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⭐️JUNIPERA: RCT of SEC in active ERA & JPsA (2-18yo, most on MTX) -Tx . (TP)1: SEC 75/100 mg till wk 12 -TP2: cont SEC or switch to PBO till wk 104 ⭐️SEC efficacious on JIA ACR30/70 ⭐️74% w/ resolution of enthes ⭐️Median T2flare in PBO in TP2 = 453d LB0004 #EULAR2021 @Rheumnow https://t.co/JsG2pXz9r6
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
What to tell pts about diet? *⃣Nutrition plays a role in inflammation in RMD & co-morbidities. What you eat matters! *⃣ LImit salt, replace w/ herbs *⃣ Consume low glycemic index foods. Soda ⬆️risk of RA in women *⃣⬆️omega-3 ⬇️omega-6 (dairy, eggs) #EULAR2021 @Rheumnow

Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)

#EULAR2021 POS0236 Comparison of work productivity b/w CBP w & w/o AxSpA - 2 years from SPACE cohort ⭐️AxSpA showed significant ⬇️ in work productivity loss (WPL) compared to CBP wo AxSpA Can use to counsel AxSpA patients that we have effective Rx for return to work @RheumNow

Eric Dein ejdein1 ( View Tweet)

#EULAR2021 POS0237: Gut dysbiosis linked to worse disease status in axSpA. ⭐️Dysbiosis in 33% of AxSpA vs 17% of controls wo rheumatic disease ⭐️Gut dysbiosis associated with worsening disease activity @RheumNow https://t.co/rRl4Zbs7xc
Eric Dein ejdein1 ( View Tweet)
BUT.....the SEC results were significant if you only looked at those with moderate to severe rotator cuff tendinopathy? Curious study, I think worthy of a well designed prospective trial. https://t.co/kqGink3sjU

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Dr. John Cush RheumNow ( View Tweet)

Baseline Vitamin D 😎☀️correlated with biologic response in RA pts. ⭐️EULAR good response: 19.6% Vit D >20 vs 4.2%⬇️Vit D ⭐️Remission: 14.4% ⬆️Vit D vs 3.2% ⬇️Vit D Abs#POS0100 #EULAR2021 @RheumNow

Robert B Chao, MD doctorRBC ( View Tweet)

Time to go raspberry picking? Rubus idaeus leaf extract 400mg and 200mg after 12 weeks ⬇️ VAS pain in knee OA compared to placebo ⭐️no effect on WOMAC, SF-36, 20m walking Abs#POS0281 #EULAR2021 @RheumNow https://t.co/QAiag2XjRh
Robert B Chao, MD doctorRBC ( View Tweet)
Fellow rheumatologists, make sure to take care of yourself! Latin America study ⭐️57% rheumatologists experienced burnout ⭐️associated with ⬇️age, ⬆️hours, ⬇️satisfaction, ⬇️happiness, ⬆️suicidal thoughts, income Abs#POS0302 #EULAR2021 @RheumNow

Robert B Chao, MD doctorRBC ( View Tweet)

MSK US before 1st clinic visit? Abs#POS0260 showed ⬇️ in time to diagnosis of inflammatory arthritis from 31 to 12 days and ⬇️clinical visits 2.8 to 2.1 How do you use MSK US in your clinic? #EULAR2021 @RheumNow

Robert B Chao, MD doctorRBC ( View Tweet)

Mavrilimumab (GM-CSFi) phase II trial of COVID-19 PNA and systemic hyperinflammation ⭐️65% risk reduction in ventilation/death ⭐️no sig difference in ventilation requirement ⭐️no serious AE Abs#LB0001 #EULAR2021 @RheumNow

Robert B Chao, MD doctorRBC ( View Tweet)

Excellent talk on SLE, APS abs pregancy ⭐️pregnancy counseling is important ⭐️aspirin 81mg in all pregnant SLE pts ⭐️do not discontinue HCQ ⭐️stable LN - can switch MMF to AZA Abs#6888 #EULAR2021 @RheumNow

Robert B Chao, MD doctorRBC ( View Tweet)

Close call between LLDAS and DORIS Remission as a treat-to-target in #SLE. Thank you for participating in the polls #EULAR2021 @RheumNow https://t.co/r3OnSrmQkH

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Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)

Results are out. The majority would use #anifrolumab to treat refractory skin and joints disease #SLE. Thank you for participating in the polls #EULAR2021 @RheumNow https://t.co/wguBCkhZ7B

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Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)

No clear winner here. The majority would use #IL23 inhibitors as either 2nd or 3rd line bDMARDs and for #psoriaticarthritis with severe #psoriasis. Thank you for participating in the polls #EULAR2021 @RheumNow https://t.co/b8wzaRVTqw

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Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)

This is by far the biggest rheum dx COVID vaccinated cohort described I'm aware of 👏 Looking forward to full paper, & we will need data with more pts, more details, cellular response etc. Nevertheless, invaluable & reassuring. So glad to see it at #EULAR2021 LB0003 @RheumNow https://t.co/jsHZjLdCTT
David Liew drdavidliew ( View Tweet)
6. Rheum disease activity was stable with COVID vaccination. (RA, PsA, axSpA, SLE - total n = 597) 7/ LB0003 #EULAR2021 @RheumNow https://t.co/xxkrunjPa0
David Liew drdavidliew ( View Tweet)
Israel was early to COVID vaccinate on mass scale. How well did the vaccine work in their rheum dx pts? rheum pts n=686 (vs controls n = 121) - fewer w immunogencity, but not bad (86% vs 100%) - safety good - dx activity stable more details below ⬇️ LB0003 #EULAR2021 @RheumNow https://t.co/h2WT404mkF
David Liew drdavidliew ( View Tweet)
Rituximab in PMR. Intriguing proof of concept (SB?) RCT (1:1, total n=47 (recent dx 38/relapsing 9)) 17w rapid PNL taper ritux 1g x1 21w: steroid-free remission: 48% v 21% PNL ≤5mg/d: 100% v 54% effect mainly from recent dx pts We do need options! POS0343 #EULAR2021 @RheumNow https://t.co/g6xJekY92O
David Liew drdavidliew ( View Tweet)
Treat-to-target is the robust algorithm that dictates all modern RA treatment. What's the target? Ummmm We use it in everyone, right? (both doctors & pts say 66%) We at least use the principles sometimes, right? (86% of us) [holds up mirror to self] POS0305 #EULAR2021 @RheumNow https://t.co/A9MXHMYbag
David Liew drdavidliew ( View Tweet)
On choosing an agent for MTX-IR RA: "(at the end of talk) My short answer could have been... there's no right or wrong. It's still one of the dilemmas we have in the treatment of RA: choosing the right drug for the right patient" - @DanielAletaha #EULAR2021 @RheumNow https://t.co/C45ey1SrA1
David Liew drdavidliew ( View Tweet)
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