Should You Repeat the ENA Panel? Dr. Kathryn Dao ( @KDAO2011) discusses abstract 0725, presented at #ACR22 Convergence. Abstract 0725: Utility of Repeat Extractable Nuclear Antigen Antibody Testing- a Retrospective Audit https://t.co/6A2ksN6yC2 https://t.co/U62Ab7jj3d

• https://bit.ly/3O9wYMe

Strand et al PROs from SAPHYR (ping @EBRheum ) Significant improvement in SF-36 physical and mental, EQ-5D-3L. Numerical improvement in EQ VAS, FACIT-F, HAQ-DI, PtGA, and pain scores @RheumNow #ACR22 Abstr#2243 https://t.co/RffjBHkjIU https://t.co/0wbnmUhbWy

• Patient Reported Outcomes from a Randomized Phase 3 Trial of Sarilumab in Polym…

"A novel mode of action which has generated a degree of excitement" - Paul Emery PD-1 agonist - peresolimab in RA Good impact in b/tsDMARD refractory patients "Correction of an immune state" - we're shooting for homestasis Definitely a space to watch! ABSTL01 #ACR22 @RheumNow https://t.co/W2lWrBgNOT

McDermott @jeffsparks et al. Subpleural ILAs on CT in 16% RA vs 5% non-RA, OR 3.74. 10 year mortality 53% RA-ILA vs 23% RA non-ILA, 22% non-RA non-ILA. HR mortality 3.20 for RA-ILA vs RA non-ILA @RheumNow #ACR22 Abstr#2248 https://t.co/HZ3y8CANUl https://t.co/nfjFq2REEh

• Prevalence and Mortality of Interstitial Lung Abnormalities in Rheumatoid Arthr…

Figueroa Parra @zach_wallace_md @jeffsparks @AliDuarteMD RA patients have higher risk of severe COVID, especially those with ILD @RheumNow #ACR22 Abstr#2249 https://t.co/xUwStp451C https://t.co/N5A0oo1Kyk

• Impact of Interstitial Lung Disease on COVID-19 Severity Among Patients with Rh…

#ACR22 Abs 2144: JAK inhibition induced different gene profile in circulating immune cells w/prominent downregulation of pro-inflammatory pathways in CD4+naïve T cells AND a shift in their metabolic signaling towards a more quiescent state. @RheumNow https://t.co/qYmr6A3zvS

• JAK Inhibition Re-balances Gene Expression Profile of Circulating Immune Cells …

Dual Energy CT Study in 32 #gout pts on #allopurinol escalated over 2 yrs to achieve Uric acid <6 - tophus urate volumes and tophus soft tissue volumes reduced - chronic inflammatory soft tissue within the tophus is slower to respond than crystals @RheumNow #ACR22 abst#2203 https://t.co/dtHQqg9iFR

BD-2 novel, PsA-specific predictive biomarker of clinical arthritis response to SEC. Pts w/ high levels of BD-2 at baseline reach and sustain higher rates of clinical response after tx w/ SEC. Abs 2148 #ACR22 @RheumNow https://t.co/9ZJz2C0Pep https://t.co/5gf2O7B0c5

• Analysis of Serum Proteomics Data Identifies Beta-Defensin 2 as a Predictive Bi…

Abstr #2193 studies invasive fungal infxn in Autoimm/Rheum dx - PJP most common (41.5%) - Mortality highest among fungemia (48.7%) and invasive aspergillosis (38.3%) vs PJP (26.1%) - Older age, cirrhosis, high dose GC assoc w ↑ mortality @RheumNow #ACR22

Monday: ACR 2022 Daily Recap https://t.co/AKYrkLTPJe

• https://twitter.com/i/broadcasts/1ypJddyBqqgJW

We'll be going live with our #ACR22 daily recap at 5pm ET. Find us on Twitter, LinkedIn, Youtube and Facebook. https://t.co/hjAyOOynZM