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Open Access Risk Factors for Dementia in Patients With Incident Rheumatoid Arthritis: A Population-Based Cohort Study đź“° https://t.co/reGuRVPQSG #dementia #rheumatoidarthritis https://t.co/0K7URVTkYO

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The Journal of Rheumatology jrheum ( View Tweet)
Dr. Kristi Kuhn & Univ of Colorado researchers have linked RA risk with the gut bacterium Subdoligranulum didolesgii. This could be pathogenically important and supports their "Mucosal origins hypothesis" to RA risk https://t.co/EMfNzWSPBK https://t.co/dp7p6vMI4W https://t.co/E1CBUPy2Wp

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Dr. John Cush RheumNow ( View Tweet)
Dr. Kristi Kuhn & Univ of Colorado researchers have linked RA risk with the gut bacterium Subdoligranulum didolesgii. This could be pathogenically important and supports their "Mucosal origins hypothesis" to RA risk https://t.co/EMfNzWSPBK https://t.co/dp7p6vMI4W https://t.co/E1CBUPy2Wp

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Dr. John Cush RheumNow ( View Tweet)
RheumNow Podcast square

2022 Rheumatology Year in Review (1-6-2023)

d Jack Cush, MD

Dr. Jack Cush reviews the best of 2022 in Rheumatology - highlights on new drug indications, breakthrough lupus therapies, new biosimilars and the multivitamin letdown.

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Join us for RheumNow Live this March 18-19 in Dallas, TX! We're not like other meetings--we're answering the questions you want answered. RNL is a meeting to engage your mind and change your practice. Join us in-person or virtually! https://t.co/bMphD12Bie https://t.co/Hx0uHAIUWd

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Dr. John Cush RheumNow ( View Tweet)
2022,wordle

2022 Rheumatology Year in Review

d Jack Cush, MD

2022 was a year of recovery, discovery, and some losses.  While still dealing with the aftermath of COVID-19, rheumatologists were resilient as leaders for their patients and research in advancing rheumatologic care.

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Dr. Kristi Kuhn & Univ of Colorado researchers have linked RA risk with the gut bacterium Subdoligranulum didolesgii. This could be pathogenically important and supports their "Mucosal origins hypothesis" to RA risk https://t.co/xDyejVR8MW https://t.co/M663ziXOcT https://t.co/y7zpukZah5

Links:

Dr. John Cush RheumNow ( View Tweet)
Dr. Kristi Kuhn & Univ of Colorado researchers have linked RA risk with the gut bacterium Subdoligranulum didolesgii. This could be pathogenically important and supports their "Mucosal origins hypothesis" to RA risk https://t.co/xDyejVR8MW https://t.co/M663ziXOcT https://t.co/y7zpukZah5

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Dr. John Cush RheumNow ( View Tweet)
Rheums manage #RA. But patients have to manage RA and their lives - I wish we could provide better guidance to our patients about Life with RA. Heres one patient from Wash, DC who accomplished SO MUCH in 2022 and she has RA! @hirokonishimura https://t.co/QStFGZLsTR https://t.co/Q7GoYQYvwx

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Dr. John Cush RheumNow ( View Tweet)
2002-2019 Canadian study of Rheumatology care: access has improved but problems exist, esp w/ DMARD use. In 112,494 new RA pts, 84% saw Rheum <1yrs w/ 43% increase by 2019. Suboptimal DMARD use in elderly improved 55 to 69% https://t.co/tpv514P0GP https://t.co/AIRuf7u60d

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Dr. John Cush RheumNow ( View Tweet)
608 EARLY RA pts in BARFOT study had Xrays over time. 24% did not show Erosions after 8 yrs. Pt w/ NO Erosions were younger, younger, w Less ACR criteria, & seronegative at Dx. They had more TJC, less SJC, lower ESR, less DMARDs & pred Rx. https://t.co/5jYNd7bwE3 https://t.co/z3Y0TPJTwd

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Dr. John Cush RheumNow ( View Tweet)
FDG-PET Scan in RA? Study of 34 #RA pts shows PET uptake (SUV scores) measures were significantly correlated with the number of swollen joints, SDAID but not the CDAI, disease duration, seropositivity, or RA treatments. https://t.co/AkGhEiNqwt https://t.co/FkKh49KYyd

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Dr. John Cush RheumNow ( View Tweet)
Best of 2022: Was this a Mistake? HCQ Dose Reductions per AAOS Guidelines https://t.co/Swf5kq6VtG https://t.co/UTIaCFpAX6

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Dr. John Cush RheumNow ( View Tweet)
Approximately 61% of patients with rheumatoid arthritis or psoriatic arthritis who use methotrexate report side effects following weekly dosing, including fatigue and nausea, according to data published in Rheumatology and Therapy https://t.co/k7hhdbIhW1 https://t.co/GiaihMGnWK

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Dr. John Cush RheumNow ( View Tweet)
computer screen safety

Best of 2022: Methotrexate Side Effects

d Jack Cush, MD

Data came from the UK Rheumatoid Arthritis Medication Study (RAMS), a prospective cohort of early RA patients starting methotrexate (MTX) shows that in the first year, adverse events (AE) were common, but not serious.

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No Special Heart Risk With JAK Inhibitors, Study Finds Patients taking JAK inhibitors for RA experienced similar cardiovascular outcomes as those using the TNF blocker adalimumab (Humira), analysis of French national registry data indicated. https://t.co/i0oUoTSmqF https://t.co/qrJMQbpqus

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Dr. John Cush RheumNow ( View Tweet)
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Best of 2022: EULAR 2022 Top 10 Abstracts

d Jack Cush, MD

Dr. Jack Cush reviews the top abstracts from EULAR 2022  As chosen by me with the aid of the RheumNow EULAR faculty. “Top” is relative and subjective, but my criteria for inclusion are based on impact, water cooler talk potential, innovation and social media buzz.  Speaking of social media…

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undifferentiated,arthritis,early,RA

Best of 2022: Undifferentiated Arthritis Does Not Follow an RA Course

d Jack Cush, MD

Undifferentiated arthritis (UA) is common in medical practice and many advocate early use of DMARDs; yet a recent study shows that despite DMARD use, UA patients do not fair well with this approach.

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MTX side effects more prominent in PsA than RA pts. Study of 240 PsA &amp; 86108 RA pts starting either MTX or TNFi. TNFi AE same betw PsA &amp; RA, but MTX adverse greater in PsA (44.8% vs. 29.4%), especially N/V, abdominal pain, depression, tinnitus https://t.co/qpGYDguYBK https://t.co/KUNQrSBNO2

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Dr. John Cush RheumNow ( View Tweet)
73-87% of autoimmune (RA, SLE, UCTD, APL) pts used HCQ during pregnancy. HCQ significantly reduced pre-eclampsia (20% vs 9%), early-onset pre-eclampsia (8% vs 2.5%), 2nd/3rd trimester pregnancy loss (3% vs. 0.6%) https://t.co/CF5ivHeCmY https://t.co/CYqaCCuZJz

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Dr. John Cush RheumNow ( View Tweet)

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