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Celecoxib Lowers Colon Cancer Recurrence Risk

Jack Cush, MD

The Alliance for Clinical Trials in Oncology today announced the results of a data analysis from a randomized phase III clinical trial involving patients with stage III colon cancer, which found that adding the drug celecoxib

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Lifestyle diet alcohol risk obesity

Proinflammatory Diet Increases Gout Risk

MedPage Today

Some dietary habits are worse than others when it comes to gout risk for women, a large study indicated.

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Infectious Sacroiliitis

Jack Cush, MD

A large Chinese cohort study of patients with infectious sacroiliitis (SI) suggests that CT-guided biopsy of the sacroiliac joint is necessary to properly identify the infectious pathogen leading to SI.

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uveitis eye iritis

Adalimumab Withdrawal in Uveitis Patients

Jack Cush, MD

Adalimumab is an effective treatment for JIA-associated uveitis and has been FDA approved for such use - but for how long and can the drug be withdrawn? An adalimumab (ADA) withdrawal trial has shown recurrence of uveitis, arthritis, or both, when the disease was previously controlled on ADA.

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Weak Data (1.24.2025)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from RheumNow.com, and features Dr. Charity Dean, the Keynote speaker at RheumNow Live 2025, and why she is an inspiration.

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DMARDs,biologics,RA

Getting to Remission - Without Biologics

Jack Cush, MD

Analysis of data from two early rheumatoid arthritis (ERA) cohorts shows remission in RA is primarily seen in those who do not require biologic DMARDs (bDMARDs), while those needing bDMARDs are less apt to achieve remission.

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Do Rheumatologists Follow 2020 ACR Guidelines on Gout?

Jack Cush, MD

Schlessinger and colleagues report that US Rheumatologists generally adhere to and agree with the 2020 American College of Rheumatology (ACR) Guideline for the Management of Gout, although knowledge gaps and practice variance exists.

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Functional Precision Medicine in Rheumatoid Arthritis

Jack Cush, MD

Novel research from the Medical University of Vienna demonstrates the plausible utility of functional precision medicine using immunophenotyping of blood cells with rheumatoid arthritis, to help guide treatment selection.

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NHANES survey data on 2200 #RA pts shows dietary modification can yield reduced all-cause mortality risk. Diets w/ high Healthy Eating Index & low Dietary Inflammatory Index (DII) reduced mortality (HR 0.70; 95% CI: 0.53–0.92; adjusted P = 0.01) https://t.co/T77YQMvRQ2 https://t.co/WaCapITHGK

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Dr. John Cush RheumNow ( View Tweet)
German database shows since 2010, work participation has improved for rheum pts, reflected in higher employment, reduced absenteeism and less disability retirement. However, patients have not reached population employment rates. https://t.co/B8VKBgGNGe https://t.co/OOMNym3XrR

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Dr. John Cush RheumNow ( View Tweet)
Getting to Remission - Without Biologics Analysis of data from two early rheumatoid arthritis (ERA) cohorts shows remission in RA is primarily seen in those who do not require biologic DMARDs (bDMARDs), while those needing bDMARDs are less apt to achieve remission.… https://t.co/K1gUdEhk1n https://t.co/PHQafKPHpB
Dr. John Cush RheumNow ( View Tweet)
Cardiovascular Risk in Cutaneous Lupus Erythematosus A retrospective study of cutaneous lupus erythematosus (CLE) patients finds an increased risk of atherosclerotic cardiovascular disease (ASCVD) on par with systemic lupus patients. https://t.co/QimKD9klM2 https://t.co/2Yb0tWoOB0

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Dr. John Cush RheumNow ( View Tweet)
Metanalysis of 11 studies shows that curcumin (tumeric) can reduce pain, muscle damage and inflammation in athletes following vigorous physical exercise. "pre- and post-exercise curcumin consumption.. assoc w/ better outcomes in muscle recovery, pain & antioxidant capacity"… https://t.co/FZE2ugvvPK

Dr. John Cush RheumNow ( View Tweet)

Lung Involvement in Still's Disease A multicentre registry observational study assessed lung involvement in a cohort of Still’s disease patients, affirming pleuritis as most common and that parenchymal lung inflammatory disease is very uncommon in both children and adults.… https://t.co/rGYEgCeUDA https://t.co/fdUGvfU8HH
Dr. John Cush RheumNow ( View Tweet)
Cardiovascular Risk in Cutaneous Lupus Erythematosus A retrospective study of cutaneous lupus erythematosus (CLE) patients finds an increased risk of atherosclerotic cardiovascular disease (ASCVD) on par with systemic lupus patients. https://t.co/3gEkFBK8wc https://t.co/kagpp7w7nE

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Dr. John Cush RheumNow ( View Tweet)
RA higher risk of Celiac Dz -- Rheumatic Dz administrative data review (2004–2013)compared 70,061 #RA w/ 276,895 controls, median F/U 9 yrs. (IQR 9–9). Celiac Prevalence higher in RA (171/70,061 = 0.24% vs 398/276895 = 0.14%; p < 0.001), more so in females w/ RA… https://t.co/SayZYvkZpV https://t.co/fcuyJ5sFk0
Dr. John Cush RheumNow ( View Tweet)
Korean population-based study shows that from 2010 to 2023 prevalence of ank Spondylitis (AS) increased 27 per 100,000 (2010) to 82 per 100,000 (2023). Also increasing were # of pts >50 yrs (20-33%), #females (18-24%), Comorbidities, TNFi use (30-43%), while csDMARDs declined.… https://t.co/9NjU1IugaF https://t.co/kTCtIj2BjD
Dr. John Cush RheumNow ( View Tweet)
A substantial # of pts with inflammatory arthritis (IA) are not receiving adequate treatment for depression and anxiety(same as those IA-free controls). Canadian study of 6,951 w/ IA & depression, on 50% recv treatment & 20% psych. Rx for depression. Similar for 3,701 w/ IA &… https://t.co/CfpwEtLH3c

Dr. John Cush RheumNow ( View Tweet)

Metanalysis of 11 studies shows that curcumin (tumeric) can reduce pain, muscle damage and inflammation in athletes following vigorous physical exercise. "pre- and post-exercise curcumin consumption.. assoc w/ better outcomes in muscle recovery, pain & antioxidant capacity"… https://t.co/J07UId683Y

Dr. John Cush RheumNow ( View Tweet)

Lung Involvement in Still's Disease A multicentre registry observational study assessed lung involvement in a cohort of Still’s disease patients, affirming pleuritis as most common and that parenchymal lung inflammatory disease is very uncommon in both children and adults.… https://t.co/bUvg4xQrsr https://t.co/fz7wiNU0Xx
Dr. John Cush RheumNow ( View Tweet)
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