JAMA Dermatology reports that after the onset and diagnosis of hidradenitis suppurativa (HS), such patients have a higher risk of certain forms inflammatory arthritis.
Dr. John Cush RheumNow
6 years 8 months ago
#MLK - “We will remember not the words of our enemies, but the silence of our friends.” Martin Luther King, Jr.
Dr. John Cush RheumNow
6 years 8 months ago
IL-37 may be a target for psoriasis. IL-37 is downregulated in lesional skin & IL-37 serum levels correlate with psoriasis severity. IL-37 is an anti-inflammatory & immunosuppressive cytokine from IL-1 family. Tofacitinib may increase IL-37 in psoriasis https://t.co/jPaGlcDFV2
Dr. John Cush RheumNow
6 years 8 months ago
Population based study of ~72K chinese people shows that the DASH diet was assoc with significantly (30%) lower risk of hyperuricemia - more pronounced among older people (≥50 y), women and physically inactive (<0.01 for all). #Gout https://t.co/Ns1KzD5PfM
Dr. John Cush RheumNow
6 years 8 months ago
Plasmapheresis Indications : TTP, HUS, Cryoglobulinemia, Hyperviscosity, Myasthenia gravis, Goodpastures, Catastrophic APL Syn, Chr inflamm demyelinating polyneuropathy, Removal of drugs/toxins, Alveolar hemorrhage, ANCA vasculitis (questionable) https://t.co/Prw62LB6WH
Dr. John Cush RheumNow
6 years 8 months ago
#MLK - “If I cannot do great things, I can do small things in a great way.” Martin Luther King Jr.
QD Clinic - Lessons from the clinic
Active HBV infection (HGsAg+) on anti-viral therapy but needs a biologic - what should you use?
QD Clinic - Lessons from the clinic
The Consult that shows up without a cause - and what to do?
Dr. John Cush RheumNow
6 years 8 months ago
Hydroxychloroquine in RA metanalysis shows clinical efficacy of HCQ was similar to or lower than MTX or SSZ monotherapy. When HCQ combined with other DMARDs it increased the clinical efficacy. There is a paucity of data on HCQ structural (Xray) benefits https://t.co/Q5ukHrjybJ
The availability of biologic biosimilars has thus far had negligible impact on prescribing practices in the United States, in stark contrast to what has been observed in some European countries, researchers reported.
Dr. John Cush RheumNow
6 years 8 months ago
A of TB risk with TNF inhib - Risks by country:
- Worldwide - 9.62 cases/1000 pts exposed
- Asia, 13.47 /1000
- S America 11.75 /1000
- Europe, 6.28 /1000 patients
- North America 4.34 /1000
(low risk (USA, EU) and high risk countries (Asia, S.Amer).
https://t.co/MNtnjbEuMS
Dr. John Cush RheumNow
6 years 8 months ago
Anti-transcription intermediary factor 1 (TIF1)-γ autoantibodies are linked with cancer-associated Dermatomyositis in adults https://t.co/DeBoDdEbV1
