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ACR20 – Day 1 Report
Friday was the first full day of scientific sessions at the 2020 Virtual ACR/ARP annual meeting. Here are my highlights from day one:
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Do you obtain baseline and/or serial TTE, EKG, BNP, and TROPONIN* on follow-up visits of your patients with myositis? #ACR20 @RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Do you obtain baseline and/or serial TTE, EKG, and BNP on follow-up visits of your patients with myositis? #ACR20 @RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
@RichardPAConway @DrDDRheum @DrErickZamora1 @hoffmann_vold @RheumNow YES! Why? 'Normal' echo in 1/3 of patients with early PAH. Screening# Diagnosis. Below is data where echo and RHC was done at the same time. in those with eRVSP < 36, 36% had RHC- derived PAH. https://t.co/W2YiyZnwwV
Dr. Dinesh Khanna sclerodermaUM ( View Tweet)
Dr Cai presents risk of CVD in gout in study 450,000 patients. Gout was independently associated with an increased risk of CVD events HR = 1.24 for women; 1.21 for men. @rheumnow #ACR20 Abstr#950 #ACRbest https://t.co/089aKtN5a7
Richard Conway RichardPAConway ( View Tweet)
Rheumatoid arthritis and lung disease in the spotlight at #ACR20 by @jeffsparks
https://t.co/0Dth0k6uve https://t.co/pGfGtq8Sz7
Links:
Dr. John Cush RheumNow ( View Tweet)
Nice insights into RA-ILD from @jeffsparks:
- assoc (in Medicare): male, smoker, asthma/COPD, b/tsDMARDs, steroids
- mortality risk? Yes, esp resp (sdHR 4.4), cancer
- ACPA/lung inflamm related to RA-ILD? Yes, esp anti-filaggrin (aOR 3.08/log unit)
#ACR20 ABST0489/0490 @RheumNow https://t.co/DGkNNPOcbd
David Liew drdavidliew ( View Tweet)
Dr Sammy Zakaria said we need close communication with cardiologist in myocarditis related to myositis. #ACR20 @RheumNow https://t.co/kTAZKWpw0S
Sole RetamozoSole ( View Tweet)
Does your pt have myocardial inflamm? Trop specific but not sensitive, BNP neither sens or specific. Consider EKG - sensitive (85%), but non-specific- But TTE is essential and cMRI is best! #ACR20 @RheumNow Great lecture from cardiologist, @HopkinsBayview APD https://t.co/6THm37KbQ3
Eric Dein ejdein1 ( View Tweet)
Most ignore pharmacists annoying faxes re safety of QT interval with #hydroxycholoroquine likely the right thing to do! @RheumNow #ACR2020 @CRASCRRheum abstr#431. https://t.co/pXBIDOV2MP
Janet Pope Janetbirdope ( View Tweet)
In the search for biomarkers in PsA, interesting study showing absolute lymphocyte count is negatively correlated with cardiovascular disease risk score and red cell distribution width and increases with TNF-Inhibitor Therapy @rheumnow #ACR20 Abstr#878
Dr. Antoni Chan synovialjoints ( View Tweet)
Year in review by @JYazdanyMD ENTRACTE trial: CV safety of TCZ vs. ETN >similar CV events >TCZ grp slightly more infections & GI perforations @RheumNow #ACR20 https://t.co/yBDeHBDB3Z
sheila RHEUMarampa ( View Tweet)
Lung disease in primary #SjogrensSyndrome is common; both conditions were diagnosed at the same time in 43% of patients, found an #ACR20 study from @joannamarco @GGRheumdoc + @UW @uofcincy colleagues. “Close monitoring is warranted” to make sure lung function is not declining. https://t.co/MpA0Rq2uVR
CreakyJoints.org CreakyJoints ( View Tweet)
UK Biobank data: RA is associated with not just restrictive but also *obstructive* patterns on spirometry/PFTs (independent of smoking).
Consistent observation; direction of causality? The lung in RA continues to fascinate.
Prisco @jeffsparks et al #ACR20 ABST0491 @RheumNow https://t.co/LcjtAefnVF
David Liew drdavidliew ( View Tweet)
ILD in SSc has grave consequences. Abstr#393 Claims database in Ontario shows relevant Scleroderma ILD occurred in 17% of >3000 pts with nearly double the mortality #ACR20 @RheumNow @CRASCRRheum #bestinclass https://t.co/K3UXvuxBcp
Janet Pope Janetbirdope ( View Tweet)
#ACR20 Abstr#0433 #PlenaryACR Georgia SLE registry 336 pts ⬆️stroke/isch heart dz with:
👉3X stroke risk and 24X IHD risk for black pts
👉predictors stroke: black race, DLE, renal dz
👉predictors IHD: age>65, black race, neuro & immuno d/o (e.g, APAs)
@RheumNow https://t.co/u6Ky7r0FYF
k dao KDAO2011 ( View Tweet)
Plenary session 1 no#2F011 #ACR20 @rheumnow
Black #SLE patients have a 3 fold higher stroke and 24 fold higher Ishemic Heart Disease risk! https://t.co/AYtiXk7pDa
Bella Mehta bella_mehta ( View Tweet)
Dr Fernandez-Diaz on abatacept in RA-ILD in 263 patients. Abatacept appears safe and effective. Equivalent to RTX. Good option as s/c admin @rheumnow #ACR20 Abstr#0233 #ACRbest https://t.co/LfjqZpnGCh
Richard Conway RichardPAConway ( View Tweet)
When prescribing hydroxychloroquine for RA, SLE, or other rheumatic diseases, do you routinely order an EKG (either before or during)? #ACR20 @RheumNow
David Liew drdavidliew ( View Tweet)
Using #MachineLearning, multimorbidity patterns predominant for #rheumatoid arthritis: cardiometabolic, cardiopulmonary & #Mentalhealth/pain disorders. Patterns similar to non-RA pts but prevalence higher in RA pts. @RheumNow #ACR20 abstr#0179 https://t.co/zfCxzKquDV
sheila RHEUMarampa ( View Tweet)
