Dr. P Crow #PhilipHenchLecture IFN signature can parallel or predict flares #ACR21 @rheumnow https://t.co/OskxDuKPDH

Abstr 0579 Kim & Colleagues examined predictors of Tx change among RA patients w/ TNFi as 1st line biologic agent - Females & GC use more likely to switch agent - Vitamin D use & hx of other immune-mediated diseases (eg. Psoriasis, IBD) less likely to switch #ACR21 @RheumNow https://t.co/FM5mSWmSNA

@zach_wallace_md on RTX vs CYC remission induction in AAV. Multivariable and propensity score matching. No difference in ESRD or mortality. Real world confirmation of RAVE. Abstr#954 #ACR21 @RheumNow https://t.co/oSauqV8JnD

Abst0944 #ACR21 #ACRBest @RheumNow microbiom evaluation of MZ twins discordant for PSO reveals Ruminococcus bromii species significantly reduced & two pathways related to tetrahydrofolate biosynthesis upregulated in PSO twins compared to their unaffected siblings (p< 0.05) https://t.co/67ao0l23sI

#ACR21 Clinical Pearl: Beware of low cholesterol! Systemic inflammation can lower cholesterol levels! High inflammation and low cholesterol may INCREASE, not decrease risk of CVD! This is the "lipid paradox" @Rheumnow https://t.co/dK7hD8zkVP

Soluble urinary ALCAM previously shown as potential biomarker for LN. Further study showing urinary ALCAM trended with changes in renal-SLEDAI and UPCr. #ACR21 Abst#3053 @RheumNow https://t.co/IqVJej7yda

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Abst 0947 #ACR21 @RheumNow KikGR x TNFDARE/+ mice study assessed contribution of gut-derived T cells to increased joint inflammation through production of pro-inflammatory cytokines like IL-17 and TNF. Photolabeled gut-trafficked T cells are observed in the Achilles enthesis

Important to discuss men with #lupus Nationwide claims study showed increased occurrence of multimorbidity in men with SLE compared to women with SLE #ACR21 @RheumNow @AliDuarteMD Abst#0579 #ACRBest https://t.co/ljflGU84Ro

No evidence to show increased risk of incident hypertension w/ TNFi use, after accounting for baseline & time-dependent confounding factors, in prospective AS cohort. Abs 0910 #ACR21 #RheumNow @RheumNow https://t.co/1SpQ51ftlK

• The Association of TNF Inhibitor Use with Incident Hypertension in Ankylosing S…

Ear dyspigmentation, scalp dyspigmentation and scarring alopecia found more frequently in Black DLE pts. Findings may help assist in dx and tx plans. Abs 0598 #ACR21 #RheumNow #ACRbest @RheumNow https://t.co/a1pxWHJ7b5

• Differences in Discoid Lupus Erythematosus Skin Lesion Distribution and Charact…

Does AAV induction choice (CYC v RTX) affect long-term outcomes (that might be missed in clinical trials)? Boston data done two ways: multivar analysis & trial emulation using PS CYC and RTX-based induction both perform equally well over many years👍 #ACR21 ABST0954 @RheumNow https://t.co/8BZRgKiQNB

Dr Strand presents HRQoL measures for avacopan from ADVOCATE trial. Better HRQoL outcomes with avacopan. Great to have PRO data. Abstr#0955 #ACR21 @RheumNow https://t.co/9qBAHETX7s

French, real-world axSpA cohort analysis shows SEC and TNFi retention rates similar. What do you see in your practice? Abs 0911 #ACR21 #RheumNow @RheumNow https://t.co/vu3zUwfktl https://t.co/v6DLjWJMn4

• Drug Retention of Tumor Necrosis Factors and IL-17 Inhibitors in Axial Spondylo…