David Liew drdavidliew
3 years 10 months ago
I was schooled for exams, testing fine motor function with a buttonhole: felt contrived.
Imagine an electrical glove for RA pts, doing functional assessment properly
Italian study: engineered glove data + HAQ correlates with DAS28
Consistent/scalable!
ABST0904 #ACR22 @RheumNow https://t.co/4ZR0An5N9j
Richard Conway RichardPAConway
3 years 10 months ago
Martínez-López et al. Higher rates of elevated transaminases with DMARD in those who previously had abnormal transaminases with isoniazid. @RheumNow #ACR22 Abstr#0816 https://t.co/xiL6DPPcw3 https://t.co/jjxRoEr8iM
Richard Conway RichardPAConway
3 years 10 months ago
Khidir et al. Lower educational level increases risk of progression of clinical suspect arthralgia to inflammatory arthritis. HR 2.35 and 5.72 in 2 cohorts. not explained by smoking, BMI or a delay in seeking medical care @RheumNow #ACR22 Abstr#0704 https://t.co/B4bm2Ihapx https://t.co/Veks0WpHLR
Eric Dein ericdeinmd
3 years 10 months ago
Ab1042 #ACR22 Ixekizumab Long-term Safety
A Deodhar: Pooled 25 studies for PsO, PsA, AS
5.4 pooled AE per 100-patient/year
0.5 IBD per 100-PY
1.3 Oral candidiasis per 100-PY
Re-assuring safety numbers. Deodhar: "These are numbers to use in clinical practice"
@RheumNow
Data presented at ACR22 shows that cycling through TNFi in axSpA patients with primary lack of efficacy with first line TNFi has limited additional benefit in controlling disease.
Richard Conway RichardPAConway
3 years 10 months ago
Hamroun et al. Unfavourable pregnancy outcomes associated age, nulliparity, steroids in RA. Can only modulate the final one! @RheumNow #ACR22 Abstr#0955 https://t.co/Vob1GeMN25 https://t.co/CsVshIzp8a
Aurelie Najm AurelieRheumo
3 years 10 months ago
de Hooge & al: parameters assoc w/ risk of developing syndesmophytes at 2 yrs in PsA:
Radiographic SI according to mNY = 30x higher risk
If Rx SI + CRP>6 = 100% risk devlpmt syndesmophytes @ 2 yrs.
https://t.co/CR0LymrQdr
Abs#1014 #ACR22 @Rheumnow
#ACRBest https://t.co/TLWYCJ0eYi
Richard Conway RichardPAConway
3 years 10 months ago
Rouhi @Janetbirdope et al RS3PE post checkpoint inhibitor. 11 cases. Can flare after checkpoint inhibitor reintroduction and occur following treatment. @RheumNow #ACR22 Abstr#0758 https://t.co/KCzdJvD0da https://t.co/WQ4eB2hz1k
Aurelie Najm AurelieRheumo
3 years 10 months ago
Giblo et al, 1000+ pop-based cohort RA:
Cumulative incidence of depression =
Increase in cumulative incidence of anxiety 2005–14 vs. earlier decades
Despite improvements in RA ttmts. Maybe time we address these separately?
https://t.co/Z3FUgSETKW
Abs#0889 #ACR22 @Rheumnow https://t.co/Rn2ru80021
Richard Conway RichardPAConway
3 years 10 months ago
Kang @karen_kc123 et al ≥ 20 pack-years cigarette smoking associated with higher risk of incident PMR in women (HR 1.46). Every 10 pack-years associated 9% increase in risk @RheumNow #ACR22 Abstr#0698 https://t.co/t51fKFs7iJ https://t.co/IS9XC9DXl8
Richard Conway RichardPAConway
3 years 10 months ago
Maguire @Sineadm15 @rheum_covid (and me!) obstetric outcomes in RMD and COVID-19. Unvaccinated higher freq pre-term birth. Regardless of vaccine status, the women themselves did well, rarely needing pharmacotherapy @RheumNow #ACR22 Abstr#0950 #ACRbest https://t.co/GLMAAvbC4a https://t.co/kpXZbRSoMo
Aurelie Najm AurelieRheumo
3 years 10 months ago
DIPSA: RCT in PsA pts w/ BMI > 25 Mediterranean diet vs. DASH-low caloric diet vs. SoC
BL: 72% obese, 42% dyslipidemia, 38% HBP, MetS 47%
Looking forward to seeing the results of this dietary intervention, MetS is high in PsA!
https://t.co/29Aq0TLANO
Abs#1007 #ACR22 @Rheumnow https://t.co/MoVYnQV6xR
Eric Dein ericdeinmd
3 years 10 months ago
Ab0411 #ACR22 Bimekizumab in AS
P3 24 wk PBO control study BE-MOBILE 2
221 BKZ, 111 PBO
Wk 16 ASAS40: BKZ 45%, 22% PBO p<0.001
Efficacy in both TNF naive and TNF failure pts
Wk 24: 1/2 pts has ASDAS<2.1
Nasopharyngitis (6%), diarrhea (4%), h/a (3.6%) 👅candidiasis (3%)
@Rheumnow https://t.co/R1ieW0FB6m
Richard Conway RichardPAConway
3 years 10 months ago
Mathew et al. Combination biologics from MarketScan. Combination less likely to have ER visit in 180 days 17% vs 23% @RheumNow #ACR22 Abstr#0768 https://t.co/Y880qDXMow https://t.co/gOH2Zlt6UV
Aurelie Najm AurelieRheumo
3 years 10 months ago
CASIPSA study: retro CT SIJ analysis 48 PsA & age/sex matched ctrls.
JSN, erosion, sclerosis in 1/3 pts w/ peripheral & 1/3 pts w/ axial disease.
PsA > erosions, no diff in other parameters: lack of power or true absence of diff?
https://t.co/CR0LymrinT
Abs#1012 #ACR22 @Rheumnow https://t.co/akYYqbIFNx

