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My axSpA patients often ask me whether whether it's the weight loss that matters, or just exercise.
Some answers from @rheum_cat - BMI itself does matter in AS. Another one chalked up for the obesity-related inflammasome!
#ACR20 ABST1883 @RheumNow https://t.co/oMOqA8ypTt
David Liew drdavidliew ( View Tweet)
Lots of interesting studies in Spondyloarthritis including AxSpA and PsA at #ACR20 @RheumNow https://t.co/tIyqyMdmTf
Dr. Antoni Chan synovialjoints ( View Tweet)
When discussing pregnancy outcomes with your axSpA patients, do you address potential outcomes related to disease in addition to medication concerns? #ACR20 @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
Watch my interview with Dr Sinead Maguire @Sineadm15 on her SLR and meta-analysis on pregnancy in AxSpA presented at #ACR20 abstr#1323 @rheumnow @bososhea @FionaWilsonf @tomkodwyer https://t.co/E58rhIUZA4
Richard Conway RichardPAConway ( View Tweet)
Adverse pregnancy outcomes risk factors in spondyloarthritis
1⃣Most common - GSA
2⃣IBD symptoms, aggressive/active disease ⬆️risk
3⃣No difference in age or steroid use
Healthy mom, healthy baby.
@RheumNow #ACR20 Abs#1324
Robert B Chao, MD doctorRBC ( View Tweet)
Thinking of your last 20 consecutive Axial SpA patients in your clinic, which was the commonest extra-articular manifestation that you encountered? @RheumNow #ACR20 Abstr#1312
Dr. Antoni Chan synovialjoints ( View Tweet)
Are there distinct groups of axSpA and PsA patients with peripheral arthritis. This study shows heterogeneous patterns of peripheral involvement and overlap in SpA and PsA groups @RheumNow #ACR20 Abstr#1311 https://t.co/2Q5FH6ZrWm
Dr. Antoni Chan synovialjoints ( View Tweet)
Detection of inflammatory back pain (IBP) is important for the early diagnosis of Axial SpA. Which IBP criteria do you use in your clinic? @RheumNow #ACR20 Abst#1303
Dr. Antoni Chan synovialjoints ( View Tweet)
Pregnancy outcomes in women with AxSpA
4 prospective cohorts in Europe
328 total pregnancies
Favorable outcomes overall
1⃣3% pre-eclampsia
2⃣6-9% gestational DM
3⃣0-5% preterm birth rates (similar to WHO rate 9% in Eur)
@RheumNow #ACR20 Abs#1498
Robert B Chao, MD doctorRBC ( View Tweet)
Exploring new mode of action for treatment of AS. In BE AGILE study, Bimekizumab (BKZ) provides further sustained long-term improvements post 48 weeks in key efficacy outcome measures to 96 weeks of treatment @RheumNow #ACR20 Abstr#1364 https://t.co/972AvDNJDq
Dr. Antoni Chan synovialjoints ( View Tweet)
In the current era, would a positive treat-to-target study in AS change your approach to practice?
(TICOSPA trial ABST1444) #ACR20 @RheumNow
David Liew drdavidliew ( View Tweet)
Check out my video on T2T in SpA abstracts from #ACR20 @RheumNow https://t.co/ZBvmhWyDHU
Dr. Rachel Tate uptoTate ( View Tweet)
Network Meta-Analysis of JAK and TNF Inhib in 19 AS studies (3,654pts) showed best results with TNFi (golimumab and infliximab) but JAKs also appear to be effective option. #ACR20 Abstr#1357 #UTSW @AdelaCastro222 https://t.co/HnnPD6eXW5 https://t.co/Li30kkp3P1
Dr. John Cush RheumNow ( View Tweet)
RheumNow’s expanded coverage of the annual #ACR2020 meeting is sponsored in part by @bmsnews, @HorizonNews, @SanofiGenzyme, @Novartis. All content chosen by RheumNow & its Faculty.
Dr. John Cush RheumNow ( View Tweet)
axSpA patients have higher rates of c-section, pre-eclampsia, IUGR and fetal complications vs normal population. Findings from a meta-analysis/systematic review #ABS1323 #ACR20 @RheumNow https://t.co/Ya9r0td7Ev https://t.co/miNURP6bOK
Dr. Rachel Tate uptoTate ( View Tweet)
Distinct gut microbiome in Ankylosing Spondylitis and AS-IBD patients compared with IBD and healthy controls.
1⃣Different alpha and beta-diversity in AS pts vs. IBD
2⃣TNFi use ➡️differentiation microbiome in IBD pts
@RheumNow #ACR20 Abs#1310 https://t.co/AGZbJZ9jtR
Robert B Chao, MD doctorRBC ( View Tweet)
Both fat mass and fat free mass have an impact on the response to bDMARDs after 6 months of treatment in AS pts. No tx response changes w/ skeletal muscle mass, visceral fat as well as water components. #ABS1376 #ACR20 @RheumNow https://t.co/oIdE8qvJPp https://t.co/wlXFf8esey
Dr. Rachel Tate uptoTate ( View Tweet)
In patients with Crohn's disease (CD), the presence of HLA-B27 and higher clinical activity of CD were associated with presence of SpA. SpA was present in 21% of early CD patients @RheumNow #ACR20 Abstr#1308
Dr. Antoni Chan synovialjoints ( View Tweet)
#ABS1303 shows ASAS modification of Berlin algorithm showed optimal balance between sensitivity and specificity and represented the preferred referral strategy for patients presenting w/ undiagnosed back pain & extra-articular features. #ACR20 @RheumNow https://t.co/10VdKC3E75 https://t.co/RgC7K3V8TB
Dr. Rachel Tate uptoTate ( View Tweet)
For all your nr-axSpA fanatics, there's a fantastic poster on certolizumab response in nr-axSpA stratified by MRI and CRP status #ACR20 @steverheum_hall https://t.co/WI1vdMItUO https://t.co/JnvAyyClDu
Dr Philip Robinson philipcrobinson ( View Tweet)
