Dr. John Cush RheumNow
5 years ago
Prospective study of 77 RA patients in remission --> vax w/ BNT162b2 (BioNTech-Pfizer) (w/ temp D/C of DMARDs per ACR) found a vaccine-related flare rate of 7/8% (6 pts) w/ 5/6 flares after 2nd dose (2.6 days), resolved w/in 2 wks https://t.co/YOL3YVArvG #RheumNow https://t.co/dxRWhu8CJX
A consensus report from a multinational group of 91 scientists, clinicians and public health professionals alarmed the medical world last week as they suggest the use of acetaminophen (paracetamol) during pregnancy may have hazardous developmental effects on the fetus.
Dr. John Cush RheumNow
5 years ago
Can I get the INFLUENZA and COVID Vaccines together? The CDC says: "YES...both vaccines can be given at the same visit, people should follow the recommended schedule for either vaccine.... ideally get a flu vaccine by the end of October." https://t.co/T49zm6Cxyc
Dr. John Cush RheumNow
5 years ago
Patients with rheumatoid arthritis (RA) who had a history of cancer did NOT have an increased risk of new or recurrent cancers if treated with biologic therapies, a meta-analysis found. #RheumNow
https://t.co/jM9oiRzXUk https://t.co/XYnaalEfe2
NEJM NEJM
5 years ago
NEJM Image Challenge: A patient presented with painful and erythematous plaques on his hands and elbows. Lab examinations showed leukocytosis and thrombocytopenia. What is the diagnosis? https://t.co/kQrNuVmVXg https://t.co/4JGeExCcP7
Rheum OnePagers RheumOnePagers
5 years ago
Aortitis: Let’s review the differential for #aortitis including Non-Infectious and Infectious Causes!
@febrilepodcast x @RheumOnePagers | created by @MithuRheum @swinndong
#IDTwitter #RheumTwitter #FOAMed https://t.co/pR0iTls4PK
AmericanJournalofHematology AjHematology
5 years ago
New study on #COVID19Vaccine in autoimmune cytopenias
🩸7.4% had clinically significant ⬇️ in counts
🩸 All successfully managed w/steroids & transfusion
🩸 Mild ⬇️ in 10% AIHA and 20% ITP
⭐️Vaccination safe with close monitoring⭐️
https://t.co/qGZe6LiPKz
Dr. John Cush RheumNow
5 years ago
Pooled analysis of the DISCOVER-1 and DISCOVER-2 trials have shown that guselkumab, an IL-23 inhibitor, was effective and safe in psoriatic arthritis (PsA) patients with axial involvement and imaging-confirmed sacroiliitis. #RheumNow
https://t.co/yLCxyC1oLr https://t.co/Uloqx2phlh
Dr. John Cush RheumNow
5 years ago
The #1 question I get from new consults: “How did I get arthritis?” Here is my list of 11 drugs (or drug classes) known to cause arthritis or rheumatic disorders (as an unintended consequence). #RheumNow https://t.co/GsV0Qj9ENr https://t.co/IrTkY5yFdY
Dr. John Cush RheumNow
5 years ago
Study of 435 #SLE pts seen during the pandemic. Comparing those seen F2F vs telemedicine, there was no significant difference in SLE disease activity (by SLEDAI-2K) or SLE flare rates or steroid prescribing between visit types https://t.co/kscU9CbqVM
Dr. John Cush RheumNow
5 years ago
Prescribe antimalarial dosages at 5 mg/kg/d or less.... A baseline retinal exam w/ optical coherence tomography should be performed w/in 6 mos...to rule out confounding Dz. Pts at low risk for retinopathy do not require annual screening until 5 years.. https://t.co/l3sCxOJLNJ
Dr. John Cush RheumNow
5 years ago
Encouraging DBRPCT of Rituximab in #PMR: 116 screened, 49 enrolled, 47 completed: 23 on RTX vs 24 on PBO. Steroid-free remission at 21 wks seen with 11/23 (48%) RTX pts vs 5/24 (21%) on PBO (p=0·049). Infusion Rxns: 10 RTX vs 3 PBO); 1 SAE (PE) on RTX https://t.co/U2ZGNrpi0i
Patients with rheumatoid arthritis (RA) who had a history of cancer did not have an increased risk of new or recurrent cancers if treated with biologic therapies, a meta-analysis found.
Almost three years ago to the day, I did a podcast entitled, "I wanna new drug." As I go over this week's podcast, I want to say it again. I want a new drug safe enough to use during pregnancy, for PMR, for GVHD, and more. I'm going to cover these, and other topics including lupus, COVID breakthrough infections, and statin use and the risk of RA, as I review the news and journal articles from the past week on RheumNow.
