cY5h

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Dr. John Cush RheumNow ( View Tweet)
Dr. Chao will be covering PsA and AS for the RheumNow team at #ACR22. “I’m looking forward to the exciting hybrid format of both in person and virtual meeting this year!” Follow @doctorRBC for real-time #ACR22 coverage. https://t.co/3sbBhVPPZ2
Dr. John Cush RheumNow ( View Tweet)
Introducing Dr. Akhil Sood, who will be covering #ACR22 on behalf of RheumNow. He is excited to learn more about the cutting-edge research in the field of Rheumatology & Immunology. Follow him @AkhilSoodMD for real-time coverage! https://t.co/hXw2CMrwKF
Dr. John Cush RheumNow ( View Tweet)
🆕Recommendation provided by Pharmacovigilance Risk Assessment Committee (#PRAC) about Janus kinase inhibitors #JAKi ⏩EMA recommends measures to minimise risk of serious side effects with #JAKi for chronic inflammatory disorders. https://t.co/YqaX7UxtUA https://t.co/dCJbqanAxF

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Renaud Felten DocFelten ( View Tweet)
Think about checking Ig levels prior to Rituximab administration. Low IgM was most common after RTX in RA. The following are risk factors for hypogammaglobulinemia: 🧪 Older age 🧪 Use of steroids 🧪 Repeated doses of RTX 🧪 Low Ig at baseline https://t.co/oOjqnmFdYt
Catherine Sims, MD DrCassySims ( View Tweet)
RheumNow #ACR22 reporter, Dr. Bella Mehta, will be covering SLE, gout and auto inflammatory topics this year. “I am looking forward to meeting collegues at ACR after 2 years!” -Dr. Mehta Follow @bella_mehta for real-time coverage during #ACR22. https://t.co/QQM2NrObPR
Dr. John Cush RheumNow ( View Tweet)
Follow our newest #ACR22 reporter, Dr. Julian Segan ( @JulianSegan)! “I am looking forward to is meeting all my rheumatology Twitter heroes!” Follow @RheumNow and our reporters for real-time #ACR22 coverage. https://t.co/7axxfOV6W8
Dr. John Cush RheumNow ( View Tweet)

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