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Low Persistence of Biologics in Psoriatic Arthritis

A longitudinal observational cohort study of psoriatic arthritis (P

Dr. John Cush RheumNow

5 years 8 months ago
Low Persistence of Biologics in Psoriatic Arthritis A longitudinal observational cohort study of psoriatic arthritis (PsA) patients treated with biologic therapy finds relatively low persistence of selected biologic therapy in PsA patients. https://t.co/CzQnpAnttW https://t.co/uYU778rwod
QD Clinic - "I Don't Know"--What to Say When you Don't Have a Diagnosis to Deliver

https://t.co/HcJAXRYTyc

Dr. John Cush RheumNow

5 years 8 months ago
QD Clinic - "I Don't Know"--What to Say When you Don't Have a Diagnosis to Deliver https://t.co/HcJAXRYTyc
QD Clinic - No Win Consults
Lancet Rheumatology has reported the results of a proof of concept trial, wherein vagal nerve stimulation was shown to ameliorate RA disease activity. The intervention involved non-invasive stimulation of the auricular branch of the vagus nerve using a wearable vagus nerve stimulation device for up to 30 min per day, delivering pulses of 20 kHz.
One-Third Rheumatoid Risk from Lifestyle

Analysis of the NHANES data suggests that 1/3 of the risk of developing RA in

Dr. John Cush RheumNow

5 years 8 months ago
One-Third Rheumatoid Risk from Lifestyle Analysis of the NHANES data suggests that 1/3 of the risk of developing RA in the USA is attributable smoking, obesity and alcohol intake. https://t.co/jLLmEvXg2O https://t.co/ZG1hcJ7QVJ
Abbvie has released data from KEEPsAKE-1 and KEEPsAKE-2 studies (1407 pts) showing Risankizumab (IL--23 inhibitor) is ef

Dr. John Cush RheumNow

5 years 8 months ago
Abbvie has released data from KEEPsAKE-1 and KEEPsAKE-2 studies (1407 pts) showing Risankizumab (IL--23 inhibitor) is effective in Psoriatic arthritis; RIS Rx pts achieved ACR20 of 57% and 51% at week 24 (vs PBO 34% and 27%; p<0.001) https://t.co/wPQMqLnhOO
Metanalysis of 24 studies finds pregnant women, w/ inflammatory disease, exposed to biologics had NO increased risk of c

Dr. John Cush RheumNow

5 years 8 months ago
Metanalysis of 24 studies finds pregnant women, w/ inflammatory disease, exposed to biologics had NO increased risk of congenital anomalies (adj OR 1.18; 0.88, 1.57), but had increased preterm births (OR 1.61; 1.37, 1.89) & low birth weight (OR 1.68) https://t.co/KqTDmfFf9H
French study of 782 men (50-85 years) with DISH found DISH was associated with increased vertebral fractures (OR 2.89; 9

Dr. John Cush RheumNow

5 years 8 months ago
French study of 782 men (50-85 years) with DISH found DISH was associated with increased vertebral fractures (OR 2.89; 95% CI, 1.15-7.28; P <.05), but Nonvertebral fractures were not associated with DISH (HR 0.72; 0.33-1.56). https://t.co/YoQ8r62pns
QD Clinic - When RA Meets UC
British registry 801 axial SpA pts; 646 did not hve fibromyalgia at baseline &amp; 46 (7%) developed FM over time. Of 11

Dr. John Cush RheumNow

5 years 8 months ago
British registry 801 axial SpA pts; 646 did not hve fibromyalgia at baseline & 46 (7%) developed FM over time. Of 115 axSpa w/ baseline FM, 77 (2/3) recovered. FM more likely with high Dz activity ((OR 1.27) & widespread pain (OR 1.14) https://t.co/4jOdaXIJuB https://t.co/ruOYj5HmMX
Our Top January Tweet:

Urate Lowering Therapy During Acute Gout

Acute gout has its well-defined protocols, and most st

Dr. John Cush RheumNow

5 years 8 months ago
Our Top January Tweet: Urate Lowering Therapy During Acute Gout Acute gout has its well-defined protocols, and most state that urate lowering therapy should be continued; but does ULT affect outcomes in an acute gout attack? https://t.co/aDHpU1qrlu https://t.co/6xDwyVjuyC
Multiple intraarticular steroid injxs NO better than placebo. Analysis of 6 RCTs show no diff in pain than PBO (−0.47

Dr. John Cush RheumNow

5 years 8 months ago
Multiple intraarticular steroid injxs NO better than placebo. Analysis of 6 RCTs show no diff in pain than PBO (−0.47, 95% CI −0.62, 0.31). 14 RCTs + 2 Observ. studies show IA steroids may cause mor cartilage loss or risk of joint replacement (HR 2.54) https://t.co/jCLq4jWn4Y
Analysis of the NHANES (National Health and Nutrition Examination Survey) data suggests that one-third of the risk of developing rheumatoid arthritis (RA) in the USA is attributable smoking, obesity and alcohol intake.
Consults in Cars
In this episode of Dialing for Doctors (aka, Tales of Telehell), we consider a growing subset of telehealth seekers connecting from their cars. This has happened several times and it always catches me surprise. While I've had "live" televideo visits with patients walking the dog, waking up in bed, and from the waiting room of another doctor's office, consults in cars is about the nuttiest. What is the patient's role in telehealth?
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