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ACR Best Abstracts - Day 1
The RheumNow faculty reporters have been glued to their monitors all day, viewing video, reading and listening to abstract presentations and I charged them to earmark those presentations were the “Best” they saw today. Below is the list of most often noted #ACRbest abstracts from Day 1.
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Axial Involvement in Psoriatic Arthritis: Perspective by Dr. Eric Ruderman @JointMD
Dr. Eric Ruderman, Chicago, IL., provides his perspective on ACR 2020 coverage of axial involvement in Psoriatic Arthritis.
https://t.co/VwrQgirJnE
Dr. John Cush RheumNow ( View Tweet)
@drdavidliew @MGHrheumatology @RheumNow That is so interesting. Haptoglobin first described by Paolaggi et al in early 1980s as having potential to monitor PMR/GCA even when ESR normalised. See link here...
https://t.co/ERkhUwssox
Dr Sarah Mackie Sarah_L_Mackie ( View Tweet)
If TCZ blunts CRP a lot/ESR a fair bit, how can we pick GCA relapses in pts on TCZ?
Cool tech (mass spec w tandem mass tag multiplex) on GiACTA samples. Of 344 candidate proteins, guess what ranked highest?
Haptoglobin.
Let's validate!
@MGHrheumatology #ACR20 ABST0513 @RheumNow https://t.co/ErmqZuf2iu
David Liew drdavidliew ( View Tweet)
@LCalabreseDO @cappelliMD @MarieKostine @EladSharonMD @rheum_covid For those who missed it, my attempt to capture some of it in a Twitter thread: https://t.co/Z55sV7ZyBt
David Liew drdavidliew ( View Tweet)
Tailoring treatment of psoriatic arthritis
#ACR20 @RheumNow
https://t.co/Ytv0vDrd95
Robert B Chao, MD doctorRBC ( View Tweet)
Check out my video on @rheumnow! #ACR20 Non-radiographic axSpa ACR Abstracts: Dr. Rachel Tate https://t.co/TVDdyZvOEA via @YouTube
Dr. Rachel Tate uptoTate ( View Tweet)
Important study helping dissect the JAK-IFN axis I believe - we need to be cautious in attacking this axis as anifrolumab has >2x Zoster of JAKi's- we need to read the tea leaves from IEIs and COVID-19 #ACR20 @JYazdanyMD @Lupusdoc @casanova_lab @cannalab1 https://t.co/scI13jwFZd
Leonard Calabrese LCalabreseDO ( View Tweet)
Abst#0170 at #ACR20 used a process called design thinking (adopted from engineering) to build a comprehensive decision aid that takes into account preferences of both patients & providers. The future of shared-decision making? @RheumNow https://t.co/DDIqm6SQev
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Axial Involvement in Psoriatic Arthritis: Perspective by Dr. Eric Ruderman @JointMD
Dr. Eric Ruderman, Chicago, IL., provides his perspective on ACR 2020 coverage of axial involvement in Psoriatic Arthritis.
https://t.co/VwrQgirJnE
Links:
Dr. John Cush RheumNow ( View Tweet)
Scoring hand x-rays for Sharp scores is painfully tedious and not always perfectly consistent.
Why not get a computer to do it? Turns out you can - a deep adaptive machine learning model does as well as a human, each x-ray in literally one second.
#ACR20 ABST0493 @RheumNow https://t.co/SvqkaFy8XZ
David Liew drdavidliew ( View Tweet)
You can watch study group sessions that you were unable to get into by clicking on the session to access the recording! #ACR20 @RheumNow https://t.co/HdFthToKQ7
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Zonulin levels ⬆ in pre-RA/RA pts; activation of zonulin signalling leads to ⬆ intestinal permeability.
Leaky gut - potential therapeutic target for RA?
@RheumNow #ACR20 abs#492 https://t.co/C4TVrWwcYG
sheila RHEUMarampa ( View Tweet)
RheumNow’s expanded coverage of the #ACR20 Annual meeting is sponsored in part by @Novartis. All content chosen by RheumNow & its Faculty.
Dr. John Cush RheumNow ( View Tweet)
If you are using PROs for Psoriatic Arthritis in clinic, listen to the session #ACR20 #2F044 Dr. Walsh sets out the pros and cons of PROs. The key things are patient and provider buy in, integrated IT system operability and avoid PROs fatigue and burden @RheumNow
Dr. Antoni Chan synovialjoints ( View Tweet)
UK Biobank data: RA is associated with not just restrictive but also *obstructive* patterns on spirometry/PFTs (independent of smoking).
Consistent observation; direction of causality? The lung in RA continues to fascinate.
Prisco @jeffsparks et al #ACR20 ABST0491 @RheumNow https://t.co/LcjtAefnVF
David Liew drdavidliew ( View Tweet)
Among a 402 pt PSS cohort, 10% fmet 2019 EULAR/ACR SLE Criteria. SSc-SLE overlap pts more likely to be female, AfricanAmerican, limited cut.SSc, U1RNP and have similar rates of severe SSc-specific organ damage /mortality. #ACR20 Abstr#0401 https://t.co/CVcFyx9AxS https://t.co/3SAKZ9CZGS
Dr. John Cush RheumNow ( View Tweet)
@RheumNow #ACR20 abs0083 Whole exome sequencing & HLA allele prediction in 43 Irish CNO pts show increased association w/HLA-B*27:05 (+in 17.5% pts vs 6% of the Irish population). 18.6% w/personal &18.6%family Hx of PSO. 88% of cases w/multifocal disease, 51% failed 1st line Rx
Olga Petryna DrPetryna ( View Tweet)
Better outcomes (ASAS20 and ASAS40 @wk 52) seen in younger pts (possibly lower disease duration) when Secukinumab was given to ankylosing spondylitis pts. Early Dx in #AS! #ACR20 Abstr#0350 https://t.co/EKks0b1upc https://t.co/bxIH9lloI1
Dr. John Cush RheumNow ( View Tweet)
Olmstead County (Mayo) population study shows 47 lupus nephritis (LN) pts betw 1976-2018. Incidence doubled from 1980s (0.6 per 100K) to 2018 (1.2/100K); with women of childbearing age as the most affected group. #ACR20 Abstr#0274 https://t.co/uhAMd0EtJl
Dr. John Cush RheumNow ( View Tweet)