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ICYMI: Allopurinol Safety in CKD Patients
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Jul 06, 2022

A study in the Annals of Internal Medicine reports chronic kidney disease (CKD) patients can be safely treated with allopurinol without an increased risk of mortality.

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#EULAR2022 has concluded but you can find all our coverage here https://t.co/s62OVJPQ86 https://t.co/QAvPQYCABj

Links:

https://bit.ly/3xBn2D5

Dr. John Cush RheumNow ( View Tweet)

Jun 18, 2022

Gout Undertreatment Persists Despite updated gout management guidelines from EULAR and BSR, treatment of gout is suboptimal with regard to the use of urate-lowering therapy (ULT) and normalizing serum uric acid (< 6.0 mg/dl) levels.https://t.co/qW7ZaXbnx3 https://t.co/ZBKIjuQp10

Links:

https://bit.ly/3NDMLBM

Dr. John Cush RheumNow ( View Tweet)

Jun 10, 2022

Gout Undertreatment Persists
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Jack Cush, MD

Jun 08, 2022

Despite updated gout management guidelines from European (EULAR) and British (BSR) societies, treatment of gout is suboptimal with regard to the use of urate-lowering therapy (ULT) and normalizing serum uric acid (< 6.0 mg/dl) levels.

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Topical therapies take centre stage Topical treatments have so often been the low level “sure you can try this” option. However there are exciting data that these approaches may become part of our main armamentarium. #EULAR2022 https://t.co/V9plk1vAEd https://t.co/fyNWWtconi

Links:

https://bit.ly/3mhg0y3

Dr. John Cush RheumNow ( View Tweet)

Jun 06, 2022

Topical therapies take centre stage
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Richard Conway, MBBChBAO, PhD

Jun 04, 2022

Topical treatments have so often been the low level “sure you can try this” option. However there are exciting data that these approaches may become part of our main armamentarium.

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Real World Data on Urate Lowering Therapy
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Eric Dein, MD

Jun 04, 2022

Urate lowering therapy (ULT) is the backbone therapy for long-term gout treatment and maintenance, but real-world gout management is often imperfect and suboptimal.

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#EULAR2022 POS0285 130K UK patients had incident gout bw 2004-2020 ⭐️Only 29% started on ULT w/in 12 mos ⭐️Target urate level only 14% in 2004, only to 17% in 2020 Updated EULAR guidelines in 2016: No statistical difference in ULT Rx or target attainment @Rheumnow

Eric Dein ericdeinmd ( View Tweet)

Jun 04, 2022

#EULAR2022 POS0282 Febuxostat vs allopurinol: CV risk population study ⭐️16% reduction in all-cause mortality among febuxostat users, mostly non-CV death reduction ⭐️CV safety non-inferior to allopurinol @Rheumnow https://t.co/1oDSioQWPT

Eric Dein ericdeinmd ( View Tweet)

Jun 04, 2022

#EULAR2022 POS0283: Do Rheums have Gout Stigma? ⭐️Stereotypes about pt related factors ⭐️Rheumatologists feel diet, exercise, wt loss more important in gout than RA, pharmacologic therapies less important than RA @Rheumnow

Eric Dein ericdeinmd ( View Tweet)

Jun 04, 2022

#EULAR2022 POS0280 Gout is associated with higher mortality in Women ⭐️Higher all cause and CV mortality RR 1.28 risk of mortality in pts without CHD, with gout compared to controls (No CHD or gout) @Rheumnow https://t.co/6o1EKSp2F8

Eric Dein ericdeinmd ( View Tweet)

Jun 04, 2022

So what diet to follow with autoimmunity in mind? So many, all with different instructions. Let’s concentrate on where they agree: yes to fruits & vegetables no to emulsifiers & processed foods #EULAR2022 @RheumNow https://t.co/I9abweQOyZ

David Liew drdavidliew ( View Tweet)

Jun 03, 2022

Hilarious debate #EULAR2022 between Christian Dejaco and Robert Landewe on whether telemedicine is the future of rheumatology. In amongst the trash talking, here are some highlights @RheumNow

David Liew drdavidliew ( View Tweet)

Jun 03, 2022

#EULAR2022 POS0278: Proof of concept US study: 💎CPP crystals do NOT generate posterior shadowing 💎MSU and hydroxyapatite did have shadowing, proportional to concentration of crystals @Rheumnow @MymaAlbaydaMD @USSONAR_Rh

Eric Dein ericdeinmd ( View Tweet)

Jun 03, 2022

EULAR 2022 – Day 2 Report
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Jack Cush, MD

Jun 02, 2022

A full day at EULAR with oral and poster presentations of abstracts in the morning and a plethora of scientific (review) sessions in the afternoon. The latter covering topics like sarcoidosis, Still’s disease, fibromyalgia, back pain, sarcopenia, APS, IgG4 and imaging in vasculitis.

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Dr Puja Khanna. Transdermal sodium bicarbonate for gout flare. WHAT!? It works as well! Double-blind RCT. All got colchicine also. Response rate 95% vs 79%. Resolution in 24 vs 72 hrs. Rescue meds 6% vs 20%. No adverse events! @RheumNow #EULAR2022 OP0170 https://t.co/INd4tMFVlV https://t.co/EyVjFLF72z

Links:

EULAR Abstract Archive

Richard Conway RichardPAConway ( View Tweet)

Jun 02, 2022

Farshad et al. 17% of admissions on long-term allopurinol had it held. Reasons - acute gout flare, renal impairment, gastrointestinal issues, cytopenia, drug interactions, NPO status, and always discontinued the medication. @RheumNow #EULAR2022 OP0169 https://t.co/ADOomiOrRi https://t.co/nxAAOMWsJB

Links:

EULAR Abstract Archive

Richard Conway RichardPAConway ( View Tweet)

Jun 02, 2022

Botson et al. 152 patient RCT. MTX combo with pegloticase (to decrease antidrug abs). 6-month response (sUA<6 mg/dL) 71% vs 39%. Infusion reactions 3% vs 31%. @RheumNow #EULAR2022 OP0171 https://t.co/N29kYT3xkR https://t.co/Z4dUMD4Tt3

Links:

EULAR Abstract Archive

Richard Conway RichardPAConway ( View Tweet)

Jun 01, 2022

Dr. Jack Cush reviews the news, regulatory updates and journal reports from the past week on https://t.co/V10S4oVFsv. This week gout worries, mortality risks, measuring anti-drug antibodies and a better way in lupus?https://t.co/iaMQZtzdLm https://t.co/Zu9VwKoCAc

Links:

http://RheumNow.com

Dr. John Cush RheumNow ( View Tweet)

May 28, 2022

Links:

https://bit.ly/3lOmOTJ

Dr. John Cush RheumNow ( View Tweet)

May 28, 2022

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