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Drug Naming Games (2.7.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news, regulatory and journal reports from the past week on RheumNow.com.

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Granzyme - a major driver of inflammatory & autoimmune diseases

EurekAlert!

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that patrols our body, ever vigilant for signs of infection or injury.

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ACR Commends Legislation Addressing Harmful Medicare Payment Cuts to Physicians

ACR

The American College of Rheumatology (ACR) applauded the bipartisan introduction of the Medicare Patient Access and Practice Stabilization Act of 2025, legislation to fully offset the harmful 2.8% cut in the Medicare Physician Fee Schedule (MPFS).

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Recent Excess Mortality in Young Adults

Jack Cush, MD

JAMA has published a University of Minnesota cross-sectional study showing early adult (ages 25-44) mortality in the U.S. has risen substantially between 2011 to 2019 and 2020 to 2023. The largest portion of 2023 excess mortality was driven by drug poisoning, but many other external and natural causes exceeded what prior trends would have projected.

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Participation is Up! (1.31.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. We also have two call-in cases on "Ask Cush Anything".

Be sure to join in the fun at RNL 2025 next weekend - Gong Show Karaoke; what will you sing?

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Such an important topic from @UnaMakris . The intersection of aging with our rheumatic disease processes is a crucial area. @RheumNow @RNL2025 https://t.co/n0Kx559g9e

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Richard Conway RichardPAConway ( View Tweet)
J Curtis #RNL2025 @RheumNow AI Will Not Replace You - AI cannot replace human interaction, examination, procedures, interpreting guidelines for an individual, providing empathy, and facilitate good patient education Will become a tool... but not a replacement to a good clinician https://t.co/qPcNOjWepi

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Eric Dein ericdeinmd ( View Tweet)
AI is here to stay! It should be our ally in optimizing patient care and efficiency at work. Here are the 10 commandments of AI from an amazing lecture from @RADoctor at #RNL2025 #AI #Rheumatology @RheumNow https://t.co/6BajZxGkwe

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Adela Castro AdelaCastro222 ( View Tweet)
QD Clinic - New Palmoplantar Psoriasis and PsA New Onset Palmoplantar PsO and PsA - what are the options? Features Dr. Jack Cush. QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025 Register at https://t.co/2dcFVgu8z6… https://t.co/3ubBL6HVGF https://t.co/Zdd6Dih5eZ

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Dr. John Cush RheumNow ( View Tweet)
BSR Guideline on Management of Sjögren disease The British Society for Rheumatology has published its guideline for the management of adult and juvenile onset Sjogren's disease. https://t.co/UJOvb937lk https://t.co/P77h91nPuN

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Dr. John Cush RheumNow ( View Tweet)
QD Clinic - dsDNA without Lupus Insufficient Sxs to Dx SLE, but persistent dsDNA positivity - what to do? Features Dr. Jack Cush. QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025 Register at https://t.co/2dcFVgu8z6… https://t.co/ov8THqrPyC https://t.co/jmtqxcWzJ0

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Dr. John Cush RheumNow ( View Tweet)
QD Clinic - New Palmoplantar Psoriasis and PsA New Onset Palmoplantar PsO and PsA - what are the options? Features Dr. Jack Cush. QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025 Register at https://t.co/2dcFVgu8z6… https://t.co/HZZuDvga58 https://t.co/wWKhnIECwB

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Dr. John Cush RheumNow ( View Tweet)
Seats are still available for virtual attendees! Join us THIS WEEKEND for RheumNow Live! https://t.co/kSd7tKywmM https://t.co/oyyY5EK04m

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Dr. John Cush RheumNow ( View Tweet)
Participation is Up! (1.31.2025) Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow. We also have two call-in cases on "Ask Cush Anything". https://t.co/kxMkDW5X8c https://t.co/AjIuNzk7co

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Dr. John Cush RheumNow ( View Tweet)
How did Rheumatology go from being the happiest specialist to now being 5th from the bottom at 65%? Top heavy happiness seems to be influenced by income? what do you think? Allergy 94% Pathology 88% Dermatology 87% .... Rheum 67% Internal med 66%... https://t.co/YTKMElL868 https://t.co/RnsIVYWBFo

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Dr. John Cush RheumNow ( View Tweet)
Congratulations to 2025 Crafoord Prize (in Polyarthritis) laureates Christopher Goodnow, (UNSW Sydney, Australia), and David Nemazee (Scripss,, USA) for their work on tolerance checkpoints - prevent B cells from attacking the body’s own tissues in autoimmune diseases… https://t.co/WSyXVIFJa1 https://t.co/JtBau2JSvo
Dr. John Cush RheumNow ( View Tweet)
Full read review and overview of Fibromyalgia - manifestations, pathophysiology, treatments and guidelines. Multidisciplinary, patient-centered treatment should includes a combination of pharmacological and nonpharmacological options. https://t.co/Go5T9pN6wH https://t.co/CIXai9OhZd

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Dr. John Cush RheumNow ( View Tweet)
RHEUMS! Please check out this important Survey on Cannibis/THS/CBD use in Rheumatology. This is a short survey (Ive done it) from the Rheumatology Research Foundation, FORWARD and the National Databank folks. We need to know more here; especially from you1 Link:… https://t.co/0KYbgqvceq https://t.co/JeO8hV0luB
Dr. John Cush RheumNow ( View Tweet)
Screening for #RA-Machine learning algorithm applied to primary healthcare pts shown to correctly identify early RA based on 11 features (RF, CRP, ESR, SUA, HB, PLT, AMS, age, SJC TJC, deformity) w/ 96% specificity, 96% sensitivity, 96% AUC. https://t.co/Q25yvDwdJZ https://t.co/CTESAl6hSf

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Dr. John Cush RheumNow ( View Tweet)
🚨 Join us for the 7th Annual RheumNow Live 2/8 - 2/9 : Where Innovation Meets Impact in Rheumatology! 🚨 🗓 2025| In-Person & Virtual 💻 Virtual: Stream + Q&A access (spots still open!) Don’t miss the rheumatology event of the year! 👉 Register today:… https://t.co/Rf4U6JcdKs https://t.co/ilG2M7aRYS
Dr. John Cush RheumNow ( View Tweet)
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