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TNF Inhibitors Reduce and Stabilize Coronary Plaque

d Jack Cush, MD

Arthritis & Rheumatology reports that biologic (bDMARD) use in rheumatoid arthritis may decrease cardiovascular disease risk by retarding coronary plaque formation and progression (especially non‐calcified and low‐attenuation plaque).

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High Dose Chloroquine Harmful in Severe COVID-19

d Jack Cush, MD

JAMA Open Network reports an interim analysis of the Brazilian CloroCovid-19 trial showing thta higher doses of chloroquine (CQ) in the treatment of severe COVID-19 was associated with QTc interval prolongation and increased mortality.

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RheumNow Podcast – In Times of Trouble (4.24.20)

d Jack Cush, MD

Dr Jack Cush reviews the news, journal reports, twitter feed and COVID developments from the past week on RheumNow.com

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How Has COVID-19 Affected You?

d Jack Cush, MD

I need your HELP and INPUT.

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"Permanence, perseverance and persistence in spite of all obstacles, discouragements, and impossibilities: It is this, that in all things distinguishes the strong soul from the weak." - Thomas Carlyle

Dr. John Cush RheumNow ( View Tweet)

Health Canada issued a safety alert noting Chloroquine & hydroxychloroquine can have serious toxicities & should only be used under a physicians supervision. Due o concern that some may be directly buying/using CQ/HCQ to treat/prevent COVID-19 https://t.co/ksxveHADZX

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Dr. John Cush RheumNow ( View Tweet)

Sanofi announced early results of phase 2 trial of IL6 inhibitor, sarilumab, showing benefit only in Critical COVID-19 pts. 457 pts given IV Kevzara 400 mg vs 200 mg vs PBO , high dose had fewer deaths (32 v 46 v 55%) & more D/C (53 v 39 v 41%). https://t.co/6q21qJNj2C

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Dr. John Cush RheumNow ( View Tweet)

On April 24, FDA issued a Drug Safety Communication stating HCQ and CQ have not been shown to be safe and effective in COVID-19 and that HCQ/CQ should not be used outside of hospitalized or pts in clinical trials. https://t.co/l2DNBhhvTR

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Dr. John Cush RheumNow ( View Tweet)

Informative, straight forward, well done video of the SHOULDER Exam! https://t.co/AQetQjvQP1

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Dr. John Cush RheumNow ( View Tweet)

"Quantity and persistence will get you the outcomes you need." - James Altucher

Dr. John Cush RheumNow ( View Tweet)

The RheumNow Podcast is up! "In times of Trouble". Watch it here>> https://t.co/gapTwq3REW or listen to the podcast on iTunes or SoundCloud>> https://t.co/dpoCoX8qBR

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Dr. John Cush RheumNow ( View Tweet)

"Yeah, you might beat me today, but then you’re gonna have to fight me again tomorrow and the day after that and every single day from now on until I kick the #$%! out of you, which I will.” - William Costanzo

Dr. John Cush RheumNow ( View Tweet)

The RheumNow Podcast is up! "In times of Trouble". ABA and DM, Zostavax fails, 3d Doubling rate, population testing, HCQ in COVID; Watch it here>> https://t.co/gapTwq3REW or listen to the podcast on iTunes or SoundCloud>> https://t.co/dpoCoX8qBR

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Dr. John Cush RheumNow ( View Tweet)

"Stay in your seat come times of trouble. Its only people who jump off the roller coaster who get hurt." - Paul Harvey

Dr. John Cush RheumNow ( View Tweet)

Perhaps love is like a resting place, a shelter from the storm. It exists to give you comfort, it is there to keep you warm, and in those times of trouble when you are most alone, the memory of love will bring you home." - John Denver

Dr. John Cush RheumNow ( View Tweet)

There’s a saying that anyone driving faster than you is crazy and anyone driving slower doesn’t know how to drive. Similar with COVID-19: anyone taking more precautions than you has an anxiety issue and anyone taking fewer is an idiot.

Adam Cifu adamcifu ( View Tweet)

Dr C Kershaw @UTSWNews grand rounds on ventilation in #COVID19 Why putting pts in prone position might help with ARDS ⁦@RheumNow⁩ https://t.co/I0AOx72Jwl
k dao KDAO2011 ( View Tweet)
ACR Guidance for Rheumatic Disease during COVID-19 pandemic #Rheumatology @RheumNow https://t.co/vHav6g4p6Q
Maeve Gamble MaeveGamble ( View Tweet)
NICE guidelines on managing rheumatologic conditions during COVID-19 #Rheumatology @RheumNow https://t.co/dQcavsno5N
Maeve Gamble MaeveGamble ( View Tweet)
Dr. Kavanaugh said it well in his blog on the "Upside of Covid" Humanity is really shining thru these days. Im truly touched by all my patients who ask about my health and my safety during COVID-19 == we all have to look out for each other! https://t.co/BYI5LHybeV

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Dr. John Cush RheumNow ( View Tweet)

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