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okay, so let's look at the #ACR21 plenary as we go so a reminder - FDA-mandated phase 3b/4 safety endpoint study specifically looking at patients >50yo with at least one other CV risk factor today we're looking at MACE: that's CV death (excl PE), MI, stroke ABST0958 @RheumNow https://t.co/9U8Sahb9Q7
David Liew drdavidliew ( View Tweet)
Vitamin D ⬇️incident autoimmune diseases & so do fatty acids but latter is not stat signif. 25k older adults with factorial design, no interaction. ? Buy vit D stock @RheumNow #ACR21 #ACRBest VITAL trial abst#0957 https://t.co/Qk3VwNOZie
Janet Pope Janetbirdope ( View Tweet)
Can vit D, omega-3 fatty acids prevent autoimmune dx development, even in non-deficient people? (some plausibility, no other meds can) vit D *might* have an effect, esp post-2y cautious interest seems okay! extension worth looking at VITAL trial add-on #ACR21 ABST0957 @RheumNow https://t.co/H5aF8Vl79u
David Liew drdavidliew ( View Tweet)
Can vit D and omega3 prevent autoimmune dz? 25,871 adult pts randomized:vit D 2000 IU daily, omega 3 (1 g/d), combo, PCB and followed 5 yrs Vit D & combo showed statistical sig over time, omega3 showed a favorable trend Abst#0957 #Plenary #ACRbest @rheumnow https://t.co/moMCm9IJmO
TheDaoIndex KDAO2011 ( View Tweet)
Take your supplements 🐠 fish oil and Vit D! VITAL RCT presented by @karen_kc123 shows Vit D +/-n-3 fatty acid ⬇️ incidence of AID compared to PBO. Promising although AID were self reported! @RheumNow #ACR21 #Abst0957 https://t.co/xdEdKuwXci #ACRBest https://t.co/zWrr9oC7F5

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Aurelie Najm AurelieRheumo ( View Tweet)
Interesting study with Dr. Julia Manasson on gut and skin microbiome in monozygotic twins discordant for psoriatic disease. (red = Psoriatic). Gut ruminococcus bromii virtually absent in psoriatic pts. Eager to see further studies! #ACR21 Abst#0944 @RheumNow https://t.co/zrZPBAjh5p
Pedro Castillo _Castillo_Pedro ( View Tweet)
Clinical Pearl at @ACR21 Is patchy tongue erythema + angular chelitis representative of Sjogren's or oral candidiasis? Beware: Oral candiasis is a mimic of Sjogren's tongue. Differentiate by asking if burning of tongue. If so, not Sjogren's -- start PO antifungal! @RheumNow https://t.co/FbdiX8PFKV
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
I honestly find Vit D literature confusing! VITAL RCT omega3 and vit D in preventing autoimmune diseases. They seems to work?🧐The confidence intervals just shy of 1.00...I am still skeptical..but keeping vit D normal doesnt hurt I guess....#ACR21 @rheumnow abst#0957 https://t.co/QFcz2zK4Ic
Bella Mehta bella_mehta ( View Tweet)
Physician global score was the strongest predictor of future flares in AS patients with TNFi dose tapering. 29 (27%) flared at 2/3 of standard dose, 21 (20%) at 1/2 dose, 29 (27%) at 1/3 dose and 27 (25%) after discontinuation @RheumNow #ACR21 Abst#0929 https://t.co/pIzLgexe3k https://t.co/UM9cGLiYl7

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Dr. Antoni Chan synovialjoints ( View Tweet)
Abst#0946 shows a distinct lipid profile in RA vs PsA synovium + synovial fluid. Sphingomyelins & phosphatidyl-cholines/ethanolamines had the greatest separation power to classify RA + PsA samples. These lipid markers may have clinical utility if validated. #ACR21 @Rheumnow https://t.co/ktKRypTtlE
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
SKIPPAIN results: Spinal pain response after 8 weeks of SEC showed notable differences between HLA-B27 subgroups. Can subtype pre-determine tx efficacy/response? Abs 0917 #ACR21 #RheumNow @RheumNow https://t.co/FKpCqXpobM https://t.co/WbjjyTIaiG

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Dr. Rachel Tate uptoTate ( View Tweet)
MCP, wrist, elbow, shoulder and ankle: Not common sites for #osteoarthritis so consider a metabolic disease like CPPD🧐 @RheumNow #ACR21 #RheumTwitter #MedTwitter https://t.co/utId4ljsZK
sheila RHEUMarampa ( View Tweet)
IV Golimumab efficacy and Early (ED) vs Late (LD) AS ⭐️ED better response than LD with PRO ⭐️Treatment-emergent adverse events/ serious adverse 🔼 LD as compared to ED Abst #0912 #ACR21 @RheumNow https://t.co/5EaWAvfQ57
swethaann23 swethaann23 ( View Tweet)
Outcomes of COVID-19 in Patients with Rheumatoid Arthritis. Dr. Akhil Sood ( @AkhilSoodMD) shares the studies presented #ACR21. https://t.co/yrs8N8XSiS https://t.co/EKHuTS5aDr

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Dr. John Cush RheumNow ( View Tweet)
My "followers" just don't get me. #ACR21 #RheumPix https://t.co/E6gy6RVMBy
Dr. John Cush RheumNow ( View Tweet)
Nationwide study - low income - greater length of stay than highest income. Lowest income many be supported but those who do not have those resources may have an increased length of stay in children hospitalized with pediatric #lupus @dsoulsMD @rheumnow #ACR21 abst#0768 https://t.co/j7VDpVW7ND
Bella Mehta bella_mehta ( View Tweet)
GO-ALIVE study by Prof ADeodhar & grp 🔘IV GOL was shown to be effective across all efficacy outcomes in AS pts w/ early & late dse 🔘⬆proportions of pts w/ early dse achieved BASDAI50 and ASDAS inactive dse Early dx and tx 👉better outcomes @RheumNow #ACR21 #ACRBest abs0912 https://t.co/jwvEn5LdDB
sheila RHEUMarampa ( View Tweet)
CV events go down when #hydroxychloroqine dose goes up in SLE BUT only in non smokers. Maybe due to smoking attention of HCQ levels &/or smoking as a bigger risk for CV over rides HCQ dose? ⬇️cardiac events by 28% in non-smokers abst0871 #ACR21 @RheumNow #RheumPix https://t.co/XxgK7iRXWi
Janet Pope Janetbirdope ( View Tweet)
Physician global score only predictor of axSpA flares when tapering TNFi ⭐️Changes in imaging did not predict flare Abs#929 #ACR21 @RheumNow https://t.co/vVn6ARKJu0 https://t.co/FlVtlLmTfl

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Robert B Chao, MD doctorRBC ( View Tweet)
Unconscious bias affects all of us. If you don’t see color then you’re not color blind but lying, paraphrasing Dr Rose-Smith #ACR21 7S117. Free downloadable slides from talk including exercises to ⬇️implicit bias @RheumNow Say to pt ex help me make decision that is right for you https://t.co/cdTFlkuBja
Janet Pope Janetbirdope ( View Tweet)
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