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Post hoc analysis of BLISS-LN 🦋
Pts who didn't receive steroid pulses at induction 👇
🔸⬆ PERR & CRR responders, ⬇mean daily pred doses, more pts had ave daily pred <=5mg or <=7.5mg for both BEL & PBO
🔸BEL grp ⬇ flares/kidney-related death
@RheumNow #ACR21 #ACRBest abs1461 https://t.co/ev0LK7d6oL
sheila RHEUMarampa ( View Tweet)
Dr. Furie asked Dr. Touma what he was doing in 1976? Dr. Touma said, "I was not even in school, yet." Dr. Furie noted that in 1976, the first study was published on methylprednisolone pulse for lupus nephritis in 7 patients. #ACR21 @rheumnow Link below https://t.co/Oe9xmH7Tzg https://t.co/xslAHYNXej
TheDaoIndex KDAO2011 ( View Tweet)
#ACR21 Ab#1166. How many of your pts use marijuana?
⭐️Probably more than you think!
▶️57% have tried, >50% use at least weekly
▶️67% doctors thought <20% of pts use it
🔥Pts over 40 yo MORE likely to report marijuana use
@Rheumnow https://t.co/0uW8rZvf1k https://t.co/ShMnR0faHr
Links:
Eric Dein ericdeinmd ( View Tweet)
#ACR21 #Abstr1461 Post-hoc analyses from BLISS-LN #lupus showed independent of IV Steroid pulses during induction, at Wk104:
💠More pts in Belimumab achieved PERR and CR vs PBO
💠More pts in PBO had flares and kidney event/death vs BEL
@RheumNow https://t.co/pLxAI2RDRJ https://t.co/8CZMq3RTls
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Lianne Gensler presenting "Exercise Strategies for Ankylosing Spondylitis". Not all physical activity is similarly beneficial. Learn more now by attending her session at #ACR21!
@CherylKoehn @ArthritisNetwrk @EIM_Canada @exerciseworks @PhysioKTBroker @jwhittak_physio @JasminKMa https://t.co/rER3EdCohO
JointHealth ACEJointHealth ( View Tweet)
@rheum_cat I want to run into an ASAS meeting and shout "seronegative spondyoarthropathy"! https://t.co/WkEz5BMttJ
Richard Conway RichardPAConway ( View Tweet)
@LianneGensler Is exercise anti-inflammatory?
In this study, healthy volunteers were infused with E coli endotoxin 😲 and their TNF levels measured. TNF levels were compared between groups at rest and groups exercising.
TNF levels were ⬇ by exercise.
#ACR21 https://t.co/Ylw7SQX32y
Rheum Cat rheum_cat ( View Tweet)
@rheum_cat @alhkim You're beating @RheumNow, quite impressive @rheum_cat !
LauraCoates DrLauraCoates ( View Tweet)
MRI Imaging in RA and SpA: Dr. Sheila Reyes ( @RHEUMarampa)
Dr. Sheila Reyes discusses abstracts #0468 and #0469, presented at the #ACR21 annual meeting.
https://t.co/MeVia60BNa https://t.co/WRgCifpioQ
Links:
Dr. John Cush RheumNow ( View Tweet)
#ACR21
#SLE #COVID19
Use of Telemedicine for follow-up of SLE in COVID19
Wait times lower for telemedicine
Patient satisfaction higher in telemedicine group
More hospitalization, higher switch to in person follow up in telemedicine https://t.co/Y21Vki1uDP
Dr. Laura Lewandowski LauraLewMad11 ( View Tweet)
#ACR21
#SLE
SLE – Treatment: New Agents, Old Agents
Pooled data from 2 phase 3 trials (TULIP 1 and 2)
⏬LLDAS is an attainable T2T endpoint in adult SLE trials
⏬Anifrolumab treatment associated with earlier and more sustained LLDAS in adult SLE https://t.co/bxGlVsJOZC
Dr. Laura Lewandowski LauraLewMad11 ( View Tweet)
1) Trial enrollees were likely partial/non responders to MMF at baseline (NIN had clean slate)
2) Unblinding from diarrhea from NIN, likely tilts toward NIN d/t PLBO effect
3) MMF-PLBO may have had dx longer than NIN-PLBO, missed critical early window to affect progression?
Mike Putman EBRheum ( View Tweet)
Interesting thoughts from Dr. Distler re:nintedanib & MMF in SSc-ILD
Agree we should look into MMF-nintedanib combo, but this graph makes me think MMF > NIN
Why would that be? Unlike NIN, MMF pts were NOT randomized, which likely favors NIN for a few (speculative) reasons: https://t.co/ZHBD8x74PM
Mike Putman EBRheum ( View Tweet)
ACR Convergence 2021 attendees – join us this evening, Monday, Nov. 8, from 6:00 to 6:30 PM ET, for the virtual #ACR21 Tweet Up! Add to your agenda → https://t.co/lisFBp1scO #RheumTwitter https://t.co/3pO3quH2Sm
Links:
American College of Rheumatology ACRheum ( View Tweet)
Hard to keep up with all the good news.
Congrats to @philseo, Program Director extraordinaire and Director of the Johns Hopkins Vasculitis Clinic, for receiving the ACR Distinguished Clinician Scholar Award.
#ACR21 @HopkinsMedicine @HopkinsMedNews https://t.co/FQb2W6KpYT
Max 🦖 MaxKonigMD ( View Tweet)
8M415 Gout Imaging Advances: Ralf Thiele on US🔊and DECT
US>DECT: DECT needs a minimal density of MSU; DCS, tophi <2mm, liquid tophi may not be detected; US can show hyperemia
DECT>US: DECT can show areas that may be overlooked from standard protocols
💡Bonus:stay around for Q&A https://t.co/G7yQaj9fHw
USSONAR USSONAR_Rh ( View Tweet)
🔥Continued, More Clinically Meaningful data in #SSc #ILD from #Nintedanib in >52 wk SENSCIS & SENSCIS-ON(open-label ext)#ACR21 Dr Distler
✨MMF likely to stay 1st line, then Nintedanib
❓Is it time for MMF + Antifibrotic upfront??
Await SLS-III;Data so far seems supportive https://t.co/JWXMlsJgmc
Ashima Makol MD AshimaMakol ( View Tweet)
Great Q&A re:VEXAS w/Marcela Ferrada
When to suspect VEXAS? Male, MCV >100, Plt <200
Can you order genetics yourself? No. 😆
Any IMT that works? Require high dose steroid, partial response to TCZ, needs close f/u d/t possible neutropenia!
How to refer to NIH? Slide!!! ⬇️⬇️ https://t.co/UvUCFbvX2r
Mike Putman EBRheum ( View Tweet)
Tribute #RheumPix to a special time in San Fran for ACR 2015 w/ my dear Father,Dr. Kamal M. El Ramahi, MD, FACR -may he Rest in Peace. I was an IM Res then not yet settled on a specialty when he sweetly invited me...the Rheum seed began its blossom
#ACR21
https://t.co/cp4eFCbTWl https://t.co/ayKAPi0WA2
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
A study at #ACR21 by Charite-University Medicine Berlin researchers suggests taking tumor necrosis factor inhibitor (TNFi) #biologics earlier in the course of disease could slow down spinal progression in #AxialSpondyloarthritis patients. https://t.co/lDkaMkOcez
CreakyJoints.org CreakyJoints ( View Tweet)