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Diagnostic Delay in Psoriatic Arthritis: What are the Consequences?
Despite increased awareness and better diagnostic modalities at hand, early diagnosis of psoriatic arthritis (PsA) still remains a huge unmet need.
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Shoutout to @SattuiSEMD and @NavarroMillanMD showing #dementia is lower in #RA pts on bDMARDs compared to csDMARDs using CMS data #ACR20 ABS#0488 @RADoctor @RheumNow https://t.co/1XOV2zqKko
Bella Mehta bella_mehta ( View Tweet)
Great talk by @rheumcat @rheum_covid on COVID-19 impact on rheumatology. Talk to pts re: what to do with rheum rx... they haven't read guidelines and may make their own changes! Prepare them for exposure/ifn! #ACR20 @Rheumnow 2F042 https://t.co/HkxbkYjEm3
Eric Dein ejdein1 ( View Tweet)
@RheumNow #acr20 abs0405 RELIF ph3 rct: pts w/Behcets who achieve Full resolution of OUs w/Apremilast by wk6+ 6wks of sustained response also report better improvement in BSAS, OU pain, overall Dis activity& QoL. Only 29.8% were able to achieve 6+6 though, while 70.2% did not https://t.co/8roaO5YPM6
Olga Petryna DrPetryna ( View Tweet)
Dr Garvey presenting on trends in GCA incidence in Olmstead County. Becoming less common year on year there. Not my experience in Ireland #ACR20 Abstr#517
@rheumnow @Sarah_L_Mackie https://t.co/3O963l6UXG
Richard Conway RichardPAConway ( View Tweet)
NEMO Deleted Exon 5 Autoinflammatory Syndrome (NDAS) is a new immunodeficiency syndr (Autosomal dom), GOF w/ paniculitis, CNS, HSM, Cytopenias, hypogamm & autoAbs. 12 described cases. Linked to upregulation of NFKB and IFN signature. #ACR20 Abst #0176 https://t.co/1k1tFbFKu1
Dr. John Cush RheumNow ( View Tweet)
Amazing table by Dr. Arthur Kavanaugh that is jam-packed with a gold mine of information reviewing therapies for RA, PsA, AxSpa, IBD, & autoinflammatory dz in a concise, high yield fashion #ACRbest #rheumtwearls #ACR20 @RheumNow https://t.co/pVaxye42jX https://t.co/z4HRtU4tmt
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
#ACR20 2F042 Dr. Grainger on COVID around the world. 1) Control disease 2) Limit steroids 3) Keep studying 4) Address disparities and 5) Advocate for your pts! @RheumNow We can get under control like in Dr Grainger's home of NZ! https://t.co/YSFxXGAiRY
Eric Dein ejdein1 ( View Tweet)
Rx in RA should be for LONG term #bestinclass #ACR20 abstr#222 shows in both bionaive & bioexperienced in 5471 pts #JAKi had more pts continuing Rx than #TNFi and other bDMARDs Not RCT & Longer durability data are needed @RheumNow @CRASCRRheum https://t.co/Uo4p5zo6gT
Janet Pope Janetbirdope ( View Tweet)
56 systemic JIA pts treated with anakinra (2.5mg/Kg/d). Pts were genotyped for 6 SNPs (from untranscribed reg IL1RN). Homozygotes >=1 SNPs associated with higher IL-1RN levels and 6 fold risk of anakinra nonresponse. #ACR20 Abst 172 https://t.co/0UU3gDfHvE
Dr. John Cush RheumNow ( View Tweet)
FAT is OK!
Abstr#0485 #ACR20 @rheumnow PROTECT-RA
150 pts cardiac CTA study:
nonobese low LDL (<70) had ⬆️plaque burden, ⬆️ LDL oxidation compared to obese low LDL pts
nonobese low LDL compared to nl LDL had 8X risk for CVD. not seen w/obese pts
DAS28 scores make no difference https://t.co/gDIS7fEY6Y
k dao KDAO2011 ( View Tweet)
Dr Christ reports on GUSTO study showing that 13/18 GCA patients treated with tocilizumab and only 3 days of steroid maintained remission at 24 weeks. @rheumnow #ACR20 Abstr#515 #ACRbest https://t.co/VLgXEUIi1c
Richard Conway RichardPAConway ( View Tweet)
Which has better durability in RA? @RheumNow @CRASCRRheum #ACR20 abstr#222
Janet Pope Janetbirdope ( View Tweet)
If the presence of fibromyalgia correlates with clinical outcome scores in psoriatic arthritis (PsA), how do you differentiate between fibromyalgia and PsA disease activity? @RheumNow #ACR20
Dr. Antoni Chan synovialjoints ( View Tweet)
Looking forward to the "#COVID19 Around the World: Impact on #Rheumatology" session over the next hour- amazing to be reminded that @rheum_covid Global Rheumatology Alliance started with a tweet! 😀
#ACR20 @RheumNow https://t.co/t2yPfkz2Cb
Mrinalini Dey DrMiniDey ( View Tweet)
Dr Quinn presenting on tocilizumab effects on PET in GCA. Abstr#514 @rheumnow #ACR20 My concern is this, persistent low grade activity on toc that returns on stopping https://t.co/nB0C1AEjbN
Richard Conway RichardPAConway ( View Tweet)
Save your $ as starting ERA with MTX works vs initial bDMARD. 470 w ERA given Rx based on DAS. Strategies MTX, BDMARD, one to other or vice versa. Not RCT- if not needed to stepup you did well as did stepdown. Not a #gamechanger @RheumNow @CRASCRRheum abstr#221 #ACR20 https://t.co/o1L3LlpIlm
Janet Pope Janetbirdope ( View Tweet)
Ultrasound in PsA:
PsA pts with fibromyalgia were associated with higher non-MDA, CPDAI, PASDAS scores but NOT higher US scores of the joints, tendons, and entheses.
@RheumNow #ACR20 #ACRbest Abs#0315 https://t.co/dapIk1rWQm
Robert B Chao, MD doctorRBC ( View Tweet)
If the synovio-entheseal complex is important in the pathogenesis of psoriatic arthritis, how do you assess the entheses in clinic? @RheumNow #ACR20
Dr. Antoni Chan synovialjoints ( View Tweet)
Another interesting study demonstrating the use of ultrasound to assess psoriatic arthritis. In very early, DMARD naïve PsA, clinically swollen joints are associated with PD synovitis, but tender, non-swollen joints are not @RheumNow #ACR20 Abst#313
Dr. Antoni Chan synovialjoints ( View Tweet)