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QD Clinic - "Doc, When Can I Stop?"

d Jack Cush, MD

QD Clinic - Lessons from the clinic. In this video: Patients stable on a biologic need guidance on when, and if, they can stop their biologic.

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Low Risk of Inflammatory Arthritis in Hidradenitis Suppurativa Patients

d Jack Cush, MD

JAMA Dermatology reports that after the onset and diagnosis of hidradenitis suppurativa (HS), such patients have a higher risk of certain forms inflammatory arthritis.

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QD Clinic - Hepatitis B and Biologics

d Jack Cush, MD

QD Clinic - Lessons from the clinic
Active HBV infection (HGsAg+) on anti-viral therapy but needs a biologic - what should you use?

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QD Clinic - "I Don't Know Why I'm Here" Consult

d Jack Cush, MD

QD Clinic - Lessons from the clinic
The Consult that shows up without a cause - and what to do?

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Biosimilars for Rheum Disease: Failure to Launch

d RheumNow

The availability of biologic biosimilars has thus far had negligible impact on prescribing practices in the United States, in stark contrast to what has been observed in some European countries, researchers reported.

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QD Clinic - Dealing with Non-adherence

d Jack Cush, MD

QD Clinic - Lessons from the clinic. Today’s clinic topic: Dealing with Non-Adherence in the Clinic.

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#UTSW Dr Lauren Nassi on JIA - enthesitis related arthropathy or ERA. 80% are B27+. May develop AS or SpA much later. They respond very well to TNF inhibitors

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#UTSW Dr Lauren Nassi on JIA - long term outcomes in Oligoarticular jia is not so benign. Half go on to polyarticular disease https://t.co/eRv52dtyZY
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#UTSW Dr Lauren Nassi on JIA- red flags with Oligoarticular JIA Painful joint Hip involvement High acute phase reactants

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#UTSW Rheum GR Rounds Dr Lauren Nassi on JIA - JIA accounts for 50-70% of all cases in a pediatric rheum clinic

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#MLK - "We may have all come on different ships; but we’re in the same boat now” Martin Luther King, Jr.

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#MLK - “We will remember not the words of our enemies, but the silence of our friends.” Martin Luther King, Jr.

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IL-37 may be a target for psoriasis. IL-37 is downregulated in lesional skin & IL-37 serum levels correlate with psoriasis severity. IL-37 is an anti-inflammatory & immunosuppressive cytokine from IL-1 family. Tofacitinib may increase IL-37 in psoriasis https://t.co/jPaGlcDFV2

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Population based study of ~72K chinese people shows that the DASH diet was assoc with significantly (30%) lower risk of hyperuricemia - more pronounced among older people (≥50 y), women and physically inactive (<0.01 for all). #Gout https://t.co/Ns1KzD5PfM

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Plasmapheresis Indications : TTP, HUS, Cryoglobulinemia, Hyperviscosity, Myasthenia gravis, Goodpastures, Catastrophic APL Syn, Chr inflamm demyelinating polyneuropathy, Removal of drugs/toxins, Alveolar hemorrhage, ANCA vasculitis (questionable) https://t.co/Prw62LB6WH

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#MLK - “If I cannot do great things, I can do small things in a great way.” Martin Luther King Jr.

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Hydroxychloroquine in RA metanalysis shows clinical efficacy of HCQ was similar to or lower than MTX or SSZ monotherapy. When HCQ combined with other DMARDs it increased the clinical efficacy. There is a paucity of data on HCQ structural (Xray) benefits https://t.co/Q5ukHrjybJ

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A of TB risk with TNF inhib - Risks by country: - Worldwide - 9.62 cases/1000 pts exposed - Asia, 13.47 /1000 - S America 11.75 /1000 - Europe, 6.28 /1000 patients - North America 4.34 /1000 (low risk (USA, EU) and high risk countries (Asia, S.Amer). https://t.co/MNtnjbEuMS

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Anti-transcription intermediary factor 1 (TIF1)-γ autoantibodies are linked with cancer-associated Dermatomyositis in adults https://t.co/DeBoDdEbV1

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#MLK - “The ultimate measure of a man is not where he stands in moments of comfort and convenience, but where he stands at times of challenge and controversy.” - Martin Luther King, Jr.

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