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psoriatic.PIP_.JPG

Biologic Persistence in Psoriatic Arthritis and Psoriasis

d Jack Cush, MD

Two recent studies examined the durability and persistence of biologic agents in patients with psoriasis (PSO) and psoriatic arthritis (PsA) and while some differences were noted overall persistence was low 3 years later.

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Inflammation,reflex,neural

Inflammatory Arthritis Spread by ATP and Neural Crosstalk

d Jack Cush, MD

A novel study from the Journal of Experimental Medicine suggests that a reflex neural signaling at sites of inflammation may lead to spread to other inflammatory sites via and ATP-mediated neural crosstalk.

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PSS.hands_.Raynauds.jpg (keep)

Relevance of Raynaud’s in Systemic Sclerosis

d Jack Cush, MD

Raynaud’s phenomenon (RP) is integral to the diagnosis and management of systemic sclerosis (SSc) patients; a recent analysis suggests that RP should be characterized based on color change and the presence of other symptoms to know whether RP portends more serious manifestations.

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SpA,RNL,2022

RNL 2022: Spondyloarthritis Spectrum

d Jack Cush, MD

This RheumNow Live 2022 session features highlights from lectures on Spondyloarthritis.



- Microbiome in Spondyloathritis - Jose Scher, MD



- Axial Psoriatic Arthritis - Philip Mease, MD



- Juvenile Spondyloathritis - Pamela Weiss, MD


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Ontario population study shows that musculoskeletal disorders account for 12.3% of all adult emergency dept. visits and 28.5% outpatient physician visits https://t.co/Sq9n7RkIYK https://t.co/lKtQqR5Ja3

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Dr. John Cush RheumNow ( View Tweet)
Watch: The Almighty ANA Dr. Lipsky discussed how our thinking and use of ANA and serologic testing has evolved and is crucial to outcomes and trials in his lecture, The Almighty ANA, presented during the at #RNL2022 in March. #lupus https://t.co/Xxxj18badY https://t.co/5pwV4xSGDx

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Dr. John Cush RheumNow ( View Tweet)
Local cryotherapy in adjuvant-induced arthritis in rats given bid resulted in lower arthritis scores, structural damages, less vascular inflammation/endothelial activation (less mRNA CXCL-1, IL-6, IL-1β, leukocyte infiltration, lower IL-17A and OPG https://t.co/b4cAa9E4PJ https://t.co/vhwWoY8Ujw

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Dr. John Cush RheumNow ( View Tweet)
RCT (WBC) whole body cryotherapy (-130C x 3 min; 6 WBC in 14 d) in 56 RA pts. Pain at 2 wks was signif better in WBC than controls (-2 vs -0.88 ; p=0.003) & remained lower x 12 weeks (w less pain meds); Dz activity & Function improved but not signif @wk 12 https://t.co/K7a7CQ7rGj https://t.co/a8QgiDeJS6

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Dr. John Cush RheumNow ( View Tweet)
Many have quoted and shown this image of Ankylosing Spondylitis in a young military recruit at age 25, 35, 45, 50 & 51yrs. This may be the MOST used slide in rheum! It comes from the work of Toronto's Dr. Hugh Little, who sadly passed away at age 58 yrs. https://t.co/PGrwBEtrQd https://t.co/948G3SUHvV

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Dr. John Cush RheumNow ( View Tweet)
Watch: Pregnancy Paradox: How Stopping Drugs Leads to Greater Harm Uma Mahadevan, MD talks about the pregnancy paradox and how stopping medications in pregnancy to protect the fetus can actually lead to greater harm. https://t.co/HYO5BdjwzZ https://t.co/IGeZ3O8Dno

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Dr. John Cush RheumNow ( View Tweet)
Large Granular Lymphocyte Leukemia rarely assoc w/ #RA. LGL accounts for 2-5% of lymphoprolif. disorders; often assoc w/ Autoimmune Dz (mostly RA). RA w/ LGL presents with leukopenia, anemia, splenomegaly, onset after mean 6 yrs of RA https://t.co/AIz2edHDXp https://t.co/DoHKm3KS7d

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Dr. John Cush RheumNow ( View Tweet)
Machine Learning helps predict RA relapse: data from KURAMA, 210 RA pts (150 achieved remission; 60 relapsed). Using clinical, lab and US findings, ML identified US findings in wrist and MTP predictors of relapse https://t.co/9rhctim4Mh https://t.co/iK3JudOMsC

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Dr. John Cush RheumNow ( View Tweet)
Interested in what we covered in the month of April? You can find all our PsA content at the link below. What was your biggest takeaway from our PsA All the Way campaign? https://t.co/s5duGwoWeo https://t.co/lTqBKBHg0g

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Dr. John Cush RheumNow ( View Tweet)
Multimorbidity Burden in Rheumatoid Arthritis Crowson and colleagues at the Mayo Clinic have shown that rheumatoid arthritis (RA) patients have a higher prevalence of multimorbidity with as many as 44 different morbidities of interest in RA. https://t.co/vgC1dCA7kZ https://t.co/fLOaa1PDGU

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Dr. John Cush RheumNow ( View Tweet)
Rising Incidence of Systemic Lupus Erythematosus Data from Olmstead county, MN over the past four decades shows that the incidence and prevalence of systemic lupus erythematosus (SLE) is increasing. https://t.co/LCDmVS5UVb https://t.co/f3z6BlURkj

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Dr. John Cush RheumNow ( View Tweet)
The global axial spondyloarthritis (therapeutics) market was estimated to be at $1.87 Billion in 2021, and is expected to grow to $7.9 billion by 2032 https://t.co/P9TUUBoneM https://t.co/qfBdkvCdru

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Dr. John Cush RheumNow ( View Tweet)
Tuesday Night Rheumatology: Spondyloarthritis Spectrum https://t.co/4QW8dNGJQq

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Dr. John Cush RheumNow ( View Tweet)

@RheumNowNews has already taken a shot at this but let us try : HOW MANY RITUXIMAB pts do you have on EVUSHELD pre exposure prophylaxis for #COVID19 @CCalabreseDO @PaulSaxMD @philipcrobinson @JYazdanyMD @DrPujaMehta1 @jeffsparks @zach_wallace_md @alhkim

Leonard Calabrese LCalabreseDO ( View Tweet)

And now the paper that no one can find even if they are looking for it. On the relationship between disease activity and glucocorticoid disease. https://t.co/aT8I0jwQOJ @rheum_covid @ARD_BMJ https://t.co/7ntGLPdypJ

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The COVID-19 Global Rheumatology Alliance rheum_covid ( View Tweet)
Dr. Robert Rosenberg, a founding physician of Arthritis and Rheumatism Associates, is retiring after 44 years effective 5/31/22. ARA extends our deepest gratitude and sincerest thanks for his decades of service and exceptional patient care. We wish him well in his retirement. https://t.co/mYQODUk5VY
Arth and Rheum Assoc ARARheum ( View Tweet)

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