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QD Clinic - Managing Comorbidities in Psoriatic Patients
The Rheumatologists Role in Comorbidity Management
QD Clinic - Managing Comorbidities in Psoriatic Patients
The Rheumatologists Role in Comorbidity Management
QD Clinic - Managing Comorbidities in Psoriatic Patients
The Rheumatologists Role in Comorbidity Management
QD Clinic - Managing Comorbidities in Psoriatic Patients
The Rheumatologists Role in Comorbidity Management
An Italian study examined the outcomes in adult onset Still's disease (AOSD) based on whether they received early or delayed treatment with anakinra (ANK).  A total of 141 AOSD patients were retrospectively studied. Overall, they found no differences in efficacy if ANK was started within 6 (or 12 mos) vs. thereafter.  
While there are numerous agents approved for use in juvenile idiopathic arthritis, little is know about actual use biological disease-modifying antirheumatic drug (DMARD) use or switching in the biologic era. A cohort comparison study has shown that after an unsuccessful trial of a first biologic, changing to a second TNFi is as effective as switching to a non-TNFi biologic.
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TNF inhibitors may slow, but do not stop, Xray progression in AS, Anti–IL-17A agents may maybe the same. Study by Inman et al shows that Tyk2 inhibi

Dr. John Cush RheumNow

6 years 7 months ago
TNF inhibitors may slow, but do not stop, Xray progression in AS, Anti–IL-17A agents may maybe the same. Study by Inman et al shows that Tyk2 inhibition may prevent xray damage (animal model) by blocking IL-23 signaling and IL-22 production. https://t.co/OyyKoqdCl9
Dr Alan Menter #UTSW Rheum Grand Rounds the cause of death in psoriasis is mostly cardiovascular https://t.co/PPQqO4rS5h

Dr. John Cush RheumNow

6 years 7 months ago
Dr Alan Menter #UTSW Rheum Grand Rounds the cause of death in psoriasis is mostly cardiovascular https://t.co/PPQqO4rS5h
CORRONA study of 24,528 #RA pts; 32% also has Sjogrens syndrome (overall SS prevalence in RA = 0.30 ). SS more likely with increasing RA duration, old

Dr. John Cush RheumNow

6 years 7 months ago
CORRONA study of 24,528 #RA pts; 32% also has Sjogrens syndrome (overall SS prevalence in RA = 0.30 ). SS more likely with increasing RA duration, older, female, seropositive; higher DZ activity; more comorbidities and extra-articular manifestations https://t.co/EgTSzKHmtL
193 #RA pts starting a TNFi followed for 12ms; 21.7% were non‐adherent to TNFi - No difference between different TNFi's. Predictors of nonadherence

Dr. John Cush RheumNow

6 years 7 months ago
193 #RA pts starting a TNFi followed for 12ms; 21.7% were non‐adherent to TNFi - No difference between different TNFi's. Predictors of nonadherence included High age, low DZ activity, ^^comorbidities, more injection site pain & Rxns https://t.co/qclzJiglMj
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