Artificial intelligence isn’t a distant frontier anymore. It’s here, and it appears able to detect signs of rheumatoid arthritis, possibly before we can clinically detect it. Two studies presented at this year’s ACR meeting highlight just how close we may be to a future where algorithms flag disease before we can and monitor activity with minimal patient burden.
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New Insights into Pregnancy Outcomes and Maternal-Fetal Health in Rheumatic Diseases
ACR Press Release
At ACR Convergence 2025, the American College of Rheumatology presents new research illuminating critical challenges and advances in pregnancy outcomes for women living with rheumatic diseases, including axial spondyloarthritis, antiphospholipid syndrome, and lupus.
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Fatigue is one of the most disabling symptoms in psoriatic arthritis (PsA), yet its causes are often underexplored. At ACR 2025, Abstract #0549, a possible hidden contributor was studied: obstructive sleep apnea (OSA).
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With increased disease awareness and more regular, accessible testing for anti-neutrophil cytoplasmic antibodies (ANCA), ANCA-associated vasculitis (AAV) has become an increasingly recognized clinical entity in rheumatologic practice.
Janet Pope
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#Pros and #cons of #AI
Need to know both
Need to assess AI #quality and #accuracy
‘Assume AI WILL be used’
JHausmann
By trainees, patients and medical personnel
Train #faculty re #AI
#ACR25 @RheumNow @ACRheum
#26S17 https://t.co/CvPDQPbueW
David Liew
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Topical therapies in cutaneous lupus - find the right level
Victoria Werth #ACR25 SLE guideline session @RheumNow https://t.co/o3gBuFkr4n
Antoni Chan MD (Prof)
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High-resolution ultrasound detected subclinical enthesitis in 44% of psoriasis patients without arthritis and 12% had PD positivity. Supports a preclinical PsA phase and use of MSUS to detect entheseal inflammation in both symptomatic and asymptomatic PsO patients for timely
Janet Pope
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Don’t fight #AI
#RCTs - #AI better at soft
Skills alone
Vs
#Medical input and AI as we tend to
Disbelieve the model & mess it up!
#LLM can accurately take a #history
Bottom line EMBRACE AI ?check it too
#ACR25 @RheumNow @ACRheum
#artificial #intelligence and #medicine
26217 https://t.co/22MYD4QqzH
Wondering whether rheumatology is the specialty for you?
Dr Bryant England kicks off the clinical science #YearInReview with an impressive overview of what a year in rheumatology looks like.
New drugs, new devices, new disease names! 🤯
#ChooseRheumatology
#ACR25 @RheumNow https://t.co/uLrNFPgeAn
sheila
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#Sjogren disease is here to stay.
“The name has caught up to the science of SD and this can translate to better treatment outcomes for patients” - Dr. Bryant England
#ACR25 @RheumNow https://t.co/M4r0XXkswv
sheila
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Basic Sci Year in Review:
Dr. Anne Davidson discusses the potential pathologic link bet tryptophan, indole, I3S & IL-17 pathways.
I3S induces epidermal thickening in mice and correlated with dse activity in patients with #psoriasis
#ACR25 @RheumNow https://t.co/WNNbBBESQ3
Gabriela Martinez Zayas, MD
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From Eye on Cytokine Storm- Decoding MAS by Dr Grant Schulert : “IL-18 is highly elevated in SJIa and other autoinflammatory disorders…can amplify innate signaling as well as induce IFN-gamma”. @RheumNow #ACR2025 https://t.co/6e5yfeDepX
🔥 Hot off the press
Prof John Stone shares results from Phase 3 of REPLENISH, out only a few days ago, in which secukinumab met all primary endpoints in treatment of PMR.
https://t.co/RlcQWybKrR
#ACR25 @RheumNow https://t.co/ucNt2HxJpW
Antoni Chan MD (Prof)
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Great to be with team @RheumNow reporting on the latest from #ACR25 https://t.co/h941qYSc6U
REPLENISH - Secukinumab Works in Polymyalgia Rheumatica
Novartis announced the results of their REPLENISH trial showing the efficacy of secukinumab (Cosentyx) (SEC) in adults with polymyalgia rheumatica (PMR).
https://t.co/qa9RzmNFU4 https://t.co/dCEkelJzni
Colchicine Ineffective in Long COVID
Management of long COVID has been perplexing with symptoms having functional and possibly inflammatory origins. Colchicine has been studied in long COVID and failed to improve functional capacity, respiratory function, or inflammatory https://t.co/9E3dvUFqJP
Meniscal tears - Systematic review of 46 studies
- Incidence of 66 per 100,000
- Annual cost of 5 billion to US healthcare
- Trend to preserve the meniscus, do less removal, more preservation
- Biologic Rx (platelet-rich plasma & stem cell Rx) inconclusive results https://t.co/IPyRFad9GX
UK National Joint Registry study of 1.5 million TKR and THA (2010 to 2022); trends show median Length of hosp stay (LOS) decreased from 4.3d to 2.75 d for THR; & from 4.35d to 2.9d for TKR; & from 3.2d to 1.9d for UKR (unilat. knee replacement). Longer LOS with comorbidity, https://t.co/DNBZTPFRsl
Interleukin-18 (IL-18) regulates appetite, body weight & glucose homeostasis. IL-18 deficiency may lead to obesity, but chronic IL-18 signalling promotes liver fibrosis. IL-18 is Elevated in obesity and diabetes mellitus https://t.co/Xylvexqvtg https://t.co/sRutSCoLf9
From the plenary to posters, RheumNow is your companion for ACR Convergence 2025. Expect:
• KOL videos
• Clinical trial highlights
• Daily faculty recaps
• Live streaming
#ACR25 #Rheumatology #ClinicalTrials https://t.co/zZAwYINmC2
