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5 yr multinational PROOF study - enrolled 1612 axSpA pts enrolled (65% xray+ axSpA; 35% nr-axSpA) nraxSpA had more enthesitis, PSO IBD. Over time, more TNFi use (less NSAIDs) w/ less disease activity #ACR21 Abst #0363 https://t.co/5DdDlCjq9h (Graph: NSAID use over time) https://t.co/5JE69vTIy9

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Dr. John Cush RheumNow ( View Tweet)
Quick plug: not all joint pain in ICI-treated pts needs reflex steroids eg OA can get exacerbated by ICI Rx (ICI-aOA) call rheum, hold the PNL & save tumor response @ReidMDMPH @got_rheum @lovetolearn27 +me #ACR21 ABST1518 @RheumNow our paper @jitcancer https://t.co/InespbOn6m https://t.co/HSjtGrwePE

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David Liew drdavidliew ( View Tweet)
Glory to GLORIA trial? Low dose prednisone 2mg in active RA>65yrs, N=451 All Standard care. in 2yrs, ~40% drop out- same in each grp Better RA control but NNH 9.5 w steroids, mostly non severe infections. So, prednisone debate in RA continues #ACR21 @RheumNow #ACRBest abst#1678 https://t.co/emOaYSjYAa
Janet Pope Janetbirdope ( View Tweet)
Pregnant pts w/ PsA, but not AxSpA, at increased risk of pre-eclampsia. In RA pregnancies, pre-eclampsia risk increases w/ dz severity prior/during pregnancy. We need to discuss potential risks w/ pts and OB team. Abs 1722 #ACR21 #RheumNow @RheumNow https://t.co/yeQmNAZ1jV https://t.co/cBfeVKQHfr

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Dr. Rachel Tate uptoTate ( View Tweet)
Just worthwhile remembering: in terms of TNFi anti-drug immunogenicity in autoimmune disease: RA is top of the pops (although dose spacing is worse) data from NOR-DRUM A, TDM in infliximab #ACR21 ABST1525 @RheumNow https://t.co/wfcA72wcLP https://t.co/mHppH6qYdY

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David Liew drdavidliew ( View Tweet)
ANA negative SLE! Lunch w/Dr. John P Atkinson. When I was in training @WUSTLrheum he bet that if you come across a case of ANA neg- SLE that is convincing, he will buy lunch. Great case of SLE following spont coronary artery dissection. #ThievesMarket #ACR21 Abst#TM18 @rheumnow https://t.co/TRyQaJ4kbR
TheDaoIndex KDAO2011 ( View Tweet)
Fun things at #ACR21. Abs1186 #Kardashian index: K-index = # of followers on Twitter/expected # of followers based on citations. ⭐️Only 1 program director (PD) had K-index>5, an "academic Kardashian" ⭐️Only 11 PDs on Twitter had >100 followers https://t.co/uH408ri5nY @Rheumnow https://t.co/d8VeyzAIcU

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Eric Dein ericdeinmd ( View Tweet)
Impressive case of vasculitis – should be part of @ACRheum image bank #ThievesMarket #ACR21 Abst#TM20 @rheumnow https://t.co/YiBikROuzb
TheDaoIndex KDAO2011 ( View Tweet)
They are the up and coming leaders in our field! I got to interview them about 👉🏼why #GeriRheum is important (our pts are aging) 👉🏼small changes to your practice for big outcomes 👉🏼Tips: pain control/funx #acr21 @UnaMakris @RheumNow https://t.co/f71L0P3foE via @YouTube

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TheDaoIndex KDAO2011 ( View Tweet)

Pirfenidone in RA-ILD, TRAIL-1 study. Long-awaited. Early termination due to COVID led to under-powering. Slowed decline in FVC, especially in UIP pattern. Seemed to have less adverse events than we see with nintedanib. Abstr#L10 #ACR21 @RheumNow https://t.co/sYRDhG3u4y
Richard Conway RichardPAConway ( View Tweet)
Artificial neural network showed good generalizability and a high specificity with acceptable sensitivity in the detection of radiographic sacroiliitis. A tool for interpretation of sacroiliac radiographs as a part of the diagnostic approach @RheumNow #ACR21 Abst#1919 #ACRbest https://t.co/SdmomEWwya
Dr. Antoni Chan synovialjoints ( View Tweet)
New dimensions in cellular immunology. Great session, some which I understood. Kids with #JIA have more cytolytic pathway missense - some leads to macrophage activation syndrome #MAS Low NK cells in Juvenile Dermatomyositis. 9T112 #ACR21 @RheumNow https://t.co/5lUkqr65UM
Janet Pope Janetbirdope ( View Tweet)
Adipokines in RA ⚡️Highest Quartile Adiponectin associated w/ ⬆️ all-cause mortality HR 1.46 ⬆️ CV mortality HR 1.85 ⚡️Highest Quartile Leptine ⬆️ 25% all-cause mortality #ACR21 #Abst1645 @RheumNow https://t.co/O1NAbfMvif https://t.co/VVdgZHP1j5

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Aurelie Najm AurelieRheumo ( View Tweet)
No clear excess risk for offspring exposed in-utero to, VED or TNFi's. UST showed infection signal BUT w/ wide CIs. We need more research re: biologics and placental transmission potential/subsequent risks. Abs 1713 #ACR21 #RheumNow #ACRbest @RheumNow https://t.co/W3K5uDyHlC

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Dr. Rachel Tate uptoTate ( View Tweet)

b/tsDMARDs + tumor response in rheum irAEs Excellent point by @CCalabreseDO @LCalabreseDO: - despite progression in 5/10, DMARD contribution uncertain (bad cancer) - without DMARD, ICI would have had to stop crucial question, prospective study needed #ACR21 ABST1519 @RheumNow https://t.co/omJnTNVscH
David Liew drdavidliew ( View Tweet)
The wave of the future? Study details immune profile which discriminates PsA from PsO using phenotyping of serum immune cell subsets & machine learning. Abs 1774 #ACR21 #RheumNow #ACRbest @RheumNow https://t.co/huNTY3IdRf https://t.co/3aW64pb9UW

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Dr. Rachel Tate uptoTate ( View Tweet)
Great case where the #COVIDvaccine was blamed, but he had a diet of doughnuts, steak&cheese sandwiches w/snack cakes, and popsicles. #ThievesMarket #ACR21 @rheumnow https://t.co/J78Nw5NhKs
TheDaoIndex KDAO2011 ( View Tweet)
The #ACR21 Playbook This playbook is designed to help you navigate a truly big meeting (with >2000 presentations and over 15,000 attendees from over 100+ countries). What follows is based on experience and the acquired insights our peers. https://t.co/GlDOnVfHsc https://t.co/RQlM2fjCzY

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Dr. John Cush RheumNow ( View Tweet)
Autoantibodies are underrated in rheumatic irAEs (?B cells in general), but probably not your usual. If Ab are of interest, suspect we're going to have to look at non-classical ones Elegant from @NilashaGhosh @MPostow @got_rheum @lovetolearn27 #ACR21 ABST1520 ABST1521 @RheumNow https://t.co/tLSJOZw1YG
David Liew drdavidliew ( View Tweet)
Great conversation with @BayviewMedicine @jhrheumatology alum Dr. Jason Liebowitz and Professor Janet Zeide on "Gift of Gab"- communications skills for the rheumatologist at #ACR21! @Rheumnow https://t.co/O1u3X8urag

Eric Dein ericdeinmd ( View Tweet)

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