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ANCA, vasculitis, test

Avacopan for ANCA Vasculitis Goes in Front of the FDA

d MedPage Today

An FDA advisory panel will consider whether to recommend approval of an oral C5a inhibitor for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, with agency staff raising questions over the "clinical meaningfulness" of key study data.

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RheumNow Podcast – Falling or Falling in Love?

d Jack Cush, MD

Dr. Jack Cush reviews the best journal articles from the past week on RheumNow.com.

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Unique Oral Microbiome in Early and Pre-Clinical RA

d Jack Cush, MD

An oral microbiome study of rheumatoid arthritis patients suggests that periodontal condition in patients with early rheumatoid arthritis and individuals at risk of RA.

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ARTIC REWIND - Don't Half DMARD Therapy

d Jack Cush, MD

The ARTIC-REWIND study examined rheumatoid arthritis (RA) patients in remission on conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) to see if they could "step-down" their csDMARDs theray; but  the study showed that 25% those who went on half-dose experienced disease fl

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Level, monitor, calculate, glucose, diabetes

Drug Monitoring Ineffective with Infliximab Treatment

d Jack Cush, MD

The predictive value of therapeutic drug monitoring (TDM) while on biologics is debateable; gastroenterology routinely relies on TDM, while rheumatologists do not.

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News Feature: Drug Monitoring Ineffective with Infliximab Treatment A randomized trial compared TDM to no TDM in patients receiving infliximab for chronic IMIDs and found that TDM did not increase the odds of achieving remission. https://t.co/AVcX4EXY0l https://t.co/RlDij6ln61

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Falls are not uncommon in #RA patients; significant risk factors for falls include being elderly, un-married, higher pain scores, reported dizziness taking psychotropic medications and having lower HRQoL scores https://t.co/a8qA7n68q5

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Dr. John Cush RheumNow ( View Tweet)

Today begins National Nurses week! God Bless Rheumatology Nurses https://t.co/JC9ExqnXEb #ArthritisAwarenessMonth https://t.co/bhuocIlHWT

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Dr. John Cush RheumNow ( View Tweet)
News Feature: Childhood Lupus May Hamper Adult Careers Long-term outcomes of kids with cSLE are uncommon, but this cSLE cohort analysis suggests that SLE significantly impacts their future education, vocation, and employment as they reach adulthood. https://t.co/RQc4JD3BIt https://t.co/l0ZQWHNFng

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#LupusAwarenessMonth Dr. Kathryn Dao - Pregnancy Outcomes in Lupus, SpA From ACR 2020 https://t.co/TvlqwZqgOv https://t.co/UBeVghYh0g

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Dr. John Cush RheumNow ( View Tweet)
Join us each Tuesday for Tuesday Night Rheumatology. We'll have new speakers each week and a Q&A session available following the discussion. https://t.co/ugGaPvBsLD https://t.co/CCua5Uvl7f

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Dr. John Cush RheumNow ( View Tweet)
Study of healthcare resource utilization and costs psoriasis, psoriatic arthritis (PsA) vs controls; PsA has the highest annual all-cause healthcare costs per patient - Controls =$7,470, Psoriasis= $11,062, and PsA = $29,742 https://t.co/06irRupcLJ

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Dr. John Cush RheumNow ( View Tweet)

Systematic review 6 studies of ischemic stroke and Idiopathic inflammatory myopathies (IIM) shows among 5,114 IIM cases there was an increased risk of ischemic stroke (RR = 2.41, 95% CI: 1.31, 4.45), 49% higher in dermatomyositis and Asian IIM. https://t.co/gYdMgmU5Uh

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Dr. John Cush RheumNow ( View Tweet)

News Feature: Autoimmune Thyroid Disease in Women JAMA has posted an insights article reviewing autoimmune thyroid disease in women. Thyroid autoimmunity has a higher prevalence in women and with increasing age. https://t.co/P55lMMagyO https://t.co/yMWJClvVJO

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Dr. John Cush RheumNow ( View Tweet)
Did you miss last night's Tuesday Night Rheumatology? Watch the playback now. https://t.co/8fjseHpSQV https://t.co/x4NSftQuRQ

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Dr. John Cush RheumNow ( View Tweet)
News Feature: Results Disappoint for Fecal Transplant in Arthritis Fecal microbiota transplantation (FMT) showed disappointing results among patients with active psoriatic arthritis, a small randomized trial found. https://t.co/US96DAa9XR https://t.co/IzWZJJe1RX

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Dr. John Cush RheumNow ( View Tweet)
May is Lupus month! We've compiled some great lupus resources to share throughout the month. #LupusAwarenessMonth Dr. Janet Pope - Modifying risk of Lupus and RA From ACR 2020 https://t.co/f8a6vHB31e https://t.co/8jteX3F5qg

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Dr. John Cush RheumNow ( View Tweet)
Belimumab now approved in the EU for lupus nephritis. The EMA has approved intravenous and subcutaneous Benlysta (belimumab) in combination with background immunosuppressive therapies for adults with active lupus nephritis https://t.co/Twbe1ClT5w

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Dr. John Cush RheumNow ( View Tweet)

TNF inhibitor induced (paradoxical) psoriasis in JIA patients was 3 fold higher when TNFi was used - data from 8,222 children in the CARRA registry (54% used TNFi) - rate 8.5 cases/1000PY. https://t.co/HKpAEbtNqr https://t.co/txvmGfpdWf

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Dr. John Cush RheumNow ( View Tweet)

27 cases of #immune-mediated diseases post #COVIDVaccination ▶️21 had autoimmune/rheumatic background ▶️17 flares, 10 new onset ▶️Average 4 days post #covidvaccine ▶️>80% had resolution, mostly with corticosteroid 👉🏽https://t.co/zHlFziswU7 via @Vaccines_MDPI @MDPIOpenAccess https://t.co/5ifoBmb9Ux

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Dr Ai Lyn Tan DrAiLynTan ( View Tweet)
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