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Genicular Artery Embolization to Treat Osteoarthritis Knee Pain

d Jack Cush, MD

A study from the Journal of Vascular and Interventional Radiology has shown that  knee pain secondary to osteoarthritis (OA) may be effectively treated by selective vascular interruption (embolization) showing efficacy and safety in a small pilot trial. 

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ACR 2018 - Day 3 Report

d RheumNow

Highlights from Tuesday, day 3 of the ACR Annual meeting in Chicago, included the PEXIVAS Study, ACR Reproductive Health Draft Guidelines, and a Proof of concept study

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2019 Rheumatology Year in Review

d Jack Cush, MD

2019 was a year marked by major advances, hallmark research, and big news items affecting rheumatology.   Herein you will find our top 10 list, formulated by what I think rheumatologists should know and what will likely change their standards and practice in 2020 and beyond. 

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ACR-Arthritis Foundation Treatment Guidelines for Osteoarthritis

d Jack Cush, MD

Today, the American College of Rheumatology (ACR), in partnership with the Arthritis Foundation (AF), released the 2019 ACR/AF Guideline for the Management of Osteoarthritis of the Hand, Hip and Knee.

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Dr. Heidi Jacobi #UTSW lecturing on PSS skin disease Tx algorithm published in A&R. CTX has clearly dropped off https://t.co/l4fj8UzrtU
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Dr. Heidi Jacobi #UTSW lecturing on PSS. Other options for refractory dz include IVIG, RTX, TCZ, ABA and uVA1 therapy https://t.co/sn2sqXTFSN
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Study of 1054 adults with septic bone, joint, prosthetic infections shows that 6 weeks of oral antibiotic therapy cost less and was noninferior to IV antibiotic therapy (success rate ~85% at 1 year) while being >20% cheaper https://t.co/MYNxAWT1GT

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Dr. Heidi Jacobi #UTSW MMF maybe an alternative to MTX, but only has observational evidence https://t.co/6yzFCdgE6S
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Dr. Heidi Jacobi #UTSW shoes data that MTX works in SSc https://t.co/CzOmeg2ant
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Dr. Heidi Jacobi #UTSW says limited SSc has slowly progressive skin thickening of the distal extremities but also the face and neck.

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Dr. Heidi Jacobi #UTSW says the telangiectasias of CREST are usually a late, not early, finding

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Dr. Heidi Jacobi #UTSW says Raynauds, puffy digits and a +ANA should raise suspicion of systemic sclerosis. Also Carol tunnel syndrome may be a presenting feature

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Dr. Heidi Jacobi #UTSW lecturing on scleromyxedema often with "pebble like" lesions that during it from scleroderma https://t.co/5odVXrglyT
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#UTSW Rheumatology grand rounds with Dr Heidi Jacobi . Serologic and lab findings in patients with MOPHEA https://t.co/d619QnYrZ9
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Toscana is an arbovirus transmitted by sand flies in the Mediterranean. May fever, neuroinvasive infections & is an important cause of meningitis and encephalitis. May also cause Guillain-Barré, myositis, fasciitis, polymyeloradiculopathy, deafness, https://t.co/9X4OwAqRF9

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Misuse and abuse of Gabapentin in US? Between 2003-2016 there were 260 million gabapentinoid visits. Annual use nearly quadrupled from 2003 to 2016 (mostly PCPs 46%). Nearly half w/ concurrent opioids (32.9%) or benzodiazepines (15.3%). https://t.co/Wnja1mkDQo

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Systematic literature of biologic Rx of dactylitis & enthesitis in Psoriatic arthritis. 18 trials, 6981 patients showed that TNF inhib & ustekinumab, secukinumab, ixekizumab were 2-3 fold significantly better than PBO at resolution of dactylitis by Wk 24. https://t.co/HlQcw5cXsN

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301 fibromyalgia #FM pts randomized to receive active‐TENS or placebo‐TENS or no‐TENS to use at home 2h/day for 4 wks. Active TENS had greater reduction in pain & fatigue vs placeboAND better global improvement (70% vs. 31%, p<0.0001) https://t.co/AH84DxlTo3

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CORRONA registry 880 RA pts developed a solid cancer. 42% taking bDMARD/tsDMARD; 5% switched biologics w/in 36 mos & 10% started a new biologic- w/ most changing to a TNFi (53%). ACR guidelines say to Rx regardless of solid tumor https://t.co/pPgnYNdT7Q

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high-dose trivalent inactivated influenza vaccine (HD-TIV) was studied in 696 RA patients compared to standard-dose quadrivalent flu vaccine - Seroconversion was 3 fold higher w/ HD-TIV, no differences in side effects and no increase in RA flares https://t.co/1JBs95vGSA

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