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An estimated 100,000 to 120,000 fragility fractures occur annually in the Netherlands, the equivalent of at least 11 broken bones per hour.
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Can something as simple as a cup of coffee with milk have an anti-inflammatory effect in humans? Apparently so, according to a new study from the University of Copenhagen. A combination of proteins and antioxidants doubles the anti-inflammatory properties.
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A group of researchers from the Graduate School of Medicine at Nagoya University in Japan have discovered the impact of microRNA (miRNA) on inflammation in lupus in mice.
Dr. John Cush
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197 ANCA assoc Vasculitis pts in RAVE - treated w/ RTX or CTX, thenAZA. 18/22 severe infections occurred within 6 months. Predictors of severe infx included higher baseline CD19+B cells & PJP prophylaxis w/ TMP/SMX (both groups Rx RTX or CYC/AZA) https://t.co/YhNDCdJuof https://t.co/Fg8AOLtYbI
Dr. John Cush
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Advancing Telehealth in Rheumatology
https://t.co/XZTkGQMImc https://t.co/QJjXzjAx5Q
Dr. John Cush
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Rheumatic Disease - IBD Overlap
Nearly one in 10 patients with IBD also have rheumatologic disorders, meaning that specialists have to talk to each other to develop a treatment plan that works for both conditions, a researcher suggested.
https://t.co/s3u9q8Sw9Y https://t.co/RjFyEcm6FA
Dr. John Cush
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AI Passes U.S. Medical Licensing Exam
Two artificial intelligence (AI) programs -- including ChatGPT -- have passed the U.S. Medical Licensing Examination (USMLE), according to two recent papers.
https://t.co/E5GEWrJR00 https://t.co/nd9PrLVn4U
Dr. John Cush
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VEXAS may be more common than expected
A great study of a recently described rheumatologic/hematologic disorder VEXAS syndrome recently appeared in JAMA, describing the frequency and presentations of UBA1 variant.
https://t.co/HeYdjTKiqV https://t.co/T7lKHaQU3Z
Dr. John Cush
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What separates a Great Rheum from an Elite Rheumatologist?
MJR
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Skin manifestations in MDA5 phenotype #inflammatorymyopathy
✅Punched out ulcers on arm, forearm, extensor aspect of elbow
✅Extensive ulcers in PIP and DIP creases
✅Vasculitic rash over fingers with digital ischemia and erythematous palmar papules
👉https://t.co/hUc6Lakww0 https://t.co/smJ1BrSWGc
Dr. John Cush
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Variable Pregnancy Outcomes with Belimumab in SLE
An analysis looked at outcomes in pregnant SLE exposed to belimumab reported there are few pregnancies and confounding disease and comorbidity factors to provide clear guidance for such patients.
https://t.co/nBzoyL4cHW https://t.co/UYIAsfRtB8
Dr. John Cush
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"Dry Synovitis" exist in juvenile arthritis pts? Study of 12 DS pts, says its different from Poly #JIA; onset 6.1 yrs, w/ polyarthritis, no palpable swelling, progressive LOM/contractures, neg ESR/CRP/RF/CCP, +MRI synovitis w/ osteochondral involvement.https://t.co/okGPCsIPNs https://t.co/XlFhgTtq5b
Dr. John Cush
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Why not end your patient visit with a recitation pledging your service and commitment:
"Your coming to see me to day is very important, to the both of us. I pledge to be of service to you. Together WE can certainly improve your health" https://t.co/HrzbipL1ZG https://t.co/amDCk309wi
Dr. John Cush
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JAK-pot Study: To Cycle or Switch after JAK inhibitor Failure?
Data from 17 international registries suggest that for RA patients failing their first JAKi, it did not matter if they were cycled to another JAKi or switched to a bDMARD.
https://t.co/WunRxeF5Wm https://t.co/cOIjglnPNU
Dr. John Cush
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Subanalysis of Scleroderma Lung Study II (MMP vs CTX in SSc-ILD) showed pt reported GI reflux (~moderate) was independently associated with the change ILD and fibrosis over two years (but not so for esophageal dilation) https://t.co/5Gz2vfOock https://t.co/N2FsvNe24M
Dr. John Cush
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AS, but not PsA, has Increased Mortality Risk
A recent meta-analysis showed a significantly increased risk of overall mortality in ankylosing spondylitis (AS) but not psoriatic arthritis (PsA), largely associated with cardiovascular-specific mortality.
https://t.co/bi3q7LW4S6 https://t.co/DUc9sB4MI0
Dr. John Cush
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Simon Says “Don’t Do This”
Dr. Jack Cush reviews this week’s journal articles, focuses on studies that should not have been done and responds to viewer questions in Ask Cush Anything.
https://t.co/ZisyCRxV6L https://t.co/inYDkKKJO3
Dr. John Cush
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CDC: Nursing home residents not up to date w/COVID-19 vaccines have 30%–50% higher risk for COVID infx vs those up to date. Betw 2022-23 Those vax had COVID rate of 7.2-15.6/1000pts vs 9.5-18.8/1000 pt in those unvaccinated. https://t.co/Eem2H5AMoN https://t.co/o2ZyPVswZp
Dr. John Cush
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VEXAS may be more common than expected
A great study of a recently described rheumatologic/hematologic disorder VEXAS syndrome recently appeared in JAMA, describing the frequency and presentations of UBA1 variant.
https://t.co/OFaeH62eHy https://t.co/7znps74Llv
Dr. John Cush
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Blood Test Identifies Osteoarthritis Progression
A new blood test that can identify progression of osteoarthritis in the knee is more accurate than current methods, providing an important tool to advance research and speed discovery of new therapies.
https://t.co/hOAjxJhnJG https://t.co/Ehr5imPNQ4
