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Does Allopurinol lower mortality in gout? Metanalysis of 4 studies were split 2 yes, 2 no and overall all-cause mortality just missed significance wit

Dr. John Cush RheumNow

6 years 6 months ago
Does Allopurinol lower mortality in gout? Metanalysis of 4 studies were split 2 yes, 2 no and overall all-cause mortality just missed significance with and adjusted HR 0.80 (95%CI (0.60, 1.05). https://t.co/sTB0Aq1lPd
RT @NYTHealth: Wearing a face mask takes some getting used to. To get the most benefit, you need to avoid these common mistakes. https://t.…

NYT Health NYTHealth

6 years 6 months ago
Wearing a face mask takes some getting used to. To get the most benefit, you need to avoid these common mistakes. https://t.co/MwLirqZdyN
Chikungunya infection acutely shows fever, polyarthralgia, polyarthritis, HA, rash & GI Sxs; up to 60% develop chronic polyarthritis that mimics #

Dr. John Cush RheumNow

6 years 6 months ago
Chikungunya infection acutely shows fever, polyarthralgia, polyarthritis, HA, rash & GI Sxs; up to 60% develop chronic polyarthritis that mimics #RA. A retrospective report of 48 pts Rx w/ MTX (mean 9.2/wk) shows signif better pain and swollen joints. https://t.co/XEbvjSQOlx
Sweets syndrome in NEJM: 54 yoM with UC has 3d of fever and abdominal pain after surgery, developed painful pustules and vessicles on neck and trunk

Dr. John Cush RheumNow

6 years 6 months ago
Sweets syndrome in NEJM: 54 yoM with UC has 3d of fever and abdominal pain after surgery, developed painful pustules and vessicles on neck and trunk w/ WBC 18k, ESR 40 and Bx w/ neutrophils and edema in the upper dermis. https://t.co/g1SDNS0CMS
Henderson et al article in A&R details the Immunopathology, inflammatory mediators operative in cytokine storm syndrom of COVID-19 (and MAS/HLH),

Dr. John Cush RheumNow

6 years 6 months ago
Henderson et al article in A&R details the Immunopathology, inflammatory mediators operative in cytokine storm syndrom of COVID-19 (and MAS/HLH), how to assess them and treatment options. Smart and timely article. (free read) https://t.co/3tsEVYMVRM
Treatment options for painful knee osteoarthritis (OA) are numerous, but comparative outcomes are seldom available. A NEJM report shows that physical therapy is superior to intraarticular glucocorticoids injections assessing the outcomes 12 months after the intervention. 
The presentations of the COVID-19 infection have been clearly chronicled with the worrisome onset of sore throat, dry cough, loss of smell and taste with fevers, myalgias, fatigue and the worrisome progression of pulmonary involvement in a minority.  Lab findings may include a leukocytosis, lymphopenia, and elevated LDH and hepatic enzymes. Nevertheless there are several other organ systems that can be involved.
Xray Chondrocalcinosis does not predict the need for future TKR. Study of 656 knee OA patients found 93 (14.2%) with knee Chondrocalcinosis, and 91 (

Dr. John Cush RheumNow

6 years 6 months ago
Xray Chondrocalcinosis does not predict the need for future TKR. Study of 656 knee OA patients found 93 (14.2%) with knee Chondrocalcinosis, and 91 (13.9%) who went onto TKR. TKR odds - not affected by the presence of knee CC (HR 1.26; 0.74–2.17) https://t.co/3JKzFjSvK1
FDA Grants Fast Track Designation to Telitacicept as a Treatment for #SLE. Telitacicept is a recombinant fusion protein of TACI receptor & the Fc

Dr. John Cush RheumNow

6 years 6 months ago
FDA Grants Fast Track Designation to Telitacicept as a Treatment for #SLE. Telitacicept is a recombinant fusion protein of TACI receptor & the Fc domain of IgG1, inhibiting B cell activity by neutralizing BLyS and APRIL. + results at #ACR2019 https://t.co/7ndMWb2Rjf
The Journal of Rheumatology reports a retrospective, single center, analysis of 17 rheumatoid vasculitis patients who responded well to intravenous rituximab (RTX) therapy.They identified 17 patients treated with RTX for systemic rheumatoid vasculitis from 2000 to 2017. At RV diagnosis, mean age was 59 years, 59% were female, 94% were white, and 82% had positive rheumatoid factor.
Check out my take on the new ACR COVID-19 Guidance for Rheumatic Disease Patients - great suggestions; but I do have a few thoughts that differ....wha

Dr. John Cush RheumNow

6 years 6 months ago
Check out my take on the new ACR COVID-19 Guidance for Rheumatic Disease Patients - great suggestions; but I do have a few thoughts that differ....what do you think? https://t.co/8srDPYRo0b
"Real strength has to do with helping others." - Mr Rogers

Dr. John Cush RheumNow

6 years 6 months ago
"Real strength has to do with helping others." - Mr Rogers
Congratulations to the ACR's North American Task Force in rising to the occasion so quickly to put forth the ACR COVID-19 Clinical Guidance for Patien

Dr. John Cush RheumNow

6 years 6 months ago
Congratulations to the ACR's North American Task Force in rising to the occasion so quickly to put forth the ACR COVID-19 Clinical Guidance for Patients with Rheumatic Diseases https://t.co/IFu8tvMpCh
On April 11th, the ACR Board of Directors approved a COVID-19 guidance document written by an ACR task force charged with updating and clarifying recommendations for rheumatologists and rheumatic disease patient management during the current COVID-19 crisis.
The 9/11/01 terrorist attach on the World Trade Center (WTC)  resulted in at least 2,977 fatalities, over 25,000 injuries, and caused at least $10 billion in infrastructure and property damage.  Arthritis & Rheumatology reports that dust cloud exposure among responders and PTSD among community members was associated with a significant increased risk of new‐onset systemic autoimmune disease. 
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