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Abstr#2729: 303 pts randomized. More pts achieved ASAS40 at Wk 16: IXE Q2W (40%), IXE Q4W (35%) vs PBO (19%, p< 0.01) and at Wk 52: IXE Q2W (31%), IXE Q4W (30%) vs PBO (13%, p< 0.01). Blocking IL-17A is a potential treatment option for patients with nr-axSpA. #ACR19 @RheumNow
Maeve Gamble MaeveGamble ( View Tweet)
Fantastic view of how specific defects in the immune system lead to various clinical presentations and laboratory abnormalities. Dr. Mahta Mortezavi #ACR19 @RheumNow https://t.co/ht7VBhDdpR
Jonathan Hausmann MD hausmannMD ( View Tweet)
Drs. Davila and Solow say “No good data to suggest that biologic DMARDs contribute to progression of MGUS so okay to treat as you normally would.” #ACR19 @RheumNow https://t.co/5r2W4q1t5c
Dr. Rachel Tate uptoTate ( View Tweet)
While immunoglobulin replacement for patients with CVID prevents infections, it does not correct any of the autoimmune features....keeping rheumatologists busy! Dr. Mahta Mortezavi #ACR19 @RheumNow
Jonathan Hausmann MD hausmannMD ( View Tweet)
#acr19 @RheumNow
Dr West’s Pearls:
- at 40x magnification of synovial fluid, 1 WBC per hpf = 500 WBC/ uL (hence, 5 WBCs seen= 2500 WBC/uL which means the pt has an inflammatory fluid - you don’t have to wait for the lab results!) https://t.co/nChSnFq5NL
k dao KDAO2011 ( View Tweet)
The updated ACR/NPF treatment recommendations for PsA were discussed by Dr. Mease and Dr. E. Husni at #ACR19. Will you start with a TNFi, as per these recommendations, over other medications for your tx naive patients? @RheumNow
Dr. Rachel Tate uptoTate ( View Tweet)
Nice work showing PROs correlate with high disease activity in pts w/checkpoint inhibitor-related inflammatory arthritis abstr#2151 @cappelliMD @LCalabreseDO @RheumNow #ACR19 #cleclinicrheum https://t.co/Yi8LhNhA0v
Cassandra Calabrese CCalabreseDO ( View Tweet)
500 patients with CVID
-94% had infections
-30% had autoimmunity
-30% had chronic lung disease
-10% had granulomatous disease
-Dr. Mahta Mortezavi
Need I convince you any further to consider CVID when evaluating your patients with rheumatic disease?
#ACR19 @RheumNow
Jonathan Hausmann MD hausmannMD ( View Tweet)
#ACR19 poll: Do you use Prednisone to manage symptoms of hand osteoarthritis? @RheumNow
Dr. Paul Sufka psufka ( View Tweet)
Nice job @didemsayginmd ! Abstr#2144 single center rheumatic irAE experience - 50% required ICI interruption! 20% needed DMARDs @RheumNow #ACR19 #cleclinicrheum https://t.co/dGaIaKzYFS
Cassandra Calabrese CCalabreseDO ( View Tweet)
@rheumnow #ACR19 ABS2594 prospective cohort study of 56 early cutaneous SSc pts found no association between ETAR &AT1R Abs positivity & vascular complications making ETAR &AT1R abs unlikely prognostic markers of Vasc complications #acrbest https://t.co/e9kNSFeBOx
Olga Petryna DrPetryna ( View Tweet)
Some immunodeficiencies present primarily with autoimmune or lymphoproliferative features…hence the need to consider immunodeficiency in patients with suspected rheumatic disease. Dr. Mahta Mortezavi #ACR19 @RheumNow
Jonathan Hausmann MD hausmannMD ( View Tweet)
@DBrandmanMD speaking at #ACR19 on NAFLD:
HOW MUCH WEIGHT LOSS to do you need to improve/reverse stages of #FattyLiver?
>3% for steatosis
>5% for NASH improvement
>7% for NASH resolution
>10% for cirrhosis reversal (only 10% of pts get there)
@RheumNow @ACRheum
Adam Kilian MD KilianMD ( View Tweet)
As recommended by @doctorswade's research, Dr. Mahta Mortezavi recommends checking baseline immunoglobulins prior to rituximab use. #ACR19 @RheumNow https://t.co/EMapSb0tTW
Jonathan Hausmann MD hausmannMD ( View Tweet)
@RheumNow 5T063 Immunodeficiency for the Rheumatologist: immune defects and corresponding clincial features https://t.co/iUvjP6hNdY
Olga Petryna DrPetryna ( View Tweet)
Gut microbiome-altering drugs like steroids, PPIs and antibiotics had negative effect on tumor response when given prior to checkpoint inhibitor therapy abstr#1811 @RheumNow @cappelliMD @LCalabreseDO #acr19 #cleclinicrheum
Cassandra Calabrese CCalabreseDO ( View Tweet)
Dr. Mease discusses the ACR/NPF recommendations for treatment naive PsA pts. This slide details starting with TNFi for patients. #ACRbest #ACR19 @RheumNow https://t.co/0GZ2RFPWjW
Dr. Rachel Tate uptoTate ( View Tweet)
Romo increased BMD across eGFR subgroups vs Pbo. Reduction in new vertebral fractures not affected by eGFR. https://t.co/HMkREcwoQj #ACR19 @RheumNow plenary#2730 #ACRbest https://t.co/9ojwhmmZxx
Dr. Rachel Tate uptoTate ( View Tweet)
Abstr# 2160: Myopenia is associated with risk of rotator cuff tearing in the elderly.
A great reminder to encourage exercise and building muscle mass to our patients. #ACR19 @RheumNow https://t.co/w5WrL6YcD7
Dr. Paul Sufka psufka ( View Tweet)
#ACR19 Poll: When treating PMR, how do you recognize when patients are having a relapse or flare while tapering steroids? @RheumNow
Dr. Paul Sufka psufka ( View Tweet)