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CV events go down when #hydroxychloroqine dose goes up in SLE BUT only in non smokers. Maybe due to smoking attention of HCQ levels &/or smoking as a bigger risk for CV over rides HCQ dose? ⬇️cardiac events by 28% in non-smokers abst0871 #ACR21 @RheumNow #RheumPix https://t.co/XxgK7iRXWi
Janet Pope Janetbirdope ( View Tweet)
Physician global score only predictor of axSpA flares when tapering TNFi
⭐️Changes in imaging did not predict flare
Abs#929
#ACR21 @RheumNow
https://t.co/vVn6ARKJu0 https://t.co/FlVtlLmTfl
Robert B Chao, MD doctorRBC ( View Tweet)
Unconscious bias affects all of us. If you don’t see color then you’re not color blind but lying, paraphrasing Dr Rose-Smith #ACR21 7S117. Free downloadable slides from talk including exercises to ⬇️implicit bias @RheumNow Say to pt ex help me make decision that is right for you https://t.co/cdTFlkuBja
Janet Pope Janetbirdope ( View Tweet)
Don't forget, sometimes, taking off the mask is worth it!
@RheumNow #ACR21 #clinicalpearls https://t.co/WAdSZEm4pe
sheila RHEUMarampa ( View Tweet)
French real-world AxSpA cohort analysis showed drug retention of SEC & TNFi were similar. In subgroups analyses, age, BASDAI at dx & BMI were similar. Abs 0911 #ACR21 #RheumNow @RheumNow https://t.co/ewtmpxKTNu https://t.co/Yh0nX3x83Z
Dr. Rachel Tate uptoTate ( View Tweet)
#ACR21 Rheum Secrets and Pearl
Lupus pernio on the nasal ala.
⭐️Lupus in the name, but this is #sarcoid and not same as perniosis (chillblains)
@Rheumnow https://t.co/r49yjkjsje
Eric Dein ericdeinmd ( View Tweet)
Pearl: Erythema nodosum isn't typically located on the posterior calf and does not ulcerate; if it does👉consider #vasculitis
@RheumNow #ACR21 #RheumTwitter https://t.co/hlsaQLj7cN
sheila RHEUMarampa ( View Tweet)
Plenary at #ACR21 Renal outcome Risk of minority patients with pediatric #lupus @rheumnow abst#0956
inpatient hospitalizations. https://t.co/HK8w246Dsn
Bella Mehta bella_mehta ( View Tweet)
#ACR21 Rheum Secrets and Pearls
High CRP - not a typical marker of SLE flare. Look for infection!
@Rheumnow https://t.co/g1Z6OHvANv
Eric Dein ericdeinmd ( View Tweet)
Do you use RAPID3 in PsA?
Abst#0633 at #ACR21 shows a strong agreement between RAPID3 remission score w/ DAPSA + cDAPSA, esp when redefining RAPID3 categories.
Is this practice △ing? With more studies to validate, yes, since RAPID3 is simpler!
@RheumNow https://t.co/2q0FLeBSkC https://t.co/M3WDTGzEOT
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Always one of my favourite sessions at #ACR21- #Rheumatology #SecretsAndPearls
Dr Kolfenbach reminds us of the importance of discussing #lifestyle, #smoking and #diet with our patients in clinic.
@RheumNow #InflammatoryArthritis #RheumatoidArthritis #PsA https://t.co/2gadRBLCTb
Mrinalini Dey DrMiniDey ( View Tweet)
VITAL RCT of Omega-3 and Vit D in preventing autoimmune diseases in 25,871 individuals. They both work! Reducing incident autoimmune disease by 25-30%. This is game-changing! Abstr#0957 #ACR21 @RheumNow #ACRBest https://t.co/BaeZDTTnQf
Richard Conway RichardPAConway ( View Tweet)
Elevated CRP? Dr. Kolfenbach reminds us that it is not typical of #SLE flares, rule out INFECTION!
@RheumNow #ACR21 #RheumTwitter #MedTwitter https://t.co/FnkPdZ8gSl
sheila RHEUMarampa ( View Tweet)
"We need to do more than improving quality of care to close the gap in racial disparities." - Dr. J Chang
Trends of adverse renal outcomes⬇️w/time in children hosp w/SLE. Improvements seen across racial/ethnic group, but black-white disparity persists abst#0956 #ACR21 @rheumnow https://t.co/HcOwQiKCb2
TheDaoIndex KDAO2011 ( View Tweet)
#ACR21 Rheum Secrets and Pearls
Is it Allopurinol or adherence concern?
Oxypurinol can be helpful in measuring adherence!
Kolfenbach: "I despise the term non-compliant patient." Address the many reasons why adherence may be low! Health literacy is key.
@Rheumnow https://t.co/CPJ8kvqcCm
Eric Dein ericdeinmd ( View Tweet)
Although baseline dz was similar in axSpA males/females, study found male pts had more improvements in ASDAS-CRP, CRP, and PGA than females in 6 years of follow-up. Abs 0620 #ACR21 #RheumNow @RheumNow https://t.co/Qr657YeniA https://t.co/35t4oIUSmS
Dr. Rachel Tate uptoTate ( View Tweet)
An ongoing axSpA cohort in Netherlands study assessed the rate of progression of nr-axSpA to AS patients over a 6 y period
Every 2 y approximately 10% of patients progressed from nr-axSpA to AS
Abst # 0907 #ACR21 @RheumNow https://t.co/gGhhssLS5N
swethaann23 swethaann23 ( View Tweet)
#ACR21 Abst#0836. TCZ switch from IV▶️SC in RA
⭐️11/37 ineffective on SC (30%)
⭐️TCZ IV >8mg/kg, no MTX, h/o ABA failure ass w/ risk of flare on SQ switch
🔥Very relevant w shortages, want more data re: confounders (adherence, disease control)
https://t.co/E9pD4SrXqz @Rheumnow
Links:
Eric Dein ericdeinmd ( View Tweet)
Getting closer to personalised medicine in AS, ECM-mediated biomarkers may help predict response to Adalimumab in AS. The biomarkers C1M, C6M and
PRO-C4 were lower in responders to adalimumab treatment after 24 weeks @RheumNow #ACR21 Abst#0915 https://t.co/K2YxPvUAwu https://t.co/w9kcBSFeG9
Dr. Antoni Chan synovialjoints ( View Tweet)
Interesting study. 79 nr-axSpA pts observed for 6 years. Every 2 yrs approximately 10% of pts progressed from nr-axSpA to AS! Next step: evaluate dz characteristics and determine potential at risk pts. Abs 0907 #ACR21 #RheumNow @RheumNow https://t.co/aRjXWjkVKg https://t.co/BiHFgDR8Kv
Dr. Rachel Tate uptoTate ( View Tweet)