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Do look out for Abst #OP0057 today 2/6/21 1645 CEST #EULAR2021. We propose a data-driven algorithm for #rituximab maintenance in #ANCA #vasculitis to avoid excessive retreatment and low IgG @RheumJArn @edvital P. Emery @LeedsMedHealth @LTHTResearch @LeedsHospitals @LeedsBRC https://t.co/XRR0NFnpMu
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Don’t forget to detect cardiac abnormalities in your #RA and #PsA patients! Systematic transthoracic echocardiogram show higher prevalence of diastolic dysfunction, mild mitral and pulmonary valve regurgitation vs. matched controls. #EULAR2021 @RheumNow #POS1392 https://t.co/UsvbEKBRUY
Aurelie Najm AurelieRheumo ( View Tweet)
Result from the #EULAR2021 recommendations on management of RMD in COVID update SLR: No evidence that people with RMDs present an increased risk of contracting COVID19, consistent with the initial Recos. @RheumNow https://t.co/2Q0s3ZKJOP
Aurelie Najm AurelieRheumo ( View Tweet)
🚨So after LoVAS
Now this
Ritux + MMF + Pulse MPS
No oral steroids 🤯
@ARD_BMJ
@EBRheum - Lesser is better ??
https://t.co/CYMNX8wLtd https://t.co/NtwTas3ZdS
EnvisionRheumat ERheumat ( View Tweet)
Positive RCT of Rituximab in Systemic sclerosis https://t.co/WsDZeollu0
Richard Conway RichardPAConway ( View Tweet)
Oh, this is a bummer. #EULAR2021 @RheumNow https://t.co/abdEXPU3Bh
Eric Dein ejdein1 ( View Tweet)
Dr Atienza-Mateo presents on IFX ADA TCZ in Behcets refractory uveitic cystoid macular oedema. All appear effective! @RheumNow #EULAR2021 Abstr#OP0060 https://t.co/Vpju0IvrC5
Richard Conway RichardPAConway ( View Tweet)
Dr Mekinian presents data showing TCZ and TNFi appear equally effective in TAK, complete response 66% vs 70% at 6 months @RheumNow #EULAR2021 Abstr#OP0068
Richard Conway RichardPAConway ( View Tweet)
Dr Kragsnaes presents counter-intuitive data on the gut microbiome. Faecal microbiota transplant ineffective in treating active peripheral psoriatic arthritis, leading to WORSE outcomes. But maybe this also tells us something? @RheumNow #EULAR2021 Abstr#OP0010 https://t.co/nvDvO4Gfxc
Richard Conway RichardPAConway ( View Tweet)
Promising preclinical data of novel dual BAFF/APRIL inihibitor ALPN-303 re:efficacy & immunomodulatory activity vs TACI-i. Could deplete plasma cell compared to anti-CD20 mAbs in #SLE. Be interesting to see how it’ll fare in future clinical trials #EULAR2021 #OP0039 @RheumNow https://t.co/LnQzO67gwI
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Dr Sanchez-Bilbao presents surprising data that tocilizumab may improve even permanent vision loss in GCA @RheumNow #EULAR2021 Abstr#OP0065 https://t.co/oFGNZ04oKr
Richard Conway RichardPAConway ( View Tweet)
ProDERM OP0008: IVIG 2g/kg q4w for dermatomyositis vs PBO, open-label extension. TIS score responders 78% vs 43%. IVIG great option: Not immunosuppressive and works fast, watch for headache, pyrexia, nausea, risk of VTE. #EULAR2021 @RheumNow https://t.co/m4CEkg3EyC
Eric Dein ejdein1 ( View Tweet)
We know smoking is ass w/ RA. How about passive 🚬? French E3N-EPIC cohort: OP0012. Prospective questionaries of 80,000F, 698 incident cases. ⬆️ risk in passive childhood and adult tobacco exposure. #EULAR2021 @RheumNow 🚭! https://t.co/1Rf0euz3VC
Eric Dein ejdein1 ( View Tweet)
OP0010 at #EULAR2021. FLORA trial: Fecal microbiota transplant as add-on Rx to MTX. Small trial showing time-to-event curves show inferiority to sham but good safety. Fascinating concept exploring gut-joint interaction. @RheumNow. https://t.co/BIOmA5z6vK
Eric Dein ejdein1 ( View Tweet)
Some interesting abstracts at #EULAR2021 today on monitoring GCA with:
- ultrasound
OP0055 https://t.co/0fqLIK5IPV
- PET/CT
OP0069 https://t.co/WQl9VaHR9E
OP0064 https://t.co/w7biFT6qy0
What do you believe is the most accurate measure of true disease activity in GCA? @RheumNow
Links:
David Liew drdavidliew ( View Tweet)
Dr Arnold @Yuz6Yusof present on personalised rituximab retreatment in AAV. Interesting that naive B-cell repopulation at 6 months predicts better sustained response compared to absence @RheumNow #EULAR2021 Abstr#OP0057 https://t.co/cypyQVMeYz
Richard Conway RichardPAConway ( View Tweet)
IVIG pending FDA review for tx of dermatomyositis after ProDERM study. Do you use IVIG for tx of DM?
#EULAR2021 @RheumNow
Robert B Chao, MD doctorRBC ( View Tweet)
ProDERM RCT IVIG in Dermatomyositis
⭐️improved TIS scores compared to pbo
⭐️common AE: headaches, pyrexia, nausea
⭐️serious AE: PE, CVA, DVT
⭐️approved in Europe, pending FDA
Abs#OP0008
#EULAR2021 @RheumNow
Robert B Chao, MD doctorRBC ( View Tweet)
Comparison of disease activity and PROs in AxSpA vs. AxPsA
⭐️AxSpA ⬆️ uveitis and IBD
⭐️AxPsA ⬆️enthesitis and dactylitis
⭐️AxSpA pts ⬆️pain, spinal pain PROs
⭐️Fatigue and work impairment did not differ in AxSpA vs AxPsA
Abs#OP0049 #EULAR2021 @RheumNow https://t.co/wGD6IA5ahb
Robert B Chao, MD doctorRBC ( View Tweet)
@jeffsparks knocking it out of the park presenting our findings on b/tsDMARD associations with COVID-19 outcomes @eular_org @EULAR_Press check out our full paper just published in @ARD_BMJ https://t.co/jcA1LN45R3
Zach Wallace zach_wallace_md ( View Tweet)