Dr. John Cush RheumNow
5 years 1 month ago
Rheumatic Flares Uncommon After COVID Vax
https://t.co/fuyC50K5UF
Post-vaccination disease flares were uncommon among patients with rheumatic and musculoskeletal diseases who were inoculated against COVID-19, researchers found. https://t.co/jp0ZoRqnla
Dr. John Cush RheumNow
5 years 1 month ago
Study of 708 newly Dx rotator cuff disorder shows that 6 sessions of Progressive exercise was not superior to a 1 physiotherapist session in improving shoulder pain and function. Subacromial corticosteroid injection provided no long-term benefits https://t.co/Flqv286MVV
Dr. John Cush RheumNow
5 years 1 month ago
Study of 1821 pregnant women with autoimmune disorder. 74% used acetaminophen during pregnancy (HA, pain, injury). The highest (5th quintile use thru wk 20) acetaminophen had a modest risk (HR 1.62) of preeclampsia vs none https://t.co/DXxaSkTZs7
medRxiv medrxivpreprint
5 years 1 month ago
Clinical characteristics and outcomes of COVID-19 breakthrough infections among vaccinated patients with systemic autoimmune rheumatic diseases https://t.co/xftj12BgzX #medRxiv
Eric Topol EricTopol
5 years 1 month ago
The Israeli data for increased mRNA-vaccination breakthrough infections and "waning immunity" is finally available
https://t.co/9j73Q7L7Nn h/t @Aiims1742
Overall 2X risk, no statistical significant difference between age groups, but trend of increase w/ age https://t.co/D4IpFm6Ydl
A large, single-rheumatology center analysis of oral and subcutaneous (SC) methotrexate (MTX) use in daily clinical practice suggests that SC MTX has fewer drug discontinuations and is better tolerated compared to other DMARD therapies.
It was a banner week at the FDA; a new drug approval you should know about; a lot of information about pregnancy and safety; and an interesting case plus a question from one of our readers submitted via Back Talk. This and more in this week's podcast. Let's dive in.
Dr. John Cush RheumNow
5 years 1 month ago
D-penicillamine Adverse events reported to FDA (1970-2020): dystonia (OR 20.52), drug hypersensitivity (OR 5.42), pancytopenia (OR 10.2), joint swelling (OR 9.07), Renal (OR 6.68), dysphagia (OR 5.05), CHF (OR 4.04), edema (OR: 3.77) https://t.co/8lmYiJo2Tz
The NEJM has published a multicenter study wherein patients with surgical lumbar spinal stenosis and degenerative spondylolisthesis were found to fair equally well (noninferior if treated with decompression surgery alone compared to decompression with instrumented fusion.
A retrospective cohort study examined the need for joint replacement surgery in juvenile idiopathic arthritis (JIA) and showed there has been a trend to delay arthroplasty over time. The JIA category, year of implant, and presence of complications significantly affected implant survivorship.
Dr. John Cush RheumNow
5 years 1 month ago
Serum adipokine CTRP9 levels may predict severe lung dz in Systemic Sclerosis (SSc-ILD): Retrospective longitudinal Registry/Biorepository study; 110 SSc pts - 31% had elevated CTRP9 assoc w/ lower FVC. Low CTRP9 assoc w/ FVC Stability. https://t.co/AY4U12kwPr
Dr. John Cush RheumNow
5 years 1 month ago
54-year-old man with several weeks of diffuse abdominal pain/tenderness. Feet and hands showed diffuse petechia. CT scan - occult ileocecal perforation and segmented small bowel wall thickening in Intestinal skip lesions. Most likely diagnosis?https://t.co/DaeiC1gqln
Dr. John Cush RheumNow
5 years 1 month ago
A retrospective analysis of the ACR RISE registry shows that multimorbidity is not only common in patients with active rheumatoid arthritis (RA), but also impacts treatment choices and outcomes.
https://t.co/72Lcqxjoly
Dr. John Cush RheumNow
5 years 1 month ago
Retrospective study of 80 kids w/ systemic JIA - 12 pts changed anakinra to cananinumab & continued w/ clinical inactive Dz (CID). 68 active sJIA Rx w/ CAN: 57% CID off GCs at 6 mos & 64% at 12 mos. NonResponse predicted by #active jts ≥5, hx of MAS https://t.co/QkmqzRrjp6
