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🚨 DESIRES study. DB RCT in systemic sclerosis. Significant benefit of Rituximab in Rodnan skin score and FVC! Abstr#496 #ACR21 @RheumNow #ACRBest https://t.co/Ta6Cq8XZie
Richard Conway RichardPAConway ( View Tweet)
Lots of excellent abstracts at #ACR21 on assessment & impact of #comorbidities & #multimorbidity in RA, some discussed in this article @RheumNow:
https://t.co/WXgv1GmHD6
Featured abstracts:
#0798 https://t.co/02BRqYp9Yk
#1450 https://t.co/iG2s2Cy8Q0
#1924 https://t.co/qHws6ALENH
Links:
- Towards better assessment and management of multimorbidity | RheumNow
- The Impact of Comorbidities on the Simple Disease Activity Index (SDAI) and Its…
- Unsupervised Machine Learning Methods to Cluster Comorbidities in a Population-…
- Patient Clustering Based on Multimorbidity Patterns Predicts Healthcare Utiliza…
Mrinalini Dey DrMiniDey ( View Tweet)
Cool talk by P Grayson - how to design ANCA vasculitis RCTs with biomarkers, umbrella/basket RCT designs to treat pts MORE likely to respond. Also for an individual, following ANCA is not that helpful for altering Rx Take a look at this session GS401 #ACR21 #ACRBest @RheumNow https://t.co/nrapO9i4gw
Janet Pope Janetbirdope ( View Tweet)
Abst 0478
Binvignat et al performed hierarchical clustering analysis based on cardinal symptoms in hand OA
- Identified 5 Phenotypes
- Symptoms correlated with metabolic syndrome, joint destruction & physical and psychological burden
#ACR21 @RheumNow https://t.co/O9hweqNIS8
Akhil Sood MD AkhilSoodMD ( View Tweet)
Bimekizumab (IL-17A and IL-17Fi) 3 year safety and efficacy in PsA Phase IIb trial
⭐️no new safety signals
⭐️candida infections were all mild/moderate
⭐️efficacy consistent and maintained
Abs#491
#ACR21
@RheumNow
https://t.co/BK6xPMqAEM https://t.co/meoPd7k0Xp
Robert B Chao, MD doctorRBC ( View Tweet)
Dr. Atul Deodhar with an excellent presentation on treatment in axSpA and axPsA. Note ustekinumab and risankizumab did not show improvement in axSpA. However, these studies did not include axPsA.
@ACR21 6S403 @RheumNow https://t.co/F73lvpF2at
Pedro Castillo _Castillo_Pedro ( View Tweet)
More from Dr. Atul Deodhar on treatment of axSpA and axPsA. Guselkumab studies DISCOVER 1 & 2 looked at PsA with sacroiliitis and demonstrated improved measures of axial activity, but we need more studies and to include MR imaging.
#ACR21 6S403 session @RheumNow https://t.co/8jM5Fj8MuD
Pedro Castillo _Castillo_Pedro ( View Tweet)
Abst 0370 #ACR21 @rheum survey of PCPs reveals lack of awareness about inflammatory back pain: 58%never/rarely assess for IBP; 40% not comfortable with making the dx of IBP. 83%never/rarely ordered HLAB27, 65% never/ rarely ordered CRP, 72% rarely/never ordered X-ray SI joint
Olga Petryna DrPetryna ( View Tweet)
New therapies this year in rheumatology #ACR21 year in review Avacopan in AAV and Voclosporin in Lupus nephritis @RheumNow @karen_kc123 https://t.co/8Z28STMJ6X
Bella Mehta bella_mehta ( View Tweet)
Using machine learning to predict knee cartilage worsening over 2 years sing gait and physical activity using the MOST study #abst0210 #ACR21 @RheumNow https://t.co/0MAjLhpL7t
Bella Mehta bella_mehta ( View Tweet)
Overlap between RA and SLE: is the famous rhupus more frequent than it seems? In the Boston OM1 SLE Registry w/ 44,186 SLE: 4.7% also reported as having RA. This is higher than the usual reported prevalence. #ACR21 #Abst0354 @RheumNow https://t.co/FYfvSdCkkF https://t.co/ISuae2hCI3
Aurelie Najm AurelieRheumo ( View Tweet)
Abst 0281 England & colleagues used unsupervised ML to determine whether peripheral biomarkers can accurately identify RA-ILD in large RA cohort
- Identified 8 unique groups based on biomarkers
- RF, anti-CCP, and -MAA biomarkers most closely associated w/ ILD https://t.co/831tP4JSh0
Akhil Sood MD AkhilSoodMD ( View Tweet)
Rheumatologists and Health Professionals: Join us tonight for RheumNow's #ACR21 Daily Recap at 7pm Eastern time . Register via the Zoom link below.
https://t.co/IQSL0mpEjR
Or visit our YouTube channel-RheumNow.
https://t.co/Nm74eS5T5H https://t.co/syaHSDJWOv
Dr. John Cush RheumNow ( View Tweet)
PsA patients should be screened for spinal involvement, which may not be picked up on initially if we aren't looking for it. Presented by Dr. @annamolto
#ACR21 6S403 @RheumNow https://t.co/frB2zbHtXG
Pedro Castillo _Castillo_Pedro ( View Tweet)
Early CV changes in #Rheumatoidarthritis abst#0271 showed more subclinical atherosclerosis vs controls in ERA, Abs ⬆️MACE &CV death in RA pts, abst#0269 ex RF, ACPA, MAA. Lipids ⬆️differently in RA given #tocilizumab vs TNFi BUT unrelated to CV events abst#0269 #ACR21 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
#ACR21 The Great Debate: Belimumab vs Voclosporin as Add-On Therapy in #LupusNephritis | Dr. Petri & Dr. Rovin
Audience Vote 🗳: What would you add to mycophenolate first?
Belimumab 71%, Voclosporin 29%
#ACRAmbassador @ACRheum
Summary of Pros & Cons of Each⬇️ https://t.co/OtLxs8IYr9
Mithu Maheswaranathan, MD MithuRheum ( View Tweet)
Young et al. Impact of COVID-19 on rheumatology training
302 rheumatology trainees from 33 countries surveyed
➡️52% feel burned out🔼from prior
➡️66% felt supported by their program
➡️72% felt positive about being in Rheumatology
Abst#0485 #ACR21 @RheumNow @kristenyoung
swethaann23 swethaann23 ( View Tweet)
Excellent talk by Dr. Anna Molto. Characteristics of spondyloarthritis, noting some patients with PsA have radiographic and non-radiographic axial SpA.
#ACR21 6S403 @RheumNow https://t.co/ycftOMrWO9
Pedro Castillo _Castillo_Pedro ( View Tweet)
Do you use ANCA to change Rx in prevalent GPA pts? GS401 #ACR21 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
OMG, the fear of missing something due to the discordant daylight savings shift is real! https://t.co/1mi2QnrHDl
Richard Conway RichardPAConway ( View Tweet)