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How Do You Measure Success When It Comes to SLE?

d Kathryn H. Dao, M.D.

EULAR 2021 opened with a grand debate to answer this essential question:  should clinicians treat to remission or to Lupus Low Disease Activity State (LLDAS)?  

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Q-DAPSA for Measuring Disease Activity in PsA

d Rachel Tate, DO

Given its multiple domains, there remains much discussion over the best disease activity scoring method in PsA. The proverbial "holy grail" would be a measure that is quick, intuitive, domain comprehensive and validated.

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RA ILD: Stepping out of the shadows

d Richard Conway, MBBChBAO, PhD

Despite being relatively common and frequently severe, RA-ILD has been a neglected area of research and indeed of clinical management in RA. In recent years we finally seem to have started making some progress in this area and this momentum has continued with a several interesting abstracts at EULAR 2021. Here are four selected for review.

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EULAR 2021 Best Abstracts - Day 1

d Jack Cush, MD

RheumNow faculty reporters scoured the Posters and Presentations from virtual EULAR 2021.  Several of these are novel enough to be worthy of your consideration.  Below is the list of the six most often retweeted abstracts from Day 1.

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Lessons learned in SLE

d Janet Pope, MD, MPH, FRCPC

An analysis of SLE samples from SLE 1760 patients with active disease from RCTs illustrated several known and some new targets for SLE treatment (POS0351).

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DPGN, lupus, nephritis, GN, glomerulonephritis, biopsy, kidney

Combination vs. Sequential Therapy for the Treatment of Lupus Nephritis

d Kathryn H. Dao, M.D.

Combination disease modifying antirheumatic drug (DMARD) therapy may not be only for rheumatoid arthritis; combining disease modifying agents may be the path to better renal response. 

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malar lupus

Promising options to treat mucocutaneous disease in SLE

d Md Yuzaiful Md Yusof, MRCP(UK), PhD

Cutaneous lupus erythematosus (CLE) consists of a wide range of dermatologic manifestations seen in people with or without systemic lupus erythematosus (SLE). CLE can be categorised into LE-specific lesions, i.e.

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Can the Focus Score predict Lymphoma in Sjogren’s syndrome?

d Eric Dein, MD

Patients with Sjogren’s syndrome are nearly 19 times more likely to develop lymphoma, so identifying factors that impact this risk development is a major goal in caring for this disorder.

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WATCH: Have you heard about the advances in RA discussed at #EULAR2021? Our panel of doctors break down everything you need to know. https://t.co/C4FAQRFOhG https://t.co/tsQDW7LOFZ

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Dr. John Cush RheumNow ( View Tweet)
Promising options to treat mucocutaneous disease in SLE #EULAR2021 https://t.co/JoChBNRfqu https://t.co/6jjhuEOQgO

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Dr. John Cush RheumNow ( View Tweet)
Video: Combination DMARD for Lupus Nephritis: Dr. Kathryn Dao ( @KDAO2011 ) #EULAR2021 https://t.co/RGVZ6jukYy https://t.co/PTjSOfM7YQ

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Dr. John Cush RheumNow ( View Tweet)
Video: Treatment Options for PsA Patients: Dr. Paul Studenic Dr. Paul Studenic reviews highlights from three PsA abstracts - abstract op0227, abstract op0229, and abstract op0233 - presented at the virtual #EULAR2021 meeting. https://t.co/QlquUQFQOJ https://t.co/p5wBTboIpE

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Dr. John Cush RheumNow ( View Tweet)
Can the Focus Score predict Lymphoma in Sjogren’s syndrome? by Dr. Eric Dein ( @ejdein1 ) https://t.co/B5HN6ju3ru https://t.co/3MuXH66YqJ

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Dr. John Cush RheumNow ( View Tweet)
Video: Did I Forget Something? Dr. Jonathan Kay ( @RheumKay ) Dr. Jonathan Kay examines abstracts OP0216 and OP0215 that were presented at the virtual #EULAR2021 meeting. https://t.co/Vaa570r7WE https://t.co/mNQJyOiNep

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Dr. John Cush RheumNow ( View Tweet)
Video: Impact of RA on Male Fertility: New Data: Dr. Aurelie Najm Dr. Aurelie Najm reviews abstracts OP0211 and OP0212 presented at the virtual #EULAR2021 meeting. https://t.co/AHwhyLiwD0 https://t.co/sm7cSBPIBV

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Dr. John Cush RheumNow ( View Tweet)
Psoriatic arthritis mortality & morbidities by Dr. Paul Studenic #EULAR2021 PsA is a chronic condition with manifold clinical presentations. Health issues may be far beyond the classical associated conditions like uveitis, enthesitis etc. https://t.co/zHfeaiiG93 https://t.co/AoHenH6YkK

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Dr. John Cush RheumNow ( View Tweet)
Video: The PsA SpA Paradox of Choice Dr. Rachel Tate ( @uptoTate) reviews Dr. Laura Coates' presentation Personalized Treatment Strategies in Psoriatic Arthritis, given at the virtual #EULAR2021 meeting. https://t.co/Yg12SHR1MF https://t.co/UiCYDU5XGc

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Dr. John Cush RheumNow ( View Tweet)
New GRAPPA 2021 PsO and PsA Treatment Recommendations by Dr. Rachel Tate ( @uptotate) The evidence-based recommendations from the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis were presented at #EULAR2021. Read more... https://t.co/AnHQGA8aKs https://t.co/4c18j4h54T

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Dr. John Cush RheumNow ( View Tweet)
Video: Personalization of PsA Treatment: Dr. Robert Chao ( @doctorRBC) Dr. Robert Chao reviews a talk given by Dr. Laura Coates entitled, "Towards personalized treatment strategies for psoriatic arthritis", presented #EULAR2021. https://t.co/LeocvUyZ7N https://t.co/g6ApPL0Pui

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Dr. John Cush RheumNow ( View Tweet)
Do B-cell targeted therapies still have a place for the treatment of Sjogren’s? #EULAR2021 https://t.co/96sv3beMvG https://t.co/EWKCA1KGsC

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Dr. John Cush RheumNow ( View Tweet)
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