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Earlier Anakinra Initiation Warranted in Still's Disease

Mar 12, 2020 2:38 pm

An Italian study examined the outcomes in adult onset Still's disease (AOSD) based on whether they received early or delayed treatment with anakinra (ANK). 

A total of 141 AOSD patients were retrospectively studied.

Overall, they found no differences in efficacy if ANK was started within 6 (or 12 mos) vs. thereafter.  

However, starting ANK earlier (

ANK effectiveness in controlling systemic inflammation and resolving articular manifestations is more obvious when IL-1 inhibition is initiated soon after disease onset.

The author has no conflicts of interest to disclose related to this subject

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