Predicting Cardiovascular Events in SLE Save
A study from the Georgia Lupus Registry shows that systemic lupus erythematosus (SLE) patients are at greatest risk for cardiovascular disease (CVD) events between years 2 and 11 after diagnosis and higher in Black people or those with a discoid rash.
This study assessed the timing and predictors of incident CVD in a predominantly Black SLE cohort drawn from the population-based Georgia Lupus Registry.
The study included a total of 336 SLE patients, 253 (75%) were Black and 56 (17%) had an incident CVD event with the greatest risk between years 2 and 11 after SLE diagnosis. Overall SLE patients had a 7-fold higher risk of incident CVD over the 15-year followup period. This risk was 19-fold higher in the first 12 years in Black people as compared to non-Blacks with SLE.
Black people with SLE and those with discoid rash (HR 3.2, 95% CI 1.4-7.1) had a significantly higher risk of incident CVD events.
Racial disparities contribute to morbidity and mortality risks with SLE.
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