All News
#EULAR2021 POS0230: TNFi changes intestinal microbiota in IBD-SpA
⬇️ Proteobacteria
⬆️Lachnospiraceae, Coprococcus
Does inflammatory changes by TNFi restore intestinal eubiosis and does this affect SpA outcomes?
@Rheumnow
Eric Dein ejdein1 ( View Tweet)
#EULAR2021 OP0291 proposes focus score of 4+ as prognostic factor for lymphoma risk in Sjogrens
Focus score 4+:
⬆️lymphoma risk
⬆️salivary gland swelling
⬆️autoantibodies
⬇️thyroiditis
Authors propose 4yr follow-up biopsy in all pts Focus score 4+.
@RheumNow
Eric Dein ejdein1 ( View Tweet)
#EULAR2021 LB0001. Mavrilimumab (blocks GM-CSF alpha) phase2 trial in non-vented patients w/ #COVID19 :
⭐️⬇️ mortality and ventilation at day 29
⭐️61% reduction in death (HR 0.39)
⭐️No drug related SAEs, no dose-related AEs
@Rheumnow https://t.co/9UOi3xF7Re
Eric Dein ejdein1 ( View Tweet)
#EULAR2021 LB0002 #COVID vax safety in RMD
⭐️78% received Pfizer, 16% Astra Zeneca
⭐️5% of pts flares, 1.2% severe flares
⭐️31% had vax side effects, 0.1% severe AEs
Side effect profile similar to gen population. Good data for uncertain patients!
@RheumNow @rheum_covid https://t.co/PGZcph9Mu6
Eric Dein ejdein1 ( View Tweet)
What’s the biggest reason for vaccine hesitancy in your patients? @RheumNow #EULAR2021
Eric Dein ejdein1 ( View Tweet)
#EULAR LB0003 Pfizer #COVID vax immunogenicity and safety in 686 rheum pts in Israel
⭐️Sero+ for COVID Ab 86% in RMD vs 100% controls
⭐️RTX lowest seropos of 39%, related to time of infusion
⭐️⬇️ with GC, ABA, MMF
⭐️ MTX not seen to significantly ⬇️
@RheumNow @rheum_covid
Eric Dein ejdein1 ( View Tweet)
What's your main take-away from COVID vax immunogenicity data at #EULAR2021? LB0003: I'm re-assured that early data has not shown MTX has not shown major ⬇️ in immunogenicity, also seen at @HopkinsRheum @CaoilfhionnMD. Not surprised to see GC, RTX, MMF affect vax. @Rheumnow
Eric Dein ejdein1 ( View Tweet)
#EULAR2021 Present6882 - Dr. Nikiphorou on diet and RMD: "The Western Diet can be called the greatest enemy of chronic inflammatory conditions." @RheumNow. https://t.co/vWeiyJkbgX
Eric Dein ejdein1 ( View Tweet)
#EULAR2021 pres6882. Uh oh. @RheumNow Drink in moderation and try green tea, it’s anti-inflammatory! https://t.co/ubYYRO3mMy
Eric Dein ejdein1 ( View Tweet)
A better way to fight cancer. Your molecular profile may reveal what treatments may be the most effective in your fight. #CarisCares #PrecisionMedicine #CancerCare
Caris Life Sciences carisls ( View Tweet)
#EULAR2021 Pres6882 @Rheumnow. Excellent summary slide by Dr. Elena Nikiphorou with 10 great take-home messages to share with your patient on diet and rheumatic disease. https://t.co/N7mq73KzLF
Eric Dein ejdein1 ( View Tweet)
EULAR Best Abstracts - Day 2 #EULAR2021
https://t.co/X0WZgpclRC https://t.co/f3pFNhoMIR
Links:
Dr. John Cush RheumNow ( View Tweet)
RheumNow’s expanded coverage of the #EULAR2021 Annual meeting is sponsored in part by Novartis, Bristol Myers Squibb, and Janssen. All content chosen by RheumNow & its Faculty.
Dr. John Cush RheumNow ( View Tweet)
Which patients with psoriasis are at risk to develop PsA?
The potential transition from psoriasis (PsO) to psoriatic arthritis (PsA) has not been a strong focus for several years but is gaining momentum.
https://t.co/5sj5HSnke3 https://t.co/NwoIoDH5rC
Links:
Dr. John Cush RheumNow ( View Tweet)
#EULAR2021 LB0004: Secukinumab for enthesitis-related JIA treatment-withdrawal study shows longer time to flare and decreased flares compared to PBO @Rheumnow https://t.co/LG3dDmH7we
Eric Dein ejdein1 ( View Tweet)
#POS0022 prosp study of CTZ pregnancies: 1392 preg w/1425 outcomes @UCBUSA database
88.4% live births, 10.5% preg loss, 0.8% still birth
2.4% congen malform (w/2.1% major)
Preg loss⬅️Crohn's, NSAIDS, MTX
Preterm labor⬅️GCs, maternal infx
⬇️birth wt⬅️RA & GCs @rheumnow #EULAR2021 https://t.co/qnNcDIz8Ge
k dao KDAO2011 ( View Tweet)
JUNIPERA - secukinumab in enthesitis related arthritis and juvenile PsA
⭐️achieved JIA ACR response compared to placebo
⭐️⬇️time to flare
⭐️75% with resolution of enthesitis
⭐️0 deaths, AE - minor infections, GI issues, headache
Abs#LB0004
#EULAR2021 @RheumNow
Robert B Chao, MD doctorRBC ( View Tweet)
SPIRIT-P1&P2 studies showed IXE effective in treating axPsA. When do you consider IL17i in your treatment algorithm in axPsA (as the predominant domain?) Poster #POS1045 #EULAR2021 @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
What's your ideal anti-rheumatic diet? #EULAR Pres6882 @Rheumnow @andreafava
Eric Dein ejdein1 ( View Tweet)
Real-world data from PsABio: 🚺generally start biologics in a worse PsA state than🚹. Although treatment improvements were similar between sexes, 🚺remained in worse health at 1 yr, and stopped/switched bDMARD earlier. Abstract #OP0232 #EULAR2021 @RheumNow https://t.co/oIGu0HzisQ https://t.co/uLnYOq8ypx
Links:
Dr. Rachel Tate uptoTate ( View Tweet)