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“The artificial silos of medical subspecialties & departments ultimately needs to break down, and we should consider a new structure of medical care focused on disease mechanisms rather than clinging to our traditional organ-based thinking,” —Dr. Gravallese. #ACR20 @RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)

Tony Fauci is a hero, so thank you @ACRheum for bringing him (back) to #ACR20.
Today we get to *listen to Fauci*
#LTF @RheumNow https://t.co/VP28jXPxim
David Liew drdavidliew ( View Tweet)

TMA and SLE by Dr Levy @SickKidsNews
👉TMA triad - microangiopathic hemolytic anemia, thrombocytopenia, impaired renal function
👉TTP pentad - fever, thrombocytopenia, hemolytic anemia, renal impairment, neurologic involvement
#ACR20 #ACRambassador https://t.co/xnO1JkhSFT
Herman Tam DrPedsRheum ( View Tweet)

#Covid19 #vaccine candidates
Presented by Dr Anthony Fauci at #ACR20 Special Lecture
🗨️5/6 are in Phase III trials
🗨️Cautiously optimistic for a #CovidVaccine by the end of the year https://t.co/fuCumWmSk9
Dr Ai Lyn Tan DrAiLynTan ( View Tweet)

Feasibility of 18F-fluorodeoxyglucose Positron Emission Tomography to Monitor the Effect of Tocilizumab on Vascular Inflammation in Giant Cell Arteritis: A Prospective Observational Cohort Study https://t.co/Z91MhXJ5HK #gca #tocilizumab #pet what about the radiation?
Peter Nash drpnash ( View Tweet)

Autoimmune Disease Outcomes of Women with Breast Implants: A Population-Based Study https://t.co/Z6R8zRezfN #breastimplants #IMID an old chestnut
Peter Nash drpnash ( View Tweet)

The Use of Tocilizumab and Tofacitinib in Patients with Resolved Hepatitis B Infection: A Case Series https://t.co/2OBy0lxd6b #hepb #tocilizumab #tofacitinib no reactivation in resolved infection
Peter Nash drpnash ( View Tweet)

This is referring to Dr Dan Kastner https://t.co/3yQIUCcnAu
Dr. John Cush RheumNow ( View Tweet)

@RichardPAConway @DrDDRheum @DrErickZamora1 @hoffmann_vold @RheumNow YES! Why? 'Normal' echo in 1/3 of patients with early PAH. Screening# Diagnosis. Below is data where echo and RHC was done at the same time. in those with eRVSP < 36, 36% had RHC- derived PAH. https://t.co/W2YiyZnwwV
Dr. Dinesh Khanna sclerodermaUM ( View Tweet)

@DrDDRheum @DrErickZamora1 @hoffmann_vold If you have a normal HRCT and echo does a PFT at same time point add anything? Issues with getting PFTs in covid times #ACR20 @rheumnow @sclerodermaUM
Richard Conway RichardPAConway ( View Tweet)

This single slide tries to summarise all major phase3 clinical trials in Psoriatic Arthritis 💪
Take your time. The top half looks at joint efficacy. The bottom half for skin efficacy.
#ACR20 https://t.co/FXhJunXNKt
Dr Irwin Lim _connectedcare ( View Tweet)

Reducing Immunogenicity of Pegloticase (RECIPE) w/ concomitant use of MMF in pts w/ refractory gout is a phase II double blind RCT that shows sustained serum urate lowering effect in addition to decrease in monthly rate of flares. #ACRbest #Abst0952 @RheumNow Practice changing? https://t.co/Z7GwCXZftE
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)

AR882, a Potent and Selective Uricosuric Agent, Significantly Reduced Serum Urate Levels Following Multiple Ascending Once-Daily Doses in Healthy Subject Volunteers https://t.co/fRB2zuKl5J #gout #uricosuric a novel uricosuric agent
Peter Nash drpnash ( View Tweet)

Liraglutide as a Potential Intra-Articular Treatment for Cartilage Regeneration in Osteoarthritis: In Vitro and In Vivo Studies Supporting a Pro-Chondrogenic Effect https://t.co/T9IqF7E00Z #OA #DMOAD a potential DMOAD in mice
Peter Nash drpnash ( View Tweet)

Next up! #Autoinflammatory diseases: mechanisms and management. First: CRMO & SAPHO with Dr. Polly Ferguson
Highlights:
📍The *many* names of CRMO/CNO
📍Clinical features
📍Rx options (NSAIDs, bisphosphonates, TNFi)
📍Role of innate immunity in etiology
#ACRambassador https://t.co/qP3IySJKGC
Danny Soulsby dsoulsMD ( View Tweet)

Genotype analysis define new illnesses such as VEXAS.
”Somatic mutation may account for a significant fraction of adult-onset inflammatory disease” says Dr. Dan Castner.
Science enthusiasm at 3S038. Autoinflammatory Diseases.
@petercgrayson #ACR20 <TK https://t.co/gyTxF8NWtO
ARD & RMD Open ARD_BMJ ( View Tweet)

Based on RECIPE, how many of you will use MMF concomitantly with start of pegloticase in treating refractory gout patients? #ACR20 @RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)

@drdavidliew @VasculitisUMCG @RheumNow Dear David, thanks for your interest in our abstract #ACR20. This is based on some intriguing findings found in our previous observational study https://t.co/HKm53j2xou Still a work in progress but the potential adjunctive anti-inflammatory effect of ARBs seems attractive.
Marco A Alba, MD, PhD MA_ALBA_vascul ( View Tweet)

Dr. Anthony Fauci at #ACR20 -
“We are cautiously optimistic that we will have a safe and effective vaccine at the end of this calendar year and may be able to deploy in individuals with a high risk beginning in early 2021.”
@RheumNow
Robert B Chao, MD doctorRBC ( View Tweet)

Etanercept monotherapy significantly more effective than Methotrexate monotherapy in maintaining remission in RA patients on combination therapy. Data from the SEAM-RA study @RheumNow #ACR20 Abstr#0939 #ACRbest
Dr. Antoni Chan synovialjoints ( View Tweet)