An erosive hand osteoarthritis (EOA) study from the Osteoarthritis Initiative shows that EOA is more common in older women and is strongly linked to further progressive, articular structural damage.
This was a longitudinal cohort study of 3,365 individuals without prevalent erosive hand OA at baseline.
Ogdie and colleagues have retrospectively analyzed a longitudinal cohort of psoriatic arthritis (PsA) patients, showing that only two-thirds of PsA are diagnosed by rheumatologists, PCPs and dermatologists, with significant differences in what preemptive symptoms were noted by different subspecialties.
Dr. John Cush RheumNow
4 years 11 months ago
We are at that time of year when rheumatology fellowship programs across the nation are exploring potential candidates to train. We share tips for both the interviewer and candidates on the blog today.
https://t.co/eWQs9CwqSm https://t.co/iHeuQpsoQx
Dr. John Cush RheumNow
4 years 11 months ago
Lessebo effect: 31 RCT comparing Biologic originator to a biosimilar or to PBO: Lessebo effx =better responses in Biosimilar vs PBO (ACR20=70%) than w/ originator vs PBO (ACR20=59%). ? due to PBO effx in active comparator, nocebo in PBO trials https://t.co/kvANomTHrb
Dr. John Cush RheumNow
4 years 11 months ago
Beliefs translate to effects - ‘it will work’ (Placebo), ‘it will hurt’ (Nocebo); but now a "Lessebo" effect; neither benefit nor harm; instead a lower effect based on comparator. TNFi vs PBO has smaller effx (sup trial) than Biosimilar vs PBO (equiv) https://t.co/onyIkILqT9
Dr. John Cush RheumNow
4 years 11 months ago
Drug Safety Risk Communication- The 800 lb Gorilla Approach
https://t.co/6iSJjvlFF8 https://t.co/mPeJfWi1hY
Dr. John Cush RheumNow
4 years 11 months ago
ASK CUSH ANYTHING!
Rheums: Have a question for Dr. Cush? Record it here and we may feature it on an upcoming podcast. #RheumNow
https://t.co/wzNmOzH4VE https://t.co/KzPzWpSoW1
Dr. John Cush RheumNow
4 years 11 months ago
Metabolic syndrome (MetS) is associated with radiographic & nodal hand OA (HOA). 896 MetS positive & 1613 w/o MetS assessed w/ propensity matching. MetS had more xray HOA ((OR 1.32), PIPs (OR 1.52), DIPs (1.38), hand pain (1.25)https://t.co/aNEV5b6Tmv
Dr. John Cush RheumNow
4 years 11 months ago
Malnutrition and Quality of Life in Elderly RA Patients
https://t.co/4hEFTSaCga https://t.co/OPK3ThWqst
Dr. John Cush RheumNow
4 years 11 months ago
Patients with longstanding systemic lupus erythematosus (SLE) who were considered frail were more likely to accrue disease damage over time, a secondary analysis of data from a Chicago lupus cohort found.
Read more on #RheumNow
https://t.co/jQt5mFrMtS https://t.co/HljgqdKZtH
Dr. John Cush RheumNow
4 years 11 months ago
The AAOS has published their Clinical Practice Guideline for Management of Osteoarthritis of the Knee (Non-Arthroplasty); updating 19 of the 29 evidence-based recommendations and focuses on nonsurgical treatmentss to provide pain and patient function.
https://t.co/faLi0X840d https://t.co/8iZkNEFkRy
Rheumatoid arthritis (RA) imparts a significant disabilty and quality of life (QoL) limitations worsened by aging, but also by malnutrition.
Patients with longstanding systemic lupus erythematosus (SLE) who were considered frail were more likely to accrue disease damage over time, a secondary analysis of data from a Chicago lupus cohort found.
Dr. John Cush RheumNow
4 years 11 months ago
Study of 380 nonintubated severe COVID-19 pneumonia patients showed that those with the highest tertiles of FERRITIN (1322-13 ,418) showed significant reduction in mortality (HR, 0.16; 0.06-0.45) if given methylprednisolone [120-240] mg https://t.co/Jr1aWlPpOk
Dr. John Cush RheumNow
4 years 11 months ago
Secukinumab (IL-17 inhibitors) can be safely used in HIV spondyloarthritis patients. https://t.co/hpCRJkR9w7
