Dr. John Cush RheumNow
5 years 5 months ago
55 pts w/ Multi-joint osteonecrosis (>2 jts).( SLE 29%, ALL 11%, HIV 9%, EtOH 4%). Mean cumulative steroid dose >30 g over 5 yrs. Predictors of MJON was cumulative oral steroid dose (3.2% incr per 1000 mg. MJON risk incr 12 X w/ 2nd risk factor https://t.co/dqTPh2PV8V https://t.co/HTrSnZSefK
Dr. John Cush RheumNow
5 years 5 months ago
Study of 207 Pediatric pts treated w/ Rituxan (for Rheum, Cancer, CNS, Renal dz) and 40% developed hypogammaglobulinemia post-RTX; hypo-IgG Pre-RTX 28.7% to Post RTX 42.6%, p=0.009; low IgG levels had higher risk of serious infx (OR 2.3) https://t.co/b91rPYgVV2
Dr. John Cush RheumNow
5 years 5 months ago
A Patient-Centered Exploration of Axial Involvement in SpA
Sponsored by Novartis Medical Affairs
Listen to a medical expert differentiate axial involvement within the spectrum of spondyloarthritis.
https://t.co/o2q5pTP3WD https://t.co/GiqdIqitMB
Dr. John Cush RheumNow
5 years 5 months ago
Great reminder of from Dr. Kathryn Dao, @KDAO2011 from #RNL2021
Caution! Verrucous LE can simulate skin cancer! Both can be found in photosensitivity areas!
#RheumNow
Herpes zoster reactivation -- a.k.a. shingles -- following COVID-19 vaccination in six patients with comorbid autoimmune/inflammatory diseases may be a new adverse event associated with the Pfizer/BioNTech mRNA vaccine, suggested a new report.
Dr. John Cush RheumNow
5 years 5 months ago
Shared from #RNL2021 from @uptoTate
"Absence of proof of an effect is not proof of absence of an effect!" Dr. Kavanaugh's sage reminder for the day"
A new study of calcitonin gene-related peptide (CGRP) antagonists for migraine headaches found that a small subset manifested Raynaud phenomenon and other had microvascular complications, suggesting that CGRP antagonists should be used in caution in patients with Raynauds.
Dr. John Cush RheumNow
5 years 5 months ago
Tonight! Join us for Tuesday Night Rheumatology with Dr. Philip Robinson and Dr. Iain McInness. We'll discuss highlight sessions for RheumNow Live 2021 #RNL2021
https://t.co/oJ4xYKLrj4 https://t.co/K1OQz40aZ1
Dr. John Cush RheumNow
5 years 5 months ago
News Feature: Planes, Trains and COVID Distancing
MMWR reports the risk of acquiring an infection with SARS-CoV-2 is reduced 23% to 57% when the middle seat was vacant (compared with full aircraft occupancy).
https://t.co/tGs9GopeGu https://t.co/ZRMltTpYgW
Dr. John Cush RheumNow
5 years 5 months ago
News Feature: Broadalumab Efficacy in Axial Spondyloarthritis
Broadalumab, an anti-interleukin-17 receptor A monoclonal antibody, is FDA- approved for use in adults with plaque psoriasis; but a recent trial shows it to be effective in patients with axSpA.
https://t.co/V0zKbFMgy7 https://t.co/U5CGXUF7Sw
Dr. John Cush RheumNow
5 years 5 months ago
Dual seropositivity with RF/ACPA autoantibody higher titers were strongly associated with prevalent RA-ILD (OR 2.90; developed in 3.7%). ILD more likely with high titer RF (HR 3.4) than high titer CCP (HR 1.9). https://t.co/ebvJjatQSw
Dr. John Cush RheumNow
5 years 5 months ago
304 pts w/ Knee OA studied by MRI and atorvastatin 40 mg qd was no better than placebo in reducing cartilage volume loss, BM lesions, pain, or function over 2 years https://t.co/MIdIFQ9qzs
Dr. John Cush RheumNow
5 years 5 months ago
Serious problem! Pulmonologists uniformly believe that MTX causes and/or worsens ILD. MTX causes hypersensitivity pneumonitis, not ILD. RA, lupus DM, PSS cause ILD and they may need MTX to manage their disease. Do your own research, look at this paper to start. https://t.co/DHC5ikhCf6
Ethan Craig rheumecraig
5 years 5 months ago
There's a special, deep hell for insurers/PBM's that give patients a hassle over paying for a cheap drug like methotrexate.
And these days it's looking like it's going to be very, very crowded.
Ruth Dobson drruthdobson
5 years 5 months ago
Another @preventiveneur1 paper just published. @tomrptaylor looked at demyelinating events reported in people taking anti-TNF in the BSRBR. We found that these events are uncommon in people with underlying rheumatological disease https://t.co/qCaF6YMLAh
