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Trauma associates with subsequent increased flares of SLE. Abstr#1446 #ACR21 @RheumNow https://t.co/QeNXOjHAjn
Richard Conway RichardPAConway ( View Tweet)
Tell me there's no collegiality on the #ACR21 virtual platform!
kudos to @ACRheum for making this thing run so smoothly, year-on-year
(and I'm telling you, the value's in the chat and the questions)
@RheumNow @Janetbirdope https://t.co/XJZArHIdnc
David Liew drdavidliew ( View Tweet)
Can you win the JAK pot twice? Equal effectiveness of JAK to JAK in #RheumatoidArthritis vs JAK to bDMARD. If d/c due to AE w JAK seemed to recur w 2nd JAK. Not RCT ?Channeling bias. But JAKi were worse off at baseline but did= switch v swap #ACR21 #ACRBest abst#1442 @RheumNow https://t.co/SRXMHdUBJF
Janet Pope Janetbirdope ( View Tweet)
Dr Jafarzadeh @Tuhina_Neogi on association NSAID use with TKR. At same level of pain, NSAID users appear to have more TKR. Is this same phenomenon we see with IA steroids (and tanezumab?)⬇️pain⬆️use⬆️damage? Abstr#1447 #ACR21 @RheumNow https://t.co/oY2ckmui0D
Richard Conway RichardPAConway ( View Tweet)
Long-term follow up of REDO study of ultra-low dose RTX (200mg vs 500mg vs 1000mg every 6 months) in RA. All doses appeared similarly effective, but also had similar adverse events. Potentially cost and time saving. Abstr#1443 #ACR21 @RheumNow https://t.co/0FRYPUOMpY
Richard Conway RichardPAConway ( View Tweet)
#ACR21 Ab#1443 by @NathandBroeder: Ultra-low dose RTX in RA?
⭐️RTX 200mg
▶️High retention in all groups- only 7 pts (6%) switched therapy. No diff in disease activity bw 200/500/1000mg
Great initial data, want more data on CD19/20, Ifns, etc.
@Rheumnow https://t.co/6UNUVh5ZW8 https://t.co/X1jCcw3h0I
Links:
Eric Dein ericdeinmd ( View Tweet)
?Save $ and ⬇️bad #COVID19 outcomes by using ultra low dose #Rituximab in #RheumatoidArthritis retreatmet after responding to 1g. Not quite same benefit and sl earlier repeat dosing. @RheumNow #ACR21 #ACRBest abst#1443 Impt study https://t.co/SFZKpTYJXP
Janet Pope Janetbirdope ( View Tweet)
Way to go Texas!
#ACRknowledgebowl winners #GullsofGalveston when they answered the final jeopardy round: This monogenic dz can mimic Behcet’s syndrome and occurs due to mutation in TNFAIP3 @utmbhealth #ACR21 @rheumnow
...What is ...Haploinsufficiency A20? https://t.co/ExjKqtykVy
TheDaoIndex KDAO2011 ( View Tweet)
Dr Sherbini @james_gwinnutt @khyrich on baseline factors associated with nausea and alopecia with MTX. Alcohol use (modifiable!) and 👩 assoc with both. Disease activity with nausea. HAQ with alopecia. Abstr#1444 #ACR21 @RheumNow #ACRBest https://t.co/e0BG9omnEv
Richard Conway RichardPAConway ( View Tweet)
axSpA and Depression
71 axSpA patients surveyed
Abnormal HADs-D scores ▶️Significantly worse BASDAI and AQoL scores
Severe PHQ-9 scores ▶️worse BASDAI, BASFI and ASQoL
Abst# 1305 #ACR21 @RheumNow https://t.co/Sf2Rm6z7ln
swethaann23 swethaann23 ( View Tweet)
#ACR21 Ab#1444 @AhmadSherbini. Factors ass w/ nausea & alopecia in MTX
⭐️Nausea & alopecia: ♀️, 🥃, activity score are risk factors
▶️EtOH highlights importance of folic acid in these pts!
@Rheumnow https://t.co/6UNUVh5ZW8 https://t.co/lxB2z2lXtu
Links:
Eric Dein ericdeinmd ( View Tweet)
Rheumatology Research Foundation Lecture: Learning lessons from @Google to harness #omics to better understand #RA
#ACR21 @RheumNow @RheumResearch https://t.co/NVAe2Rqo1O
Mrinalini Dey DrMiniDey ( View Tweet)
Love-hate relationship with #methotrexate. Side effects are common ex nausea/GI in 1/3 and alopecia in women. ?if you ask do you get more AES. Tough to treat especially SEs are early. ?Coach pt to help w persistence abst1444# @RheumNow #ACR21 https://t.co/NDQDVz8lk2
Janet Pope Janetbirdope ( View Tweet)
Dr Stewart @TonyMerriman2 report in 16,000 patients that repeat serum urate testing not superior to single measure in predicting incident gout over 9 years. Makes sense in general, maybe different in those with medication changes etc? Abstr#1449 #ACR21 @RheumNow https://t.co/69NofMNuB8
Richard Conway RichardPAConway ( View Tweet)
@NamrataRheum on outcomes in RA patients on RTX who get COVID-19. ⬆️hospitalisation, ICU, mech ventilation, but not mortality (in this cohort) Abstr#1445 #ACR21 @RheumNow https://t.co/8RcrzTdEb0
Richard Conway RichardPAConway ( View Tweet)
Guselkumab treatment of PsA improved Hgb levels and ⬇️ incidence of anemia
⭐️Anemia resolution associated with improved clinical status
#ACR21
#ACRBest
Abs#1331
@RheumNow
https://t.co/nbG7DpMDaR https://t.co/rxWsVfNqed
Robert B Chao, MD doctorRBC ( View Tweet)
#Uveitis is the most ⬆ freq xtra-articular manifestation in axSpA.
What factors are assoc'd w/AAU attacks?
👁🗨Active disease
👁🗨History of AAU
Bottomline: Treat axSpA, treat uveitis = better outcomes.
@RheumNow #ACR21 abs1314 https://t.co/O0kHulwJoP
sheila RHEUMarampa ( View Tweet)
#ACR21 Ab#1445. RTX & #covid19 outcomes
⭐️RTX ass. w/ ⬆️ COVID hospitalization, ICU admission, and ventilation
▶️ We need huge caution in pts that have not been vax'ed before RTX 💉💉
@Rheumnow https://t.co/6UNUVh5ZW8 https://t.co/R7jNb066m6
Links:
Eric Dein ericdeinmd ( View Tweet)
Yup, another large database shows more #hospitalizations with #RheumatoidArthritis with #rituximab but NOT higher mortality in matched analysis. Abst#1445 #ACR21 @RheumNow https://t.co/9XV8iX10sA
Janet Pope Janetbirdope ( View Tweet)
axSpA and Uveitis
Uveitis
🔼 in HLA-B27; Disease duration; Latin American pts
🔽 in Psoriasis
⭐️Uveitis was not significantly different in axSpA vs pSpA
Recurrent Uveitis
🔼disease duration and body mass index (BMI)
Abst #1307 #ACR21 @Rheumnow https://t.co/QDg8tOPgir
swethaann23 swethaann23 ( View Tweet)