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Drug Naming Games (2.7.2025)
Dr. Jack Cush reviews the news, regulatory and journal reports from the past week on RheumNow.com.
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Granzyme - a major driver of inflammatory & autoimmune diseases
EurekAlert!
Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that patrols our body, ever vigilant for signs of infection or injury.
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Can AI pass the rheumatology boards? Yes! 🤯
Stay tuned for more interesting rheumatology pearls at RheumNow Live 2025!
#RNL2025 @RheumNow https://t.co/bNurQlH5OU
Adela Castro AdelaCastro222 ( View Tweet)
🏈Kick-off of @RheumNow w Jeff Curtis #RNL2025 🏈
AI in RA?
Can help with Rheum Boards Questions, though AI is not confident in answers
May not be better than paper charts for triage
Other roles: pt chatbot, AI scribe, research populations, generate DDx, consume guidelines https://t.co/X43DCmt0Ov
Links:
Eric Dein ericdeinmd ( View Tweet)
Who’s liable for an incorrect #AI diagnosis or medical advice? @rheumnow #RNL2025 @RADoctor
TheDaoIndex KDAO2011 ( View Tweet)
Where is the best future of AI in rheumatology in 2 years?
@RheumNow #RNL2025
Jeff Curtis, AI in Rheumatology
Eric Dein ericdeinmd ( View Tweet)
Different types of IFNs have different actions and signaling pathways. Dr. Crow #RNL2025 @rheumnow https://t.co/1lJFwlhO92
TheDaoIndex KDAO2011 ( View Tweet)
Some pearls from RA POD at #RNL2025
-What do rheumatologists want from AI: Right drug for right patient, improving documenting in less time and possibly include multimorbidity management?
-Utilize AI as enhancer not replacement of the physician. AI must be trained well in a… https://t.co/9YNmeVx4t6
Adela Castro AdelaCastro222 ( View Tweet)
ACR Commends Legislation Addressing Harmful Medicare Payment Cuts to Physicians
The ACR applauded the bipartisan introduction of the Medicare Patient Access and Practice Stabilization Act of 2025, legislation to fully offset the harmful 2.8% cut in the Medicare Physician Fee… https://t.co/UqBbAyHLm0 https://t.co/3DJN7ojMHl
Dr. John Cush RheumNow ( View Tweet)
How can AI be useful for RA pts and rheumatologists?
-AI models have the potential for improving diagnosis, management and outcomes in RA pts.
-Can also improve efficiency and clinic workflow.
-Not so perfect as it sounds (hallucinations, limited accuracy)
#RNL2025 @RheumNow https://t.co/44LUHQ1KPf
Adela Castro AdelaCastro222 ( View Tweet)
AI models require good Positive Predictive Value (PPV)
But: PPV decreases as prevalence decreases
- In choosing a successful biologic:
Harder to predict more challenging patients (multiple failures, co-morbidities, etc) - ACR50 non-response is higher
J Curtis
@RheumNow #RNL2025 https://t.co/SdJ0FHVuSC
Eric Dein ericdeinmd ( View Tweet)
Rheumatic diseases become more common with aging, dramatically so. @UnaMakris @RheumNow #RNL2025 https://t.co/EXKHP9ufUj
Richard Conway RichardPAConway ( View Tweet)
#RNL2025 is underway! https://t.co/VDEvK70Qg5
Dr. John Cush RheumNow ( View Tweet)
Such an important topic from @UnaMakris . The intersection of aging with our rheumatic disease processes is a crucial area. @RheumNow @RNL2025 https://t.co/n0Kx559g9e
Richard Conway RichardPAConway ( View Tweet)
J Curtis #RNL2025 @RheumNow
AI Will Not Replace You
- AI cannot replace human interaction, examination, procedures, interpreting guidelines for an individual, providing empathy, and facilitate good patient education
Will become a tool... but not a replacement to a good clinician https://t.co/qPcNOjWepi
Eric Dein ericdeinmd ( View Tweet)
AI is here to stay! It should be our ally in optimizing patient care and efficiency at work.
Here are the 10 commandments of AI from an amazing lecture from @RADoctor at #RNL2025 #AI #Rheumatology @RheumNow https://t.co/6BajZxGkwe
Links:
Adela Castro AdelaCastro222 ( View Tweet)
QD Clinic - New Palmoplantar Psoriasis and PsA
New Onset Palmoplantar PsO and PsA - what are the options?
Features Dr. Jack Cush.
QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025
Register at https://t.co/2dcFVgu8z6… https://t.co/3ubBL6HVGF https://t.co/Zdd6Dih5eZ
Links:
Dr. John Cush RheumNow ( View Tweet)
BSR Guideline on Management of Sjögren disease
The British Society for Rheumatology has published its guideline for the management of adult and juvenile onset Sjogren's disease.
https://t.co/UJOvb937lk https://t.co/P77h91nPuN
Dr. John Cush RheumNow ( View Tweet)
QD Clinic - dsDNA without Lupus
Insufficient Sxs to Dx SLE, but persistent dsDNA positivity - what to do?
Features Dr. Jack Cush.
QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025
Register at https://t.co/2dcFVgu8z6… https://t.co/ov8THqrPyC https://t.co/jmtqxcWzJ0
Links:
Dr. John Cush RheumNow ( View Tweet)
QD Clinic - New Palmoplantar Psoriasis and PsA
New Onset Palmoplantar PsO and PsA - what are the options?
Features Dr. Jack Cush.
QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025
Register at https://t.co/2dcFVgu8z6… https://t.co/HZZuDvga58 https://t.co/wWKhnIECwB
Links:
Dr. John Cush RheumNow ( View Tweet)
