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Anakinra in #Stills disease - Double blind, placebo controlled RCT in Stills disease total 12pts, 6 placebo, 6 Rx grp. All pts reached ACR70 at week 2 without fever and sustained it at 12 weeks. 5/6 reached ACR90 @RheumNow
#ACR20 ABS#1633 #ACRbest https://t.co/9E4vm7WzhP
Bella Mehta bella_mehta ( View Tweet)
Poll results are in! 48% of those that responded are not yet convinced of the benefits of omega-3 fish oil supplements in pts w/ RA! #ACR20 @RheumNow https://t.co/B6f8ecWj07
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Wonder if you can predict which pts you can successfully taper off bDMARDs? Abst#1538 from Denmark showed that a neg IgM-RF (OR 0.26) & low Doppler serum score for 24 jts predicted successful discontinuation of bDMARDs at 2yr f/u in RA pts w/ DAS28-CRP<2.6. #ACR20 @RheumNow https://t.co/CbJTguxaoa
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Just a reminder:
inflammatory arthritis irAEs can occur at almost any time after immune checkpoint inhibitor cancer immunotherapy is commenced.
@LoyolaChicago #ACR20 ABST1566 @RheumNow https://t.co/qdEpNpzdNs
David Liew drdavidliew ( View Tweet)
I am glad now that chloroquine is not available (permanent back order) in Canada as results of high retinal toxicity w chloroquine was sobering & changed my practice. I won’t use it long term @RheumNow #ACR20 @CRASCRRheum abstr#1825 https://t.co/1RQi41uV1B https://t.co/lc9za22Zw1
Janet Pope Janetbirdope ( View Tweet)
A large observat study showed no difference in risk of major CV events in RA pts that were newly started on either MTX or HCQ. A greater stroke risk but lower risk of MI & hospitalized HF was seen in MTX initiators. #Abst1993 #ACR20 @RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Dr Kaellmark reports on immunogenicity of adjuvant herpes zoster subunit vaccine in RA patients treated with JAKi. 40 RA patients and 20 controls. Satisfactory serological responses and tolerability seen. @rheumnow #ACR20 Abstr#1997 https://t.co/UlDe4NllU0
Richard Conway RichardPAConway ( View Tweet)
Dr. N Nikolov #FDA reviews role for rheum meds in #COVID19 and outlines guidance for trial design for CV19 therapeutics #ACR20 @rheumnow https://t.co/0oPvBN5mgF
k dao KDAO2011 ( View Tweet)
Study out of China, #ABS1892 shows that patient reported outcomes using self assessments are important in AS T2T and decreasing flare rates #ACR20 @RheumNow. https://t.co/ebGtVUg8IV https://t.co/oXvGxQSjtn
Dr. Rachel Tate uptoTate ( View Tweet)
What are you doing at 12pm today on this #ACR20 Monday? I will be listening to @LCalabreseDO discuss the importance of #empathy in rheumatology @HealioRheum @RheumNow https://t.co/E1cH39z64p
Cassandra Calabrese CCalabreseDO ( View Tweet)
#ABS0597 All PR-COIN centers found telemed visits met provider needs & 18/19 centers believed telemed visits met pedi-rheum pt needs. Reasons for in-person visit included presence of active dz, worsening condition, & parent request/desire. #ACR20 @RheumNow https://t.co/yun6QCv4fX https://t.co/l9BrVMdJEa
Dr. Rachel Tate uptoTate ( View Tweet)
Abatacept in RA and ILD Patients: Dr Richard Conway (@RichardPAConway) #ACR20
https://t.co/e31VsnXFq5 https://t.co/sCrqLtXFFc
Links:
Dr. John Cush RheumNow ( View Tweet)
The 'triple M' irAEs (myositis/myocarditis/MG): one of the rheumatic irAEs where autoAb are freq pos
Nice systematic review:
any autoAb+ 61% tested
MG+ 59% tested
MSA+ in 27% tested (18/67, 11 had myositis alone)
@NilashaGhosh @lovetolearn27 @got_rheum #ACR20 ABST1574 @RheumNow https://t.co/utSj8yY0fd
David Liew drdavidliew ( View Tweet)
#FDA updates #ACR20 @rheumnow
labeling/warning changes:
belimumab- mortality removed
abatacept - angioedema added
baricitinib -hypersensitivity rxn added
gabapentin & pregabalin - respiratory depression added
k dao KDAO2011 ( View Tweet)
Do you routinely request for HLA-B27 in young patients w/ IBP? @RheumNow #ACR20
sheila RHEUMarampa ( View Tweet)
Deucravacitinib TYK2i for PsA
Phase2b 16wk, Double-blind, Placebo, RCT
⬆️ACR20/50/70 response vs. PBO
⬆️HAQ-DI response, enthesitis resolution, MDA vs. PBO
*⃣No serious AE
@RheumNow #ACR20 Abs#L03 #ACRbest https://t.co/9Klu2aeEj2
Robert B Chao, MD doctorRBC ( View Tweet)
When you give IA steroids for knee OA how long do you tell pts it will work for @RheumNow #ACR20 @CRASCRRheum abstr#1650
Janet Pope Janetbirdope ( View Tweet)
Plenty of great #telemedicine posters in "Measures & Measurement of Healthcare Quality" session! Abs#1584 reports telemedicine improves access to #rheumatology clinics & adherence, eg in those prev without adequate transport provision. #ACR20 @RheumNow
https://t.co/KwVxqcqu7n
Mrinalini Dey DrMiniDey ( View Tweet)
@uptoTate @RheumNow Agree. MD global is Often SJC taking into consideration activity severity and location of joints. Ex SJC of two ankles or knees is higher MD global than 2 MCPs. All N of SJC are not =. @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Using a panel of urinary prtns, data from this study show transferrin, AGP1, ceruloplasmin, MCP1 & sVCAM1 are sig. ⬆in active LN pts.
More studies req'd for confirmation.
Utility in monitoring renal response to tx?
@RheumNow #ACR20 abs1796 https://t.co/3Zicpz3uDd
sheila RHEUMarampa ( View Tweet)
