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#PJP prophylaxis debate at #lupus hub if on #prednisone + immune suppression. #SLE has ⤴️septra side effects. Don’t know right answer. NNT v NNH is unknown. I don’t use it in #SLE. @RheumNow #ACR21 8M212
Janet Pope Janetbirdope ( View Tweet)
Post-hoc analysis of Deucravacitinib (TYK2i) for tx of PsA showed similar efficacy in pts with and without background csDMARD use.
⭐️>60% w/ background csDMARD use, majority of which was MTX
⭐️no difference in AE
#ACR21
Abs#1352
@RheumNow
https://t.co/nIJT7rNkJP https://t.co/bq0x1Ywguo
Robert B Chao, MD doctorRBC ( View Tweet)
Wonderful interview @KDAO2011 and @alhkim with great learning points on #BCell #Immunology
#ACR21 @RheumNow https://t.co/1292FNZanL
Akhil Sood MD AkhilSoodMD ( View Tweet)
Does #baricitinib affect #fatigue in RA patients?
👉🏼Results from RA-BEAM and RA-BEACON
👉🏼4mg baricitinib significantly reduced fatigue, starting week 16, compared to placebo
👉🏼Effect independent of disease activity in active RA
Abs#1235 #ACR21 @RheumNow
https://t.co/0SKhUKJHd7 https://t.co/R76wc56u6I
Mrinalini Dey DrMiniDey ( View Tweet)
Go @utmbhealth!
Final Round Knowledge Bowl #ACR21 @RheumNow
@UTMBInternalMed #DanielGonzalez #AparnaDas https://t.co/nQRn3s7J21
Akhil Sood MD AkhilSoodMD ( View Tweet)
Abst 1550 #acr21 @RheumNow @bryan_neel rheum pts after covid 19 vaccine: 18.9% reported SEs after the 1st dose,33.1% after 2nd dose. most frequent SEs fever, HA, fatigue & arthromyalgia. All mild&self resolved. Disease flare in 1/180 pts (0.6%) 1st dose 4/118 (3.4%) 2nd dose https://t.co/5AB5CJfYt8
Olga Petryna DrPetryna ( View Tweet)
Do you use #septa in #renal #lupus if on high dose prednisone? @RheumNow #ACR21 8M212 lupus hub
Janet Pope Janetbirdope ( View Tweet)
After that fantastic Plenary III, we need a well-deserved timeout and time for stretching 🙆🏻♂️ 🙆♀️! #wellness #ACR21 #RheumPix #RheumNow https://t.co/krF5tPAxsE
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#ACR21 Knowledge Bowl - Enjoy the farmer's market!
--> Cauliflower ears, cherries for gout, alfalfa and SLE... and of course anti-OJ myositis
@Rheumnow https://t.co/K8aG1IKYCu
Eric Dein ericdeinmd ( View Tweet)
#SLE study hub re #Lupus nephritis rocks. #Rituximab ⬇️antiDNA but then rebound ⤴️. Thus design of adding #belimumab to Rituximab=Less flares. Love the Hubs. #ACR21 @RheumNow https://t.co/MAhxJdmkWO 10.7326/M21-2078 #ACRBest https://t.co/qWPk5x1ZtM
Janet Pope Janetbirdope ( View Tweet)
Younger age, male gender, geographic region, lower weight and BMI, dactylitis+ or enthesitis+, lower scores Pt-Pain, PtGA, TJC and HAQ-DI were baseline predictors for achieving MDA and DAPSA LDA at Week 56 in UPA treated patients @RheumNow #ACR21 Abst#1348 https://t.co/FSXarBoBM1 https://t.co/UMCjr6eCRm
Dr. Antoni Chan synovialjoints ( View Tweet)
#ACR21 Ab#1029 - Great poster by Dr. Guttmann, IRAD in Summit NJ:
▶️2019 EULAR/ACR SLE criteria vs to 1997 ACR & SLICC
⭐️64% SLE pts: all 3 criteria. 10% only SLICC, 3% '97 ACR, 2% EULAR/ACR
⭐️Simliar gender, racial disparities to prior criteria
@Rheumnow https://t.co/QzG78HJgw5 https://t.co/eyuYhj4Acf
Links:
Eric Dein ericdeinmd ( View Tweet)
Almost like real-life, I've "run across the conference centre" to catch the end of the #InterstitialLungDisease session- some excellent insights from Dr Melissa Griffith on a complex topic, will definitely be reviewing the full talk later.
#ACR21 @RheumNow https://t.co/LdhXI8LLqY
Mrinalini Dey DrMiniDey ( View Tweet)
#ACR21 Abst#1029 @Rheumnow https://t.co/QzG78HJgw5
What is your preferred SLE classification criteria?
Links:
Eric Dein ericdeinmd ( View Tweet)
#ILD in #rheumatic diseases. When to use #glucocorticoids and immune suppressive sand anti fibrotic. V clear but harder in real world! @RheumNow #ACR21 #ACRBest https://t.co/R4V5ZggRsu
Janet Pope Janetbirdope ( View Tweet)
Steroids can cause co-morbidities which increase CV risk, but can PNL directly increase CV event (MACE) risk in RA?
30d PNL➡️15% increase in MACE in next 30d
(independent of underlying CV risk, RA dx activity)
PNL actively confers risk!
@BethIWallace #ACR21 ABST1428 @RheumNow https://t.co/cuL69n7cx3
David Liew drdavidliew ( View Tweet)
#ACR21 Abs:#1429: ALPN-303: Dual BAFF/APRIL antagonist for SLE:
⭐️Encouraging immunomodulatory activity and efficacy in animal models. ⬇️ Plasma cells and Ig secretions in vitro & vivo
⭐️Well-tolerated in animals w/o adverse events
🔥Phase 1 study in healthy volunteers!
@Rheumnow
Eric Dein ericdeinmd ( View Tweet)
Physical exercise did not increase BME disease in SIJ and spine in PsA. The risk of increased BME after 11 weeks of HIIT was not higher compared to controls in a cohort of PsA patients with low to moderate disease activity @RheumNow #ACR21 Abst#1362 https://t.co/DHj4D5Ojb1 https://t.co/J4KV5zdpey
Dr. Antoni Chan synovialjoints ( View Tweet)
Abst1424 #ACR2021 @RheumNow study of SEC in children w/ERA or JPsA : 72% reduced flare risk. Improved JADAS-27 score in both the ERA and JPsA categories. ⬇️ disease activity, enthesitis count & joints with active arthritis. adverse events & serious AEs in the SEC & PBO comparable https://t.co/J4MdxeYxWZ
Olga Petryna DrPetryna ( View Tweet)
What predicts response to MTX in RA?
👉🏼DAS28-ESR
👉🏼RA duration
👉🏼Pt global assessment
👉🏼Swollen joint count
Abs#1227 #ACR21 @RheumNow
https://t.co/s942zvFiZ1
Mrinalini Dey DrMiniDey ( View Tweet)