Dr. John Cush RheumNow
5 years ago
SENSCIS trial compared 1 yr of nintedanib (NIN) vs placebo in 576 SSc-ILD pts. NIN was more effective (less FVC decline) in 1) α-topoisomerase Ab neg (57.2 vs 30 ATA+), 2) mRSS ≥18 (88.7 vs 26 mRSS<18), & 3) diffuse (57 vs local 25) SSc pts https://t.co/cLuTBDeJD6
Dr. John Cush RheumNow
5 years ago
Alendronate may protect against type 2 Diabetes. Data from National Danish Patient Registry, presented at the EASD meeting compared 160k T2DM & 500k controls, T2DM following alendronate adjusted OR=0.64; 0.62-0.66); >8yrs OR=0.47 https://t.co/RYEZodUZtv
Today, CDC issued an urgent health advisory to increase COVID-19 vaccination among people who are pregnant, recently pregnant (including those who are lactating), who are trying to become pregnant now, or who might become pregnant in the future to prevent serious illness, deaths, and adverse pregnancy outcomes.
Dr. John Cush RheumNow
5 years ago
TONIGHT! the ACR is holding a " Just Diagnosed: Now What? Patient Webinar" - this will feature Academy-nominated screenwriter & patient Emily Gordon ("The Big Sick") with Rheumatologist Stuart Kassan, MD, register here: https://t.co/TOCgOuV0Ng
Dr. John Cush RheumNow
5 years ago
Analysis of 508 #RA pts (over 10 yrs) in the BeST study shows joint swelling at baseline resulted in half w/ re-swelling later and significantly increased risk of same joint swelling during follow-up (OR 2.37, 95% CI 2.30 to 2.43, p<0.001) https://t.co/a7zH4YRAkq
Dr. John Cush RheumNow
5 years ago
PROCEED study of 300 pts with chronic, DXA proven bone loss in half (osteopenia in 39% and osteoporosis in 17%) with higher fracture rates. Such pts should undergo screening for osteoporosis. https://t.co/7fgeAk85vu
Discussions on drug safety can be as treacherous as quicksand for the patient and physician. What the physician knows and what the patient perceives may not be in sync.
Dr. John Cush RheumNow
5 years ago
Are you an Expert in Still's disease, Periodic Fevers, FMF or Autoinflammatory Dz? I will add you to our expert referral listing on https://t.co/LYd3dtU295. DM me to get on the list! https://t.co/lt8YMPOpK2 https://t.co/QxXHMvayTG
Dr. John Cush RheumNow
5 years ago
U.S. Preventive Services Task Force (USPSTF) reaffirmed its recommendations that pregnant women at a high risk of preeclampsia should take a daily aspirin regimen at the end of the first trimester https://t.co/DiV7p6g8vL
Dr. John Cush RheumNow
5 years ago
Finnish Pop study 939 #RA pts shows highest healthcare costs linked to high Dz activity & comorbidity. Clusters: C1) young w/ low costs & activity, C2) chronic pain, disability, fatigue, C3) high cost/dz activity, less pain, C4)comorbidities w/ $$$ https://t.co/Azc35zyA9J
Dr. John Cush RheumNow
5 years ago
RA DMARD use gleened from 86 rheumatologists recording Rx choices/reasons on next 12 pts. Total: 1027 RA pts, 621 already on b/ or tsDMARD (68% TNFi, 21% JAKi). ~Half who switched given another TNFi . Reasons: LOE, dz worsening https://t.co/zpjSO25wsh
Dr. John Cush RheumNow
5 years ago
EULAR has received reports of tocilizumab shortage in several countries, including Germany, Portugal, Belgium, and Scandinavia. The UK and France are aware tocilizumab concerns, but have not yet reported actual shortages https://t.co/7QpjZTXXAK
Gout is a common comorbidity amongst those with chronic kidney disease (CKD), with the added challenge of choosing best therapies in the setting of declining renal function. A systematic literature review notes significant deficiencies regarding the efficacy and safety outcomes of gout flare prophylaxis and therapy stratified by different levels of renal dysfunction.
Dr. John Cush RheumNow
5 years ago
A longitudinal study from Iceland shows an increasing number of native joint infections (NJI), with iatrogenic, postarthroscopic infections being of particular concern.
Read more…
https://t.co/n82PpZ7a96 https://t.co/j3gzZ9g0QV
Dr. John Cush RheumNow
5 years ago
DEA has warned of an increase in illegal counterfeit pills containing fentanyl & methamphetamine. These often look Rx opioids (Oxycontin, Percocet, Vicodin), Xanax or Adderall. DEA seized >9.5 million fake pills (more than last 2 yrs) https://t.co/Y0gJ4XrV1a

