Female physicians were more likely to be called by their first names in electronic medical record (EMR) patient portal messaging, researchers found.
Dr. John Cush RheumNow
4 years 1 month ago
8 pts w/ Refractory Skin Dermatomyositis Rx w/ open label APREMILAST, @ 3 mos 7/8 pts responded w/ drop in CDASI (-12.9 pts; P < .001). Skin Bx showed downregulation of multiple inflamm pathways (STAT1/3, IL-4), IL-6, IL-12, IL-23, IFNγ & TNFα) https://t.co/V6RZdg9y6V https://t.co/ppSUzlAP4D
Dr. John Cush RheumNow
4 years 1 month ago
PhRMA estimates that 90% of US healthcare spending is on chronic conditions. Currently there are ~800 drugs in development for chronic Dz - with 70 drugs in Ph1-3 development for arthritis: OA, RA, PsA, Gout (>1/3 in Phase 3) https://t.co/cozMhQI3UH https://t.co/uZe6L2ph87
Hamilton, ON (Oct. 4, 2022) – Patients can recover from orthopedic surgery just as well without using opioid-based painkillers, says a McMaster University and Hamilton Health Sciences (HHS) study published by the Journal of the American Medical Association (JAMA).
Dr. John Cush RheumNow
4 years 1 month ago
The University Of Pennsylvania has recv a $50 Million Gift (from Stewart & Judy Colton) to further develop the Autoimmune Disease Research program at Penn’s Colton Center for Autoimmunity. 6.4% of women and 2.7% of men have autoimmune disease https://t.co/gMdoiZFTdB https://t.co/BZHn1mSmHU
Dr. John Cush RheumNow
4 years 1 month ago
A retrospectively cohort study of 147 r-AxSpA patients looked at secukinumab retention, which was 55% at 12 mos. Obesity was assoc w/ a lower rate of SEC D/C (29% v 50%, p = 0.013). Yet multiple TNFi had higher rate of SEC D/C [HR 1.99] https://t.co/OZIZoTROZS https://t.co/M99ANDGzv9
Juvenile idiopathic arthritis (JIA) may start in adolescence and extend into adulthood. This report of the Nordic experience shows that both pediatric and adulty rheumatologists need to develop "transition" practices; without such an approach considerable gaps in healthcare will befall these JIA patients.
Dr. John Cush RheumNow
4 years 1 month ago
JAMA Oncology reports in 1st 10 mos of pandemic, 16,500 cancer pts died from COVID+complications; w/ signific more COVID-19-related cancer deaths than cancer deaths w/o COVID-19 in blood CA(23% v 10%) & prostate CA (12% v. 5.5%) https://t.co/036VU8H1vx https://t.co/tWh8749pTx
Dr. John Cush RheumNow
4 years 1 month ago
Microbioime analyses of cancer patients suggests over abundance of fungi, expecially transcriptionally active Candida and is associated with gastrointestinal and lung cancers.
Candida DNA is also predictive of reduced survival in GI cancers https://t.co/YoMOvvskqz https://t.co/6hC6Y4YAc1
While it is known that smoking ups the risk of developing RA, its effect on outcomes in those with established rheumatoid arthritis (RA) is less known. A report from an early arthritis registry shows that current smoking increases disease activity and lowers health-related quality of life.
Dr. John Cush RheumNow
4 years 1 month ago
New look at fibrosis in scleroderma finds low levels of the antifibrotic protein, endostatin & Cathespin L. In vitro studies show a deficiency of Cathepsin L that should lead to its activation of antifibrotic endostatin - possibly a new Rx strategy for SSc https://t.co/qaLN0PVnLO https://t.co/TDK4sBZMV0
Dr. John Cush RheumNow
4 years 1 month ago
COVID-19 Arthropathy and Myalgia
An online survey of random COVID-19 infected persons shows that arthralgia and myalgia are common consequences to COVID-19 infection.
https://t.co/TbJvTRfsvk https://t.co/yuLN5p5ZAn
The California Lupus Surveillance Project has longitudinally followed included systemic lupus erythematosus (SLE) cases and shown that overall, the leading cause of death was cardiovascular disease (CVD), followed by rheumatic disease and hematologic/oncologic conditions.
Analysis of data from a Czech nationwide registry of psoriatic patients receiving biologic or targeted therapies (BIOREP) has shown a high success rate when switching between specific IL-17 inhibitors.
Dr. John Cush RheumNow
4 years 1 month ago
Dr. Alfonse Masi donates $1.2 Million to establish the Masi endowed chair in Medicine at the University of Illinois College of Medicine, Peoria. Dr. Masi is a giant clinician, researcher, epidemiologist in Rheum w/ > 220 Pubs & Yrs service to the ACR https://t.co/MbCFVZyNs1 https://t.co/LQ9D0ypA53

