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Christian, charles, leader, rheum

Dr. Charles Christian of HSS Honored

d Jack Cush, MD

In the current issue of Annals of Rheumatic Disease, Dr. Peggy Crow honors the life and career of one the great, historic rheumatologists of all time: Dr. Charles Christian. For those interested in the history of rheumatology, mentoring and leadership, this is a good read. For those interested in leading a truly good life, and being a real role model, this is a must read.

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back, LBP, spine, AS

Broadalumab Efficacy in Axial Spondyloarthritis

d Jack Cush, MD

Broadalumab (Siliq), an anti-interleukin-17 receptor A monoclonal antibody, is currently FDA- approved for use in adults with plaque psoriasis; but a recent trial shows it to be effective in patients with axial spondyloarthritis (axSpA).

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pompe myopathy glycogen muscle

New, Improved Therapy for Pompe Disease

d Jack Cush, MD

Researchers from the University of Cincinnati Gardner Neuroscience Institute will present data on a new treatment for Pompe disease at the American Academy of Neurology on April 20th; the results show that treatment with avalglucosidase alfa yielded substantial clinical improvements and a more favorable safety profile compared to the current standard of care (alglucosidase alfa).

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Serious problem! Pulmonologists uniformly believe that MTX causes and/or worsens ILD. MTX causes hypersensitivity pneumonitis, not ILD. RA, lupus DM, PSS cause ILD and they may need MTX to manage their disease. Do your own research, look at this paper to start. https://t.co/DHC5ikhCf6

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Dr. John Cush RheumNow ( View Tweet)

There's a special, deep hell for insurers/PBM's that give patients a hassle over paying for a cheap drug like methotrexate. And these days it's looking like it's going to be very, very crowded.

Ethan Craig rheumecraig ( View Tweet)

Another @preventiveneur1 paper just published. @tomrptaylor looked at demyelinating events reported in people taking anti-TNF in the BSRBR. We found that these events are uncommon in people with underlying rheumatological disease https://t.co/qCaF6YMLAh

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Ruth Dobson drruthdobson ( View Tweet)

#RNL2021 coverage from @doctorRBC "Biosimilars are on their way. Coming to you in 2024! They will most likely be cheaper for insurance companies, but will they be cheaper for patients? " #RheumNow

Dr. John Cush RheumNow ( View Tweet)

Join us for Tuesday Night Rheumatology with Dr. Philip Robinson and Dr. Iain McInness. We'll discuss highlight sessions for RheumNow Live 2021 #RNL2021 https://t.co/oJ4xYL32aC https://t.co/Eix01GlWoj

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Dr. John Cush RheumNow ( View Tweet)
News Feature: New, Improved Therapy for Pompe Disease https://t.co/dEZ9Y0biHu https://t.co/rXh7fH13rc

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Dr. John Cush RheumNow ( View Tweet)
Dr. R Fleischmann "Don't be afraid to use TOFA!" FDA warnings on⬆️ MACE/malign based on 1 study (Pfizer 1133) in high risk patients. Older age, tobacco use are risks for MACE/CV events and cancer. Meta-analyses, registries, clinical trials program do NOT show⬆️ risk #RNL2021 https://t.co/4p9YqyDrGz
k dao KDAO2011 ( View Tweet)
Randomized trial of 206 adults with knee OA found that a web-based exercise intervention supported by text messaging improved knee pain and function at 24 weeks vs web-based information alone. (MCID pain 72.1% vs 42%) https://t.co/h5UaedS4Zm

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Dr. John Cush RheumNow ( View Tweet)

Not in the US, but biosimilar infliximab (CT-P13) is being used subcutaneously in the EU and Canada. Analysis of 2 RCTs shows (compared to IV inflectra or remicade) SC CT-P13 greater DAS28-CRP, CDAI and SDAI response rates. https://t.co/prSVJ0BIdd

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Dr. John Cush RheumNow ( View Tweet)

Have you had the chance to listen to the latest RheumNow podcast on combination biologics? https://t.co/FFtYHhw7Qc https://t.co/YT1h8iL647

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Dr. John Cush RheumNow ( View Tweet)
News Feature: Planes, Trains and COVID Distancing MMWR reports the risk of acquiring an infection with SARS-CoV-2 is reduced 23% to 57% when the middle seat was vacant (compared with full aircraft occupancy). https://t.co/tGs9Go7DhU https://t.co/Gz9L1ERcUU

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Dr. John Cush RheumNow ( View Tweet)
News Feature: Autoimmune Risk of Death Up during COVID A population-based study in the UK shows patients with RAIRD were 44% more likely to die during the '20 COVID-19 pandemic (Mar - Apr) compared to either the general population or their pre-COVID risk. https://t.co/e1vWOjGglt https://t.co/OIaM3Hx7BO

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Dr. John Cush RheumNow ( View Tweet)
Scoot over small molecule inhibitors, the future might be with nanoparticle targeting for RA! Dr. Fleischmann reviews study on nanoparticle targeting of CCP Ab that showed noninferiority to Tocilizumab #RNL2021 coverage from @KDAO2011

Dr. John Cush RheumNow ( View Tweet)

BRAND NEW PODCAST-- Combination Biologics We talk about the articles featured on RheumNow this week. https://t.co/FFtYHhNJeM https://t.co/XCFMsZ6ttG

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Dr. John Cush RheumNow ( View Tweet)
#RNL2021 Coverage from Dr. Rachel Tate @uptoTate The good and the bad of HLA B27 iritis from Dr. Wang #RNL2021 -- 90% of patient maintain 20/40 vision or better with treatment -- BUT disease can relapse and can alternate between eyes

Dr. John Cush RheumNow ( View Tweet)

Johns Hopkins myositis clinic: anti-mitochondrial Abs (AMA) found in 5% adult myositis, 1% of juv. myositis pts. AMA assoc. w/ severe muscle weakness, Raynauds, dysphagia, cardiomyopathy & treatment refractory Dz - Screening for cardiac & swallowing https://t.co/oj9kwHgTHf

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Dr. John Cush RheumNow ( View Tweet)

News Feature: USPSTF - No Need to Screen for Vitamin D Deficiency JAMA has published the new recommendation from the USPSTF stating that screening for vitamin D deficiency is unnecessary and unwarranted in asymptomatic adults. https://t.co/njeBeGgR7f https://t.co/vedK68MS0J

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Dr. John Cush RheumNow ( View Tweet)
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