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Diagnostic Delay in Psoriatic Arthritis: What are the Consequences?
Despite increased awareness and better diagnostic modalities at hand, early diagnosis of psoriatic arthritis (PsA) still remains a huge unmet need.
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#ACR20 2F042 Dr. Grainger on COVID around the world. 1) Control disease 2) Limit steroids 3) Keep studying 4) Address disparities and 5) Advocate for your pts! @RheumNow We can get under control like in Dr Grainger's home of NZ! https://t.co/YSFxXGAiRY
Eric Dein ejdein1 ( View Tweet)
Rx in RA should be for LONG term #bestinclass #ACR20 abstr#222 shows in both bionaive & bioexperienced in 5471 pts #JAKi had more pts continuing Rx than #TNFi and other bDMARDs Not RCT & Longer durability data are needed @RheumNow @CRASCRRheum https://t.co/Uo4p5zo6gT
Janet Pope Janetbirdope ( View Tweet)
56 systemic JIA pts treated with anakinra (2.5mg/Kg/d). Pts were genotyped for 6 SNPs (from untranscribed reg IL1RN). Homozygotes >=1 SNPs associated with higher IL-1RN levels and 6 fold risk of anakinra nonresponse. #ACR20 Abst 172 https://t.co/0UU3gDfHvE
Dr. John Cush RheumNow ( View Tweet)
FAT is OK!
Abstr#0485 #ACR20 @rheumnow PROTECT-RA
150 pts cardiac CTA study:
nonobese low LDL (<70) had ⬆️plaque burden, ⬆️ LDL oxidation compared to obese low LDL pts
nonobese low LDL compared to nl LDL had 8X risk for CVD. not seen w/obese pts
DAS28 scores make no difference https://t.co/gDIS7fEY6Y
k dao KDAO2011 ( View Tweet)
Dr Christ reports on GUSTO study showing that 13/18 GCA patients treated with tocilizumab and only 3 days of steroid maintained remission at 24 weeks. @rheumnow #ACR20 Abstr#515 #ACRbest https://t.co/VLgXEUIi1c
Richard Conway RichardPAConway ( View Tweet)
Which has better durability in RA? @RheumNow @CRASCRRheum #ACR20 abstr#222
Janet Pope Janetbirdope ( View Tweet)
If the presence of fibromyalgia correlates with clinical outcome scores in psoriatic arthritis (PsA), how do you differentiate between fibromyalgia and PsA disease activity? @RheumNow #ACR20
Dr. Antoni Chan synovialjoints ( View Tweet)
Looking forward to the "#COVID19 Around the World: Impact on #Rheumatology" session over the next hour- amazing to be reminded that @rheum_covid Global Rheumatology Alliance started with a tweet! 😀
#ACR20 @RheumNow https://t.co/t2yPfkz2Cb
Mrinalini Dey DrMiniDey ( View Tweet)
Dr Quinn presenting on tocilizumab effects on PET in GCA. Abstr#514 @rheumnow #ACR20 My concern is this, persistent low grade activity on toc that returns on stopping https://t.co/nB0C1AEjbN
Richard Conway RichardPAConway ( View Tweet)
Save your $ as starting ERA with MTX works vs initial bDMARD. 470 w ERA given Rx based on DAS. Strategies MTX, BDMARD, one to other or vice versa. Not RCT- if not needed to stepup you did well as did stepdown. Not a #gamechanger @RheumNow @CRASCRRheum abstr#221 #ACR20 https://t.co/o1L3LlpIlm
Janet Pope Janetbirdope ( View Tweet)
Ultrasound in PsA:
PsA pts with fibromyalgia were associated with higher non-MDA, CPDAI, PASDAS scores but NOT higher US scores of the joints, tendons, and entheses.
@RheumNow #ACR20 #ACRbest Abs#0315 https://t.co/dapIk1rWQm
Robert B Chao, MD doctorRBC ( View Tweet)
If the synovio-entheseal complex is important in the pathogenesis of psoriatic arthritis, how do you assess the entheses in clinic? @RheumNow #ACR20
Dr. Antoni Chan synovialjoints ( View Tweet)
Another interesting study demonstrating the use of ultrasound to assess psoriatic arthritis. In very early, DMARD naïve PsA, clinically swollen joints are associated with PD synovitis, but tender, non-swollen joints are not @RheumNow #ACR20 Abst#313
Dr. Antoni Chan synovialjoints ( View Tweet)
Following promising data presented at today's poster session, results from RELIEF #Behcets study show #apremilast leads to ↓ rates of new/recurrent/worsening oral ulcers, skin lesions & #arthritis compared to placebo at 12wks.
Abs#0512 #ACR20 @RheumNow
https://t.co/O1dstY5WlL https://t.co/0djnUGw0Hg
Mrinalini Dey DrMiniDey ( View Tweet)
Another study on rheum pt outcomes w/#COVID19: similar outcomes as nonrheum pts. MGH/JHU/Brigham 143 rheum vs 688 nonrheum. No⬆️risk in rheums after adjusting for race/smoking/comorbidities for: hospitalizations, mech ventil'n 3. ICU 4. death #ACR20 Abstr#L01 @RheumNow https://t.co/362UZUe5dg
k dao KDAO2011 ( View Tweet)
Prof Hatemi report on apremilast in Behcets disease. We know it improves oral ulcers. Now shown to improve skin lesions and arthritis. @rheumnow #ACR20 Abstr#512 https://t.co/BwIqio6dzq
Richard Conway RichardPAConway ( View Tweet)
DISCOVER-2 (52 wk study) Guselkumab 100mg q4wk and q8wk for tx of PsA 1️⃣Sustained responses in: ACR20/50/70, PASI90/100, HAQ-DI, MDA/VLDA, QoL 2️⃣Improvement enthesitis/dactylitis 3️⃣No increase rate of serious infection @RheumNow #ACR20 Abs#0506 https://t.co/7MXYTucVZ9
Robert B Chao, MD doctorRBC ( View Tweet)
The presence of fibromyalgia in psoriatic arthritis correlates with the clinical outcome scores. Ultrasound evaluation can be useful to evaluate disease activity in the presence of fibromyalgia @rheumnow #ACR20 Abstr#315 #ACRbest
Dr. Antoni Chan synovialjoints ( View Tweet)
“Rheumatology comes in as the #2 specialty utilizing teleheath in a survey by Doximity.” Dr. C. Peoples discussing teleheath and COVID-19. “The elephant in the room is the physical exam!” #ACR20 @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)